B-15A collides with Antarctic ice tongue
...updated. In that sense, release of these sequences makes the results of experiments using Agilent arrays far more valuable." This announcement is being made in conjunction with the extensive release of microarray experimental data into the public domain by the National Toxicology Program. Icoria Inc., und...Plant Sacrifices Cells to Fight Invaders
...death throughout the plant. When a plant pathogen makes contact with its intended target, the plant cells immediately launch a set of sophisticated molecular responses. Such defense mechanisms, including PCD, are similar to immune responses exhibited by animal cells when they are fighting a disease-causin...Study reveals candidate targets for anti-retroviral therapeutics
...rug resistance in isolates of the AIDS virus, HIV, makes identification of new antiviral targets an urgent necessity. Host genes required to support the replication of HIV are a potential source of such novel targets, but relatively few appropriate target genes have been identified in animal cells thus far...Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells
... Kurtzberg. The ease of obtaining cord blood also makes it an excellent source of stem cells, she said. Cord blood is readily available because it is extracted from discarded placentas (afterbirth) following child birth. Adult bone marrow must be harvested from living donors through an invasive surgical p...Discovery clarifies role of peptide in biological clock
..., Sara Aton, found that mice lacking the gene that makes VIP or lacking the receptor molecule for VIP suffer from internal de-synchrony. When they recorded the electrical activity of SCN neurons from these mice, they found that many had lost their beat while others were cycling but unable to synch to each ...Breakthrough isolating embryo-quality stem cells from blood
... rigid "cytoskeleton" to hold them in shape, which makes them stretchier than normal cells. Käs and Guck's machine uses a powerful beam of infrared laser light to stretch and measure cells one by one. His optical stretcher differs from an existing tool known as optical tweezers in which the light is focus...Molecular thermometers on skin cells detect heat and camphor
... molecular thermometer--perhaps the first one that makes skin cells able to sense warm temperatures. Now they have demonstrated that the receptor does indeed detect heat by examining the physiological and behavioral characteristics of a knockout mouse with no TRPV3 proteins. The mice appear completely nor...Sugar beet virus mutation requires Texas touch
...eld to the molecular aspects of the pathogen. That makes our program totally unique." Outside research dollars began pouring in and Rush's program was reinvigorated in 2002 when a new strain of beet necrotic yellow vein virus emerged. The new strain threatened sugar beet production in California and Minn...Research into how prions act in the brain could hold the key to defeating diseases
... of Biological Sciences are examining exactly what makes particular nerve cells in the brain more susceptible to attack by prions. 'We are looking ultimately at ways of early detection and diagnosis so effective treatment can begin as soon as possible,' said Professor Perry. 'There is much we do not know ...Bee mites suppress bee immunity, open door for viruses and bacteria
...den hive collapse. Something else is involved that makes bee mites so harmful to bee colonies. The Penn State researchers report their findings in today's (May 17) online version of the Proceedings of the National Academy of Science. Yang and Cox-Foster looked at how bee mites affect the bee immune syste...Research shows smoking adds a decade to reproductive age of IVF patients
...e reproductive age of a 20-year-old. This means it makes her the equivalent of a 30-year-old non-smoker in reproductive terms. "However, it also indicates that subfertile couples may help their chances of successful treatment by life-style changes. As the effects of smoking and overweight were greatest am...Nanobacteria in clouds could spread disease, scientists claim
...s of a sticky protein (slime) coating nanobacteria makes them act as extremely efficient cloud condensation nuclei, with a tendency to aggregate to clusters upon contact." Their work corroborates the findings of Ruprecht Jaenicke, of the Institute for Atmospheric Physics at Mainz University, Germany, on b...Mutation in clams protects against paralytic shellfish poisoning but raises human health risk
...h changes a single amino acid in a sodium channel, makes nerves less sensitive to those toxins. The discovery is reported in the April 7 issue of the journal Nature. The authors suggest that it has wide ranging implications for the evolution of shellfish in the presence of toxic algae and increases the ri...DOE JGI launches IMG public online microbial genome data clearinghouse
...Computational biologists have led the way, but IMG makes it possible for evolutionary biologists without first-rate computer skills to compare fungal and bacterial genomes and scrutinize fundamental processes like speciation and adaptation." In addition to curating the IMG system, DOE JGI will continue to...Pair of cancer genes found to drive both cell migration and division
...helps the cell decide where to push outward - PI3K makes PIP3 on the membrane on one side of a cell while PTEN breaks it down on the other side. But when both enzymes are missing, levels of PIP3 remain constant throughout the membrane, and the cell can't migrate properly. In experiments with single-celled...Newly discovered protein an important tool for sleeping sickness research
...variant surface glycoprotein (VSG). The human body makes antibodies for VSG, but trypanosomes randomly swit...have been trying to understand how the trypanosome makes base J. The discovery of JBP2, a member of a protein family that helps control DNA-related function...Breakthrough System for Understanding Ocean Plant Life Announced
...variant surface glycoprotein (VSG). The human body makes antibodies for VSG, but trypanosomes randomly swit...have been trying to understand how the trypanosome makes base J. The discovery of JBP2, a member of a protein family that helps control DNA-related function...Active Vaccine Prevents Mice From Developing Prion Disease
...ts of other animals contaminated with prions. What makes these infectious particles unusual is that they are proteins that have the same amino acid composition as equivalent proteins occurring naturally in the body. But the prions turn deadly by changing shape. These "misfolded" proteins tend to aggregate ...Researchers pioneer new gene therapy technique using natural repair process
.... "That we can fix mutations in human immune cells makes us very optimistic that this therapy will work in several other diseases, such as sickle cell disease." Sickle cell disease is a disorder in which blood cells carry a mutation in hemoglobin. The mutation causes the blood cells to change shape, preve...Searching the depths of the straits of Florida for disease cures
...s such as Bimini before heading for the bank. This makes for a long trip that deters most. Divers who do make the journey are fond of Cay Sal because of its spectacular reefs, extensive cave systems, and abundant sea life, including the elusive whale shark. Harbor Branch scientists are attracted most to i...