Scientists identify new model Of NK cell development
...they learn their role. In contrast, B cells, which make antibodies, remain and mature in the bone marrow. ...ytometry, they discovered that while NK precursors make up about 1 percent of bone marrow progenitor cells and 6 percent of circulating blood progenitor cel...New RNA polymerase discovered in plants
... a template of DNA genetic information in order to make RNAs that encode proteins or that function directl...n death in mice. Pikaard thinks that Pol IV helps make siRNAs that then direct DNA methylation to sequences matching the siRNAs. The results were publishe......lies in the production of pure chiral drugs, which make up over one-third of all pharmaceutical drugs currently sold worldwide. Chiral drugs are comprised of “left-handed?and “right-handed?molecules, both of which are mirror images of each other. Only one of these molecules provides the therapeutic effect...RNA project to create language for scientists worldwide
...y to head the consortium. "This," he added, "will make it easier to turn molecular information into usefu...oftware controlling how the genes are expressed to make proteins." They are unique in being able to store and transmit information as well as process that i...Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits
...cription of all protein-interaction circuits would make such a model possible. "We'd like to simulate diseased cell types, such as cancer cells, and then simulate the effects of drugs on those diseased cells," said Ideker. "Ultimately, we think this kind of a systems biology approach will have a very bene...South America's vast pantanal wetland may become next everglades, UNU experts warn
...ered by drainage projects starting in the 1940s to make way for development and agriculture. In a message to mark World Water Day, March 22, UNU says the Pantanal provides enormous environmental services by storing and purifying water, providing storm protection and flood mitigation, and stabilizing the ...Falling ants glide back to trunk to avoid dangers of forest floor
...eet and occasionally bounce off. They can actually make 180 degree turns in midair, however, so even when ...nk, though, as Yanoviak initially noted, they just make a 180 degree turn and try again ?usually with success. What allows the ants to change direction so ...World's largest rainforest drying experiment completes first phase
...ess of the sugar and other carbohydrates that they make to wood production. This finding has important implications for climate change since the amount of carbon removed from the atmosphere during tropical droughts will decrease significantly. In addition, there are implications for sustainable forest man...Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
...n University scientists have "programmed" cells to make their own contrast agents, enabling unprecedented high-resolution, deep-tissue imaging of gene expression. The results, appearing in the April issue of Nature Medicine, hold considerable promise for conducting preclinical studies in the emerging fiel...In the migratory marathon, parasitized monarchs drop out early
...is so. Explanation : infected monarchs quite don't make it while migrating long distances, so they can't propagate the infection once arrived at destination. A little-studied outcome of animal migration is whether these long journeys can limit the spread of parasites by weeding out diseased animals. Mon...Scientists find fossil proof of Egypt's ancient climate
...s much as 600 millimeters per year, "not enough to make it a paradise," Smith said, "but enough to turn a ...e, enough to shrink it substantially in volume and make it more saline would have been expected to result in large excursions in d18O and minor element conc...Implanted Devices Detect High-Risk Heart Failure Patients
...match with their actual clinical status, which can make it difficult for cardiologists to get a true idea ...role in the treatment of heart failure, and how to make best use of the new data which they can provide. Additional trials will be needed to tease out the r...Affymetrix and Stratagene Announce Strategic Software Alliance
...ssion microarrays. In April 2005, Affymetrix will make ArrayAssist Lite available to its existing GeneChip customers via the Internet and will also begin pre-installing the software on new GeneChip workstation desktops. Through an easy-to-use interface and tightly integrated workflow, ArrayAssist Lite wi...PCRM develops world's first cruelty-free insulin assay
..."We have proven that if researchers are willing to make the effort, there are effective, humane alternatives to animal-based assays and other testing procedures--alternatives that could help save the lives of millions of people and animals." There are an estimated 194 million people worldwide with diabet...Sequencing of marine bacterium will help study of cell communication
... other organisms. (Among the four nucleotides that make up DNA ?adenine, guanine, thymine, and cytosine (ATGC) ?'A' pairs with 'T' and 'G' pairs with 'C'. The more GC content, the more tightly DNA strands bind.) Despite the fact that it is a symbiont, V. fischer's genome contains genes that may have toxi...Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss
... of the eye and replaces it with saline. They then make a pinpoint opening in the retina through which they inject fluid to lift up a portion of the retina from the back of the eye, creating a small pocket in the "subretinal space" just wide enough to accommodate the ASR. The surgeons then enlarge the po......cost. In this way we see considerable potential to make it possible for players of all scales in this industry to meet both long and short term objectives of cost savings, and the eventual development of oligonucleotide drugs that are affordable to patients,?stated Dr. Kenji Matsumoto, President of Kinova...International HapMap consortium expands mapping effort
...se of the HapMap Project has allowed scientists to make important analyses of the human genome that were n...willing to contribute some of its own resources to make this possible," said Kelly A. Frazer, Ph.D., vice president of genomics at Perlegen. "We are confide...Ophthalmologists implant five patients with artificial silicon retina microchip
... of the eye and replaces it with saline. They then make a pinpoint opening in the retina through which they inject fluid to lift up a portion of the retina from the back of the eye, creating a small pocket in the "subretinal space" just wide enough to accommodate the ASR. The surgeons then enlarge the po...Protein offers way to stop microscopic parasites in their tracks
... the parasite used at least four of those genes to make active proteases. When they looked at where and wh...ed that only TgROM5 could cleave the proteins that make up the adhesive spots. "There's a great deal of interest in this because TgROM5 might someday be ta...