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Tag: "lungs" at biology news

U of MN researchers turn cord blood into lung cells

...tant, a substance which allows the air sacs in the lungs to remain open, allowing air to move in and out of the sacs. The cells are also responsible for helping to repair the airway after injury. "In the future, we may be able to examine cord blood from babies who have lung diseases, such as cystic fibr...

Lungs try to repair damaged elastic fibers

The lungs of patients suffering chronic obstructive pulmonar...rease in the air sacs (alveoli) and airways of the lungs of patients suffering severe or end-stage COPD," Woods explained. "This shows that the lung may be a...

Environmental toxins may cause body's defenses to worsen lung disease

...ncipal investigator for the study. "But when the lungs experience chronic, low-level damage, we believe a...continually survey the epithelial cells lining the lungs to identify and destroy diseased cells. If the lymphocyte recognizes the tissue, Borchers explains, ...

Researchers identify new weapon to fight deadly bacterial sepsis

...ed, and it can also have disastrous effects on the lungs and kidneys, which depend on efficient blood circulation. Srivastava, lead author Ramana and their collaborators injected mice with lipopolysaccharide (LPS) to produce the conditions of severe sepsis, leading to major declines in heart function a...

Lab-on-a-chip could speed up treatment of drug-resistant pneumonia

...rst. Samples are first washed out of the patient's lungs with saline solution in a procedure called bronchoalveolar lavage. The organisms are then separated, suspended in a specially designed fluid, and pumped into the chip. Inside the chip, the bacteria flow into several different compartments -- eight...

Antibody extends life of mice with breast cancer

...r tumors and to inhibit the cancer's spread to the lungs in the animals by more than 50 percent. The antibody, named JAA-F11, targets a particular disaccharide, an antigen known as TF-Ag, which aids the adhesion and spread of certain cancer cells. While the antibody did not kill the cancer cells, it bloc...

Key to acute lung injury lies in Ang2 protein

...(hyperoxia), and the resulting excess fluid in the lungs (pulmonary edema), may be controlled by modulating levels of the angiopoietin2 (Ang2) protein, researchers at Yale School of Medicine report in the November 5 online issue of Nature Medicine. The study, which was completed in the laboratory of senio...

Antioxidant protects against lung damage in silicosis

...ause direct tissue injury), become elevated in the lungs of chronic silicosis patients and could represent ...rst to demonstrate that HO-1 is synthesized in the lungs of patients with silicosis, thus contributing to a significant elevation of serum HO-1 levels in the...

Biofuel cells without the bio cells

... The feat is the bacterial equivalent of removing lungs and coaxing the disembodied tissue to breathe. Squier and principal authors Yijia Xiong and Liang Shi, PNNL staff scientists, discovered that the proteins, outer membrane c-type cytochrome A, or OmcA, formed a dense coating on the iron-rich mineral...

Therapeutic role found for carbon monoxide

...art's right ventricle to the small arteries in the lungs -- are made up primarily of endothelial cells and smooth muscle cells. PAH develops when, for unknown reasons, the smooth muscle cells rapidly and uncontrollably proliferate, leading to "remodeling," in which blood vessel walls thicken and gradual st...

Gene therapy for hereditary lung disease advances

... antitrypsin is made in the liver and protects the lungs by counteracting inflammatory products that destroy lung tissue. But about 100,000 Americans have alpha-1 antitrypsin deficiency, according to the Miami-based Alpha-1 Foundation, a national not-for-profit organization devoted to finding a cure. In ad...

Tuberculosis: The bacillus takes refuge in adipose cells

...ulosis, people with no trace of the microbe in the lungs may develop some form of tuberculosis attacking the lungs, bones or genitals. It also suggests that isoniazid treatment, prescribed to the close friends and family of patients as a preventative measure, may in some cases not provide sufficient protec...

Steep oxygen decline halted first land colonization by Earth's sea creatures

... land," Ward said. "In the first wave the animals' lungs couldn't have been very good and when the oxygen level dropped it had to be hard for the vertebrates coming out of the water. I wonder if there is a minimum level of oxygen that has to be reached or nothing could ever have gotten out of the water." ...

Mouse study reveals new clues about virulence of 1918 influenza virus

...atic and uncontrolled immune response in the mouse lungs as early as one day following infection with the reconstructed 1918 virus," he says. A complete understanding of the host's response to the 1918 flu virus, adds Dr. Katze, requires use of a fully reconstructed virus. A fuller picture of the host im...

Clot-busting drug helps revive cardiac arrest patients

...r pulmonary embolism (blockage of an artery in the lungs that can cause heart rhythm problems). Clot-busting drugs aren't typically used in patients with cardiac arrest because of concerns that the chest compressions used during CPR could cause bleeding complications. Several small studies, however, have ...

Discovery could aid fight against cystic fibrosis infection

...disease-causing bacteria could be surviving in the lungs of chronically infected cystic fibrosis (CF) patie...cterium could be promoting its own survival in the lungs of CF patients." "This finding provides a possible drug target to fight the infection in cystic f...

Coming soon: 3-D imaging that flies 'through' and 'around' cancer

...through" and "fly-around viewing" of cancer in the lungs and colon, according to a study in the July issue ..., with 3-D CT scans, small and flat lesions in the lungs and colon are difficult to see or characterize, said Quon. "Our study takes this to another level," ...

Scientists to employ Arctic ice and polar bears to protect diversity of world's crops

...o spread out of the upper respiratory tract to the lungs or brain. "These findings are especially significant because ferrets are known to be an excellent and accurate model of influenza infection and immune response in humans," said Elena Govorkova, Ph.D., a staff scientist in the Department of Infectio...

H5N1 vaccine could be basis for life-saving stockpile

...o spread out of the upper respiratory tract to the lungs or brain. "These findings are especially significant because ferrets are known to be an excellent and accurate model of influenza infection and immune response in humans," said Elena Govorkova, Ph.D., a staff scientist in the Department of Infectio...

Viagra improves high altitude exercise performance up to 45% for some

...it would reduce the constriction of vessels in the lungs that sometimes occurs at altitude. In turn, that w...ough the heart, better transfer of oxygen from the lungs to the blood and improved oxygen delivery to working muscles. The participants, all trained cyclist...

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