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Tag: "lymph" at biology news

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

...f locoregional radiation therapy (radiation to the lymph nodes and chest wall) to a course of chemotherapy ...ter radical mastectomy in premenopausal women with lymph node–positive breast cancer. Between 1979 and 1986, 318 patients were randomly assigned to receive n...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

...f locoregional radiation therapy (radiation to the lymph nodes and chest wall) to a course of chemotherapy ...ter radical mastectomy in premenopausal women with lymph node–positive breast cancer. Between 1979 and 1986, 318 patients were randomly assigned to receive n...

Imaging Lymph Nodes with Nanoparticles

... to reconstruct a virtual picture of the patient's lymph nodes,thus potentially allowing accurate surgical removal of the nodes....

Potential Cure for Lymphoma in HIV patients

...cfactors: either the cancer had spread to multiple lymph nodes or thepatient had bulky disease (indicated by a cancerous mass greater than 5?10 cm).Reversible abnormalities in liver function, a side effect of theintensive treatment, were experienced in a majority of the patients.One patient, the oldest in ...

Scientists identify new model Of NK cell development

...found in cellular nurseries deep inside the body's lymph nodes. The findings, appearing in the Mar. 22 iss...ry, had noted other work showing that mice lacking lymph nodes also lacked NK cells. In addition, in earlier research in Caligiuri's laboratory, scientists h...

New Treatment Rivals Chemotherapy For Lymphoma, Study Finds

... leading cause of cancer death, is a cancer of the lymph system, which is part of the immune system. Lymphoma spreads easily through the lymph system and the bloodstream and consequently tends to be widespread when it is diagnosed. Traditional...

A little stress gives beneficial oomph! to immune system

...battle stations ?primarily the skin along with the lymph nodes that drain the skin. "Most immune challenges or wounds involve on the skin or other epithelial linings of the body," Dhabhar said. "If nothing happens immunologically following stress ?the skin isn't cut or wounded in some other way ?activated...

Whole-body MRI Takes Less Than 20 Min To Scan A Patient's Entire Body For Cancer Spread To Bone

...G-PET is superior to whole-body MRI in for staging lymph nodes, soft-tissue tumors and metastasis in the in...overed only 26. But MRI could only detect 63 of 68 lymph nodes, 15 of 19 soft-tissue tumors and 23 of 28 metastases in the internal organs, numbers below the...

Natural Killers Could Lead to New Hepatitis Treatments

...Littman. By contrast, he said, immune cells in the lymph nodes and spleen perform their surveillance ensconced within specialized compartments shielded from the turmoil of the bloodstream. “In this case, it looks like NKT cells are doing their surveillance from within the vessels,?he said. The observation...

NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma

...present at diverse sites in the body: lung, liver, lymph nodes, brain and skin. Eight other patients demonstrated a mixed or minor response. Of the 18 patients showing improvement, 15 had a partial response that lasted from two months to more than two years. It is noteworthy that there were three (9 percen...

New tool reveals secrets of migrating cells

...on in many types of tissue, ranging from nerves to lymph nodes. To date, such long-range migrations have be... thymus and distributed via the bloodstream to the lymph nodes, whence they move into the body's tissues. Her first use of two-photon imaging three years ago...

Compound might defeat African sleeping sickness, clinical trial beginning this month

...n to human by tsetse fly bites. It produces fever, lymph nodes inflammation, eventual impairment of the brain and nervous system in its late stage and, if not treated, death. The World Health Organization has estimated that more then 300,000 people are infected, and more than 60 million living in the regio...

Discovery of T-cell 'traffic control' boosts new drug promise

...rols the trafficking of T cells through the blood, lymph nodes and on to tissues to fight infection -- a cr...ling. They slow the flood of T cells "called into" lymph nodes by chemokines. The scientists made a second discovery about T cell movement: S1P, like chemok...

'Underground' tunnels discovered as means for communication between immune system cells

...aptured antigens to reach other dendritic cells in lymph nodes, increasing the number of these cells capable of stimulating T lymphocytes," added Dr. Salter. The finding that nanotubules play a role in sending molecular signals to other immune system cells calls into question the long-held belief that imm...

Researchers discover why melanoma is so malignant

...to migrate through a patient's body into, say, the lymph nodes. This phenomenon isn't related to cancer, but rather demonstrates the latent ability of melanocytes to travel Finally, the research team found that when Slug was knocked out in melanoma cells, the cancer was unable to metastasize when placed i...

Magnetic probe successfully tracks implanted cells in cancer patients

...ed to accurately guide injection of the cells into lymph nodes in half of the patients," says Bulte, an aut...reatment, however, is whether the cells get to the lymph nodes, where the immune system's fighters are normally "trained" by dendritic cells. Until now, ther...

Scientists observe how a close bond activates the immune system

...ens and present these to T cells for review in the lymph nodes. It is a demanding job. "Just 10 dendritic cells can show viral antigens to over a million T cells in a day," says Dr. Dustin. Once a T cell's antigen receptor finds an antigen match, the T cell forms an immunological synapse with a dendritic...

PET imaging reveals the immune system at work

...heir experiments Witte's group was able to see the lymph nodes, which resided at some distance from the tumor, spring into action. Lymph nodes are a critical part of the immune system, helping to recruit key disease-fighting immune cells. "This lets us see not only how but where" the body is responding to...

Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method

...heir experiments Witte's group was able to see the lymph nodes, which resided at some distance from the tumor, spring into action. Lymph nodes are a critical part of the immune system, helping to recruit key disease-fighting immune cells. "This lets us see not only how but where" the body is responding to...

New evidence supports century-old theory of cancer spread

...s macrophages, including the ability to migrate to lymph nodes and distant organs and to form a new blood supply. Our data indicate that they do this by hybridizing with macrophages," said lead author John Pawelek, research affiliate in the Department of Dermatology at Yale School of Medicine and a member ...

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