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Tag: "lymphatic" at biology news

Imaging Lymph Nodes with Nanoparticles

... workup is assessing whether or not there has been lymphatic spread. Currentmethods include surgical removal of nodes for examination and varioustypes of imaging, ranging from ultrasound to newer technologies such asmagnetic resonance imaging (MRI). All these methods have problems; someare very invasive, other...

Enzyme allows B cells to resist death, leading to leukemia

...mature B lymphocytes in the blood, bonemarrow, and lymphatic tissues. It is believed that in the early stagesof disease, B-CLL is the result of an undefined defect in theprogrammed signals that trigger normal B cell death (apoptosis). LivioTrentin and colleagues from Padua University School of Medicine nowdemo...

A bacterial genome reveals new targets to combat infectious disease

...rugia malayi, a parasitic nematode responsible for lymphatic filariasis. This Wolbachia genome is small, only about a million base pairs, and many metabolically critical genes have degraded through mutation to the point of uselessness. This phenomenon, called reductive evolution, is typical of long-term symbi...

Tadpole soon to help in the fight against cancer and lymphedema

...culates in our bodies through a complex network of lymphatic vessels, of which little is known. This network is...help of tadpoles. This accelerates research of the lymphatic vessel network. With tadpoles one can now very quickly identify new genes that play a part in the de...

Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue

... cell." One example is lymphoma, or cancer of the lymphatic system. Like many cancers, lymphoma cells have wel...r-infrared light on the animal's skin will destroy lymphatic tumors, while leaving normal cells intact. "It's a really interesting idea," says Felsher, an assis...

Researchers discover why melanoma is so malignant

...arby tissue, then make their way into the blood or lymphatic vessels. Next they must migrate through the bloodstream to a distant site, exit the bloodstream, and establish new colonies. Researchers have wondered why melanoma in particular is able to do this not only more efficiently than other cancers, but at ...

A New Era of Hope for the World's Most Neglected Diseases

...livery mechanism in order to simultaneously target lymphatic filariasis, onchocerciasis, soil-transmitted helminthiases, schistosomiasis, and trachoma (Lancet 365: 1029?030). Thirdly, and perhaps most importantly, the neglected diseases have at long last caught the attention of the international development c...

Malaria parasites develop in lymph nodes

...iver. However, many of the parasites also invaded lymphatic vessels. About 25 percent of the parasites injected by the mosquito bites were drained by lymphatic vessels and ended up in lymph nodes close to the site of the bite. Their journey seemed to stop ther...

APS lecturer shows rare video of 'teacher-student' immune cell interactions in live animal

...them apart and bring the pieces (antigens) via the lymphatic system to the nearest lymph node. When the dendrit...that deposits a few bacteria, which travel via the lymphatic system to the lymph node and proliferate to huge numbers. One of the puzzles von Andrian has been wo...

Speeding discovery of the 'human cancer genome'

...ormal microenvironment, traversing into and out of lymphatic or blood vessels, and proliferating in new "soil," the researchers said. Metastasis is particularly important in skin cancer, Chin added, as the primary tumor is almost always curable. Once the cancer spreads from the skin to other parts of the bo...

Scientists discover why cornea is transparent and free of blood vessels, allowing vision

...th VEGFR-3, which is usually found on cells lining lymphatic vessels, to stimulate the growth of lymphatic vessels. Dana's team began to suspect the involvement of VEGFR-3 in stopping blood growth in corne...

Scientists find a key to immune system's ability to remember

...r. Unlike naïve T cells, which are confined to the lymphatic system, memory T cells are found everywhere in the body, enabling them to sense and react more quickly when an infectious agent is reencountered. "Now we know one of the reasons we get such a quick response and clearance (of the pathogen) with rei...

Development of gene therapy

...o the efficacy of gene therapy in treating chronic lymphatic leukaemia and haemophilia B. But successes in clinical testing come with their share of setbacks, such as the currently slight margin of therapeutic effectiveness over unwanted side effects. This underscores the necessity to carefully assess risks an...

Cancer-killing invention also harvests stem cells

...am can capture significant amounts of cells of the lymphatic and circulatory systems, and potentially mesenchymal stem cells, which are unspecialized cells that form tissue, bone, and cartilage. Current procedures enable the specific capture of hematopoietic stem cells, which grow (or differentiate) over time...

The quest for an effective HIV vaccine presents new possibilities, challenges

...oughout the body and establishes HIV reservoirs in lymphatic tissues. Within weeks of exposure, virus levels peak and then decline to levels that may remain low for months or years. It is believed that CD8+ T cells--so-called killer T-cells--are responsible for this reduction in HIV levels; however, their abil...

Risk of lymphoma increases with hepatitis C virus infection

...sk of developing certain lymphomas (cancers of the lymphatic system), according to a study published in the May...een hepatitis C virus infection and cancers of the lymphatic system," said NCI Director John E. Niederhuber, M.D. "Since so much is still unknown about the caus...

Migration alert -- How tumor cells home in on the lymphatic system

...stic description of how tumor cells migrate to the lymphatic system in the early stages of tumor metastasis. Th... Scientists know that tumor cells spread via the lymphatic system, but they don’t understand the details of how this deadly migration takes place. In the June ...

Enzyme delivered in smaller package protects cells from radiation damage

...adiation often is given to patients with blood and lymphatic cancers to wipe out their bone marrow cells prior to subsequent transplantation of hematopoietic stem cells, bone marrow stem cells or peripheral blood progenitor stem cells. However, there is increasing concern that such high doses of radiation may ...

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