Wisconsin scientists discover a master key to microbes' pathogenic lifestyles
...study. "These microbes have to undergo an extreme makeover to survive in a host," says Klein, an authority on fungal diseases. "The million dollar question is was what controls this change? " Klein and colleagues Julie C. Nemecek and Marcel Wuthrich identified a molecular sensor that is conserved in these s...In a technical tour de force, Salk scientists take a global view of the epigenome
...m that in a mature skin or nerve cell. Part of the makeover mature cells must undergo for therapeutic cloning purposes will likely involve remodeling methylation patterns to resemble those of stem cells. And disease states, ranging from retardation to cancer, are marked by aberrant methylation: some carcinoge...