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St. Jude study solves mystery of mammalian ears

...ar the question has been whether the cilia are the main engine of sound amplification in both mammals and non-mammals. One group of scientists believes that somatic motility in mammalian outer hair cells is simply a way to change the height of the cilia in the fluid to maximize the force with which the ...

One species, many genomes

...f local adaptation, and this was indeed one of the main reasons for conduction the study. "By extending these types of studies to other species we hope to help breeders to produce varieties that are optimally adapted to rapidly changing environmental conditions," explains Weigel. He is already collaborati...

Identified main genetic variants involved in response to HIV

...n, known as association study, permitted to deduct main genetic variations playing a central role in the control of viral infection. Results point to two gene variants related to the immune system. More precisely, these variations are in a genetic region responsible for the determination of immune respo...

Cells re-energize to come back from the brink of death

...ells that have cheated death once by disabling the main suicide pathway called apoptosis can also foil a backup self-destruct program, which allows them to survive and become cancerous. The St. Jude study also suggests that a drug that disrupts a cancer cell’s ability to block this backup program woul...

Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes

...e cancer is inoperable, chemotherapy is one of the main treatment options, and still the prognosis is dismal. Survival is often measured in months. Researchers, led by Winnie Yeo of the Chinese University of Hong Kong, examined the significance of pre-chemotherapy HBV DNA levels in the blood on the sur...

Hormone helps mice 'hibernate,' survive starvation

...ls on the brink of starvation normally shift their main fuel source from carbohydrates to stored fats, promoting survival during foodless periods. Some mammals also enter a hibernation-like state of regulated hypothermia, known as torpor, which conserves energy. The molecular driver behind this reactio...

Research shows cord blood comparable to matched bone marrow

...arly all cord blood donors were mismatched. The main objective of the research was to compare the results after cord blood and marrow transplantation and provide guidelines to transplant physicians on the selection of the best donor for children with leukemia. Remarkably, mismatched cord blood perform...

Newly discovered antibody may be body's natural defense against Alzheimer's

... scientists to speculate that oligomers may be the main culprit in Alzheimer's and therefore a prime target for a new generation of disease-modifying treatments. To further confirm that these natural antibodies bind with oligomers, Dr. Relkin and his colleagues collaborated with Drs. Charles Glabe and...

Study shows lizard moms dress their children for success

... lizards for nearly 20 years. He said the lizards' main predator, the coachwhip snake, is a highly efficient hunter, and the lizards need just the right combination of traits to avoid being eaten. "The females are dressing their progeny for success, because they need a different back pattern in differe...

Surprising origin of cell's internal highways

...ion. Microtubules are the largest of the three main types of filaments that make up the cytoskeleton -...structures, the centrosome has been considered the main origination point for microtubule "nucleation" in most cells. Until now. "I've seen that there a...

'Virtual autopsy' helps identify drowning as cause of death

...the subglottic (below the vocal cords) trachea and main bronchi. Fourteen (50 percent) had sediment in the subglottic airways. Six (21 percent) had frothy fluid in the airways, and 25 (89 percent) had ground-glass opacity and thickening in the lungs. Twenty-five (89 percent) exhibited swelling of the sto...

Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism

...enesis of atherosclerosis. Atherosclerosis is the main cause of morbidity and mortality worldwide. Classic risk factors including smoking, diabetes, hypertension and high cholesterol levels are known to play a pivotal role in the pathogenesis of the disease that also recognises a genetic influence. Howev...

Want to save polar bears? Follow the ice

...ice becomes more distant and inaccessible. The main question for conservationists is which of the existing 18 populations of polar bears occurring on two continents and one sub-continent stand the best chance of surviving as the polar cap shrinks in size. To that end, the project will utilize remote s...

Detecting cold, feeling pain: Study reveals why menthol feels fresh

...ab cloned the gene for the capsaicin receptor, the main pungent ingredient in some chili peppers (Nature, Oct. 23, 1997), and in 2000 reported that, in mice, the receptor triggers the nerves to fire pain signals when they are exposed to high ambient heat or the fiery properties of peppery food. (Science, ...

'Virtual Patient' to simulate real-time organ motions for radiation therapy

... and a moving organ such as the lung or heart is a main concern in radiation treatment or imaging of tumors that are affected by such organ movement," Xu said. "In order to determine accurate and effective radiation dosages, doctors must consider such issues as the breathing function and air volume change...

Simple home spit test to spot deadly pre-eclampsia

... relating to the implantation of the placenta. The main diagnostic symptoms are raised blood pressure and the excretion of protein in the urine. While there is no cure, other than the delivery of the baby and removal of the faulty placenta, early detection and management of the problem can have a big impa...

Brain's white matter -- More 'talkative' than once thought

...s on oligodendrocyte precursor cells (OPCs), whose main role when they mature into oligodendrocytes is to wrap themselves around and insulate nerves with a whitish coat of protective myelin. The immature cells simply hang around and divide very slowly, waiting to be spurred into action. To learn more ...

New knowledge improves rice quality

...reasingly affluent rice consumers in Asia. The main aim of the new International Network for Quality Rice is to help rice breeders around the world develop varieties with improved quality traits such as better taste, aroma, and cooking characteristics as well as higher levels of nutrition. Once provid...

Double the death rate from cirrhosis for 'blue collar' men

...s (SES). Heavy or binge drinking is one of the main contributors to the development of liver cirrhosis. Professor Najman said the study results suggested that men from lower socio-economic backgrounds were in greater danger of liver cirrhoses because of their heavy and binge drinking. Liver ci...

LIAI scientists make important finding on cytomegalovirus transmission

...nt recipients or AIDS patients. Ware said, "The main importance of these experiments is identifying the critical molecular targets controlling virus persistence, and two ways in which we can modulate immunity in vivo with the desired result of blocking virus spread to uninfected individuals. "The po...

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