Purdue proves concept of using nano-materials for drug discovery
...ontains numerous pores. This "nanoporous" material makes it possible to carry out reactions inside the vessels. The goal is to produce "laboratories-on-a-chip" less than a half-inch square that might contain up to a million test chambers, or "reactors," each capable of screening an individual drug, said G...Researchers identify target for cancer drugs
...utated and unable to function, Akt breaks free. It makes its way to the cell membrane where other proteins activate it, thereby enabling Akt to contribute to tumor growth. "When a cell loses PTEN through, say, a mutation, Akt goes gangbusters," says Sabatini. The exact means by which Akt switches on when ...Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
...f cell in our bodies contains the same genes. What makes them do different things involves which genes are ...d Schreiber enlisted the help of Affymetrix, which makes so-called "gene chips" that rapidly scan millions of small sections of chromosomes to detect gene ac...Critical role in programmed cell death identified
...art of it. It unifies two different hypothesis and makes worms a great model to analyze how cell death is i... the same time and at the same place. This feature makes it possible to identify mutant worms, in which cells that should have died instead live. Worms whose...ASU researchers finds novel chemistry at work to provide parrot's vibrant red colors
...e aspects, he wanted to understand more about what makes the colors of the birds possible, and then focused on "deconstructing the color into its component parts." McGraw said an interesting aspect of the five polyenal lipochromes that provide the red in parrots, is that the pigment is found only in the b...Transport System Smuggles Medicines Into Brain
...e aspects, he wanted to understand more about what makes the colors of the birds possible, and then focused on "deconstructing the color into its component parts." McGraw said an interesting aspect of the five polyenal lipochromes that provide the red in parrots, is that the pigment is found only in the b...Probing The Promise And Perils Of Nanoparticles
...es engineering make them less harmful, but it also makes them better at what we want them to do. You don't lose anything; it's all a gain." More recently, Leroueil studied other types of charged nanoparticles called polycationic polymers—already being used to deliver drugs and genes—to see if they behaved...Researchers trace evolution to relatively simple genetic changes
...ons, the research team found that one gene is what makes the difference. "Now, for the first time, we've b...es." Research had already shown that the Eda gene makes a protein, a signaling molecule called ectodermal dysplasin. This molecule is expressed in ectoderma...Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
...ons, the research team found that one gene is what makes the difference. "Now, for the first time, we've b...es." Research had already shown that the Eda gene makes a protein, a signaling molecule called ectodermal dysplasin. This molecule is expressed in ectoderma...Development of portable infectious disease detector
...itor the health of small groups of cells, however, makes it possibleto detect the presence of unknown poisons as long as they affect cellmetabolism. Furthermore, by examining the impact that an unknown agenthas on different cell types--such as heart, lung, nerve, skin,etc.--this approach also can rapidly p...New SARS Protein Linked To Important Cell Doorway
... their efforts revealed orf7a, a SARS protein that makes its home in a structure cells use to modify proteins destined for transport to the cell surface. Researchers don't have any hard evidence of orf7a's function, but they speculate that the protein's positioning could enable it to block proteins that he...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
... numbers of potential species andreaction channels makes things very difficult."Computer simulations can be powerful tools in contemporary molecularbiology research, aiding scientists in analyzing data and in testinghypotheses with simulated outcomes before testing them experimentally.The predictive capabi...UCLA scientists transform HIV into cancer-seeking missile
...re Medicine. The scientists added the protein that makes fireflies glow to the virus in order to track its ... the scientists added luciferase ?the protein that makes fireflies glow ?to the AIDS virus. They injected the camouflaged HIV into a vein in the mouse's tail...The BIOS Initiative - open source biotechnology is born
...In the tradition of open source software, BioForge makes it possible for scientists to work together to craft new, deliverable technologies within a "protected commons". "BioForge is a hands-on, evolving tool kit to make things happen. BioForge is about sharing capabilities and building communities of inn...Antibodies from plants protect against anthrax
...ransfers the gene into the plant cells. "The plant makes the antibody for you in a few days," says Baillie. The antibodies were then purified from leaves harvested from the infected plants and tested for their ability to protect mice against anthrax infection. The plant-produced antibodies were just as ef...UCSD discovery may help extend life of natural pesticide
...Diego has discovered a molecule in roundworms that makes them susceptible to Bacillus thuringiensis toxin, or Bt toxin--a pesticide produced by bacteria and widely used by organic farmers and in genetically engineered crops to ward off insect pests. Their findings should facilitate the design and use of B...Scientists identify new model Of NK cell development
...happen to reside in lymph nodes, too." Freud also makes the provocative observation that lymph nodes, while full of CD56 bright cells, are significantly lacking in their counterparts, the CD56 dim cells. "Our next goal is to determine if there is some developmental continuum at work here, supporting the ...The very unexpected life and death of a leukemic cell
...tes into glucose and the tagged glucose eventually makes its way into the cell's DNA. Researchers gave 19 individuals with CLL a small dose of heavy water every day for 84 days, and the tagged water was incorporated into the DNA of the leukemia cells. This provided the researchers a way to track the cell ...New RNA polymerase discovered in plants
...rnative form of either Polymerase I (Pol I), which makes the largest of the ribosomal RNAs, Pol II which makes RNAs for protein-coding genes, or Pol III, a specialist in making the shortest of the ribosomal RNAs...Bird Brains Show How Trial and Error May Contribute to Learning
...se lab is funded in part by a grant from HHMI. "It makes sense that one part of the brain has as part of its job introducing that kind of variability." Kao began with an experiment to stimulate the region of the forebrain called LMAN (lateral magnocellular nucleus of the anterior nidopallium). In the avia...