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Tag: "make" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

... addition of four bromine atoms. The bromine atoms make the hole at the top of the molecule smaller, which makes it more difficult for things to pass in and out. This is ideal if you're trying to capture certain molecules and hold them until they're ready for release, the researcher says. Superbowl molec...

DNA Molecules Used To Assemble Nanoparticles

...imer clusters are in the works. "If you wanted to make a therapeutic that targeted five drugs to five different cells, it would be 25 synthesis steps the traditional way," Baker said. At two to three months per synthesis, and a significant loss of yield for each step, that approach just wouldn't be pract...

Man and mouse share genome structures

... is vital to learn how the genome is translated to make living cells and organisms, and how we can use that information to improve human health," said Bernstein, who is an instructor of pathology at Brigham & Women's Hospital and Harvard Medical School. "Every one of our cells has the same genome, yet...

Researchers discover way to make cells in the eye sensitive to light

...an important proof of principle that melanopsincan make non-light sensitive cells receptive to light, and although nota cure, could have applications in treating some forms of blindness."Dr Rob Lucas, from the University of Manchester, and one of the paper'sauthors, adds: "The discovery that melanopsin is...

Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants

...ventional fluorescent markers and their small size make them idealfor biological imaging. The researchers then added the molecules togerminated lily pollen grains and examined them under a confocalmicroscope.This is the very first time that Quantum Dots have been utilized forlive imaging in plant systems....

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...ally inherited copy turned off. As a result, cells make a double dose of the IGF2 protein and are said to have "loss of imprinting" of IGF2. Although Feinberg and others have already noted an association between loss of imprinting of IGF2 and colon cancer in people, the current experiments were designed ...

Columbia research lifts major hurdle to gene therapy for cancer

...erapy, especially forcancer, is really starting to make a comeback."The virus's selectivity for cancer cells is based on two moleculescalled PEA-3 and AP-1 that, the researchers found, are usually abundantinside cancer cells. Both of the molecules flip a switch (called PEG)that turns on the production of ...

Priming embryonic stem cells to fulfill their promise

...generating liver cells fromembryonic stem cells to make an artificial liver. She plans to seekfunding to further her artificial liver research from the newCalifornia Institute for Regenerative Medicine. The institute wascreated after California voters in November approved Proposition 71, ameasure that aut...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...tti said. In type 1 diabetes, the pancreas cannot make the hormone insulin at all; about 1 million Americ...mated 18 million Americans -- the pancreas doesn't make enough insulin or the body's cells develop a resistance to its effect. Without insulin, glucose cann...

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

...r cells (EPCs), which isthe type of cell needed to make new blood vessels and to repair damagedones.Patients in the clinical trial will be given an injection of either agrowth factor called GM-CSF (granulocyte-macrophage colony stimulatingfactor) or placebo (sterile salt water) three times a week for twow...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

..., even though human cells aregenetically unable to make it. In a related paper published November29, 2004 by the Journal of Biological Chemistry (JBC), the Varki grouphas also discovered the exact cellular mechanism by which this occurs. Instudies with one of the federally approved human embryonic stem c...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...s also will help us understand why it's so hard to make an HIV vaccine, and will help us start strategizing about new approaches to vaccine development." The studies, performed in the Children's Hospital Boston Laboratory of Molecular Medicine, used the closely related simian immunodeficiency virus (SIV)...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...ts havepreviously demonstrated that such swellings make it difficult orimpossible for nerve-cell branches to send signals.After showing that the swellings were mostly stable in number and sizeover the course of three to seven days, Brendza injected Abetaantibodies directly onto the surface of the mouse br...

Key molecule in plant photo-protection identified

...ts havepreviously demonstrated that such swellings make it difficult orimpossible for nerve-cell branches to send signals.After showing that the swellings were mostly stable in number and sizeover the course of three to seven days, Brendza injected Abetaantibodies directly onto the surface of the mouse br...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...n embryonic development of melanocytes ?cells that make and store the pigments in the skin and hair ?is al...rom the vast majority of differentiated cells that make up organs where cancers are found. If this theory is correct, resident stem cells in the skin could ...

Timing is everything: First step in protein building revealed

...he right place along a gene's instructions,it will make the wrong protein, which can kill the cell or lead todisease."The ribosome is the end stage of gene expression, and gene expressionkeeps us alive and causes disease," says Lorsch. "If we can betterunderstand how the ribosome works, perhaps we can har...

Tiny particles could solve billion-dollar problem

...ficient enough to provide the throughput needed to make the whole approach effective. Tests in Wong's lab have found that the gold-palladium nano-catalysts break TCE down about 100 times faster than bulk palladium catalysts. ...

Researchers Uncover Key Step In Manufacture of Memory Protein

...een converted to active mBDNF. Because they cannot make mBDNF, CPE-deficient mice have poor long-term memory. Dr. Loh added that, in the near future, an understanding of the chemical mechanism she and her colleagues deciphered in the current study may provide insight into long-term memory deficits. She e...

Research advances quest for HIV-1 vaccine

...y reveal some special characteristics of 4E10 that make it unusually effective at targeting this region. Drs. Burton and Wilson are members of a scientific consortium of laboratories, the International AIDS Vaccine Initiative's Neutralizing Antibody Consortium (IAVI), which is focused on understanding br...

Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering

...amento - Today, Affymetrix, Inc.announced plans to make eight new GeneChip(R) plant and animal genomearrays available in 2005 as part of its Consortia Program, includingcanine, Rhesus macaque, Medicago trancatula (legume), Brassica, tomato,citrus, poplar and sugar cane. More than 20 research presentations...

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