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Tag: "lymphoma" at biology news

Source of molecular triggers in cutaneous T cell lymphoma identified

...te first identified CTCL as a separate category of lymphoma thirty years ago. The Yale research group reported that, like all T cells, the cancerous CTCL cells require antigenic stimuli delivered by specialized dendritic cells of the epidermis, referred to as Langerhans cells (LC), in order to replicate. To...

Potential Cure for Lymphoma in HIV patients

...able option for select patients withHIV-associated lymphoma will be published in the January 15, 2005,issue of...V, HIV-positivepatients are more likely to develop lymphoma than HIV-negativeindividuals, and the treatment for their cancer is far less likely tobe successful....

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

...ent issue of Molecular Cell Biology (MCB). B-cell lymphoma is a cancer in which the antibody-producing cells ...d. "Instead, this gene promotes the development of lymphoma by enlarging the B lymphocyte population. This increases the likelihood that at least a few of the c...

New Treatment Rivals Chemotherapy For Lymphoma, Study Finds

...s easy as it sounds. A new form of treatment for lymphoma that takes a fraction of the time of traditional c...er found. Patients with advanced-stage follicular lymphoma ?a cancer generally considered incurable ?who had not been previously treated with any other form of...

Mayo Clinic Researchers Create 'Obedient Virus'; First Step To Use Measles Virus Against Cancer

... kinds of human cancer cells -- ovarian cancer and lymphoma -- and is probably still years away from use as a human therapy. But the concept has at last been proved in mice with human cancer tumors -- and that's an essential step toward using this approach to expand and improve human treatments for a variety ...

Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

... had lower risks of Kaposi sarcoma and non-Hodgkin lymphoma compared with those who did not use HAART, althoug...use was not associated with lower risks of Hodgkin lymphoma or other cancers. Although people infected with HIV had increased risks of cancers of the lung, lip,...

Viral protein influences key cell-signaling pathway

...he infection will lead to adult T cell leukemia or lymphoma (ATLL). ATLL is an aggressive disease characterized by a long latent period and the proliferation of T lymphocytes. The virus is spread by sexual activity, by contact with infected blood and by infected women to children through breast milk. HTLV-1,...

Emergence of cancer as major cause of childhood death in developing countries is not being adequately addressed

... to successfully treat children who have Burkitt’s lymphoma using a single drug, cyclophosphamide. Such twinning projects can be supported initially by the partner in the more affluent country, the authors say. Local charitable groups can raise funds to support an oncology program. Another benefit of twinnin...

U of T researchers map role of Epstein-Barr virus in cancer

...ly linked to certain b-cell cancers like Burkitt's lymphoma as well as the epithelial cell cancer, nasopharyngeal carcinoma. EBNA1 is a protein coded in the Epstein-Barr virus and suspected to play a role in the development of cancer," says Lori Frappier, professor in medical genetics and microbiology at U of...

USC researchers determine mechanism of action of chemotherapy drug

... properties of cells from human lung, prostate and lymphoma cancer cell cultures that had been treated with motexafin gadolinium, or MGd. What they found was that the drug created oxidative stress in the tumor cells, increasing the levels of expression of the genes that produce metallothioneins. The research...

Sleeping beauty plays a significant role in identifying cancer genes

...hich was mutated in 50 percent of mice with T cell lymphoma induced by Sleeping Beauty. The same gene is mutated in about 50 percent of people with a similar type of cancer. We believe the Sleeping Beauty method will allow us to identify many other such genes for other cancers." *Collier L., Carlson C., Ravi...

Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue

...cancer of the lymphatic system. Like many cancers, lymphoma cells have well-defined surface receptors that rec...he role of a Trojan horse. Dai and Dean Felsher, a lymphoma researcher in the Stanford School of Medicine, have begun a collaboration using laboratory mice with...

MicroRNA may have fail-safe role in limb development

...as been linked to diabetes, hepatitis C, leukemia, lymphoma and breast cancer. But only now have microRNAs been connected to actual growth processes. "We found miR 196 expressed only in the hindlimbs of mice, not the forelimbs - in other words, the feet but not the hands," said Brian Harfe, Ph.D., an assist...

Combination therapy improves AIDS-related lymphoma outcome

...sponded as well to therapy and survived as long as lymphoma patients without HIV. Lymphomas are cancers of t...rates comparable to those in non-HIV patients with lymphoma treated with CHOP and superior to previously published rates achieved by CHOP alone. For standard-ri...

Mouse study reveals human X-SCID gene therapy poses substantial cancer risk

... and found that one-third of the animals developed lymphoma later in their life. This is the same gene being g...is about one-and-a-half years. Mice that developed lymphoma did so at an average of 10 months of age. In the human gene therapy trials, leukemia did not appe...

BiovaxID?yields 89 percent survival in patients with aggressive non-Hodgkins

...ovaxID yielded an 89% survival rate in mantle cell lymphoma patients. The median follow-up was 3.8 years. Historically, patients with this type of lymphoma only have had a 50% chance of surviving 3 years and 20% chance of surviving 5 years. BiovaxID, an in...

Viral protein helps infected T cells stick to uninfected cells

...of those infected develop adult T cell leukemia or lymphoma (ATLL), an aggressive disease characterized by a long latent period and the proliferation of T cells. The infected cells are spread from person to person during sexual activity and by blood and breast milk. In the body, the HTLV-1 mainly targets im...

Spousal illness can trigger partner death

...e 4 percent increase no effect Leukemia or lymphoma no effect no effect Pancreatic Cancer no effect no effect Colon Cancer no effect no effect Lung Cancer no effect no effect All other forms of cancer no effect no effect All other diagnoses 2 percent increase ...

Single microRNA causes cancer in transgenic mouse

...into the development of some forms of leukemia and lymphoma and at the same time underscores the powerful role that these tiny snippets of non-coding RNA play in cell signaling pathways active in carcinogenesis. "To the best of our knowledge, this is the first direct evidence that overexpression of a microR...

Cancer virus protein needed for successful infection

...of those infected develop adult T cell leukemia or lymphoma (ATLL), an aggressive disease characterized by a long latent period and the proliferation of T lymphocytes. The virus is spread by sexual activity, infected blood and breast milk. For this study, Lairmore and a group of collaborators developed a mu...

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