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Tag: "make" at biology news

Stem cells from brain transformed to produce insulin at Stanford

...ormally made by islet cells, and they continued to make some proteins found in neurons. Nonetheless, the fact that they could respond to sugar by producing insulin was exciting. Kim's next step was to find out if the cells could perform the same feat in a mouse. The group transplanted the cells into a ca...

New component of the 'brakes' on nerve regeneration found

...ion as a component of the complex of proteins that make up this receptor. The puzzle, however, was that p75 is not widely made in the adult neurons in which this inhibitory receptor complex is known to function. The two research groups turned their attention to TAJ/TROY because it is a member of the same...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...cal product development process, urging changes to make the process “more predictable and less costly.?The... the drug was measured and that number was used to make dosing decisions,?said Derendorf, whose work is primarily funded by the pharmaceutical companies Pfi...

Scientists discover how plants disarm the toxic effects of excessive sunlight

...ead researcher on the paper. "This finding should make it possible to modify plants and other photosynthetic cells to avoid the toxic effects of singlet oxygen, which could impact agriculture and the treatment of human and plant disease, and aid the effort to create alternative bioenergy sources," Donohu...

Researchers identify protein crucial for survival of Lyme-disease bacterium

...esearchers genetically altered the Bb bacterium to make a "knockout" form that lacked a gene that codes for the protein BptA. Without the protein, bacteria were unable to utilize the blood on which the tick feeds when it bites a victim. "As far as we can tell, Bb bacteria normally utilize blood as their ...

Multi-purpose protein regulates new protein synthesis and immune cell development

...rotein called IRE1, which helps stressed-out cells make new proteins, may be more versatile and important than scientists believed. A new study by researchers from the University of Michigan Medical School and the Howard Hughes Medical Institute reveals the surprising finding that this same signaling prot...

Gene therapy promising for growing tooth-supporting bone

...id that was ideal because the team did not want to make any permanent genetic changes. The gene acted quickly to get bone growth started, then disappeared within about 28 days. Giannobile said a next step in this process could include looking for non-viral approaches to delivering gene therapy to the def...

Computational Method Speeds Mapping of Cell Signaling Networks

...ry research teams are working on new approaches to make the process faster and easier. One such group, le...s going on inside the cell. But the molecules that make up individual pathways in signaling networks rarely operate in isolation--they "talk" to each other ...

GeneNotes - A novel information management software for biologists

...ase with tons of information... and your job is to make sense of this puzzle in a biologically meaningfull way. Applications are being developped to make it all easier, leaving the fun part : biology! GeneNotes is one of them; I didn't have time to try i...

Researchers find new genes necessary to make embryo

...evious estimates of how many genes are required to make an embryo. Their study focused on the genes expres...y discovered over 150 additional genes required to make an embryo beyond what was previously known, leading them to conclude that many more genes will be fo...

Marburg haemorrhagic fever in Angola update

...ugh 2000, had a case fatality of 83%. Two factors make the rapid detection of outbreaks of Marburg haemorrhagic fever difficult: the extreme rarity of this disease and its similarity to other diseases seen in countries where deaths from infectious diseases are common. Neither the source nor the date of t...

New insight into regulation of blood stem cells

...stem cell (HSC), which can either "self-renew" and make more copies of itself or differentiate into either red blood cells, various types of white blood cells, or platelets. The genes that control proliferation and differentiation have been difficult to study using traditional gene disruption methods beca...

Nanoparticles offer new hope for detection and treatment

...s patients at Barnes Jewish Hospital. "We can also make these particles so that they can be seen with nucl...ow. Nevertheless, melanoma has unique traits that make it especially interesting as a target for nanoparticle therapy. Melanoma has a horizontal phase, whe...

Buying Time Through Hibernation on Demand

...iminating oxygen dependence in healthy cells could make them a less-vulnerable target for radiation and ch...gh chemistry' ?it's simply an agent that all of us make in our bodies all the time to buffer our metabolic flexibility. It's what allows our core temperatur...

U-M team recovers ancient whale in Egyptian desert

...iminating oxygen dependence in healthy cells could make them a less-vulnerable target for radiation and ch...gh chemistry' ?it's simply an agent that all of us make in our bodies all the time to buffer our metabolic flexibility. It's what allows our core temperatur...

Chemicals in tattoo inks need closer scrutiny

...ain better understanding is to know what chemicals make up the inks, the researchers say. Finley-Jones and Wagner expect that the variation found in their testing and the potential presence of toxic metals will encourage regulators to begin monitoring the tattoo ink industry more closely. There are other...

Strongest proof yet found for prion hypothesis

...noculation. "For many years, people have tried to make these infectious prions in test tubes, because what is needed to prove the prion hypothesis completely is to be able to produce this process in vitro in the absence of living cells and thus rule out the presence of a virus," said Claudio Soto, profes...

Reservoirs may accelerate the spread of invasive aquatic species, researchers say

...e physical and biological properties of reservoirs make them more likely to be invaded by exotic species than natural lakes. The researchers point to cases in which reservoirs are believed to have facilitated the rapid spread of invasive species. The authors note that reservoir construction often leads t...

FDA Announces Series of Changes to the Class of Marketed Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

...to include a Medication Guide for patients to help make them aware of the potential for CV and GI adverse events associated with the use of this class of drugs. In addition, FDA is asking the manufacturers of all OTC NSAIDs to revise their labels to include more specific information about the potential C...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

...m. "Delaying the transplant even a week or two can make a noticeable difference in a child's motor skills, so timely diagnosis and treatment is essential to preserving brain and motor function." Children transplanted after onset of symptoms do stabilize but exhibit minimal neurologic improvement, said Ma...

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