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Tag: "lung" at biology news

'Trojan Horse' agent halts bone metastasis in mice

...cancers in bones such as breast, multiple myeloma, lung and renal cell. "Many tumors invade bone in the same way, so these findings suggest it may be possible to shut down this process regardless of the tumor type," says the study's lead author, Michael G. Rosenblum, Ph.D., professor in the Department ...

Key to acute lung injury lies in Ang2 protein

Acute lung injury caused by cell death, high and potentially ...at Yale, looked at the response to hyperoxic acute lung injury (HALI), first in mice and then in human adults and babies. The team found that mice in which ...

Plant-derived molecules, genetic manipulation point to future chemoprevention methods

.... Trterpenoids and the rexinoid LG100268 prevent lung tumors induced by vinyl carbamate in strain A/J mi...rated their effectiveness in slowing the growth of lung cancer tumors, a research team from Dartmouth University has found. Following up on previous wor...

Antibody extends life of mice with breast cancer

...overall incidence of spontaneous metastasis to the lung -- 88 percent to 47 percent -- and fewer macroscopic metastatic lesions." The research group currently is determining if JAA-F11 could increase the effectiveness of existing cancer drugs, she said, as well as studying the possibility of using...

Key to lung cancer chemo resistance revealed

...causes chemotherapy resistance in a common form of lung cancer. Products made by a gene called NRF2 norm...es products that stop this cleansing process. But lung cancer cells sabotage the expression of these same genes to block assault from chemotherapy drugs. ...

Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses

...ve new treatments for these airway diseases of the lung and nose," says Lane. New therapies are needed, he says, as an alternative to long-term steroids, which block the inflammatory chemical pathway but also have debilitating side effects, including loss of bone density, cataracts in the eye and weight...

Environmental toxins may cause body's defenses to worsen lung disease

... to cause additional damage in people with chronic lung diseases. Michael Borchers, PhD, believes long-t...y activate a specific receptor--known as NKG2D--in lung cells that causes the immune system to attack stressed (damaged) lung tissue. "When tissue is expo...

Vaccination with embryonic stem cells prevents lung cancer in mice

...ccinating mice with embryonic stem cells prevented lung cancer in those animals that had had cancer cells ...ns, such as hereditary breast and colon cancer and lung cancer caused by smoking or other environmental factors. Professor John Eaton told a news brief...

Radiation after surgery doubles survival time for some lung cancer patients

Patients with lung cancer that has spread to mediastinal lymph nodes ...f chemotherapy after surgery in 840 non-small cell lung cancer patients and found that additional chemotherapy after surgery improves overall survival in ca...

Science researchers genetically transform immune cells into tumor fighters

...at would attack more common tumors such as breast, lung and liver cancers. The technique developed by th...t make a T cell receptor that recognizes breast or lung cancer cells. With this in mind, Rosenberg and colleagues created tumor fighters by removing norm...

Preliminary study finds holographic imaging system promising for cancer treatment planning

...ix out of 12 brain cases and was better in the one lung cancer case and one breast cancer case studied. "Our study found the Perspecta Spatial 3D Display provides users complex information in a more efficient and natural way," said James Chu, PhD, professor and director of medical physics for the dep...

Lungs try to repair damaged elastic fibers

... tissue of COPD patients. Elastic fibers allow the lung to expand and contract with breathing. "We've f...stage COPD," Woods explained. "This shows that the lung may be attempting to repair itself." The finding is important because it could pave the way to de...

Proteins may predict lung transplant rejection

...ee proteins that were highly predictive of chronic lung rejection up to 20 months before the rejection occ...id. The study, "Proteomic biomarkers of chronic lung allograft rejection," was carried out by Wendt, Tereza Cervenka, Madelaine Haddican, Yan Zhang and G...

New study: Preterm birth causes one-third of all infant deaths

...ges of cerebral palsy, mental retardation, chronic lung disease, and vision and hearing loss, as well as other developmental problems. ...

Monoclonal antibody reduces exacerbations in asthmatics

... refractory asthma have also shown improvements in lung function and airway hyperresponsiveness." During the study, 13 of the 18 patients on placebo (72 percent) experienced exacerbations, as compared to only four out of 14 patients (29 percent) on infliximab therapy. All patients in the study cohort co...

U of MN researchers turn cord blood into lung cells

...d blood stem cells to differentiate into a type of lung cell. The cord blood cells differentiated into a type of lung cell called type II alveolar cells. These cells are responsible for secreting surfactant, a substan...

Cells selectively absorb short nanotubes

...than about 200 nanometers readily enter into human lung cells and so may pose an increased risk to health,...ated by length. The researchers then exposed human lung fibroblasts to solutions containing unsorted nanotubes. Regardless of the concentration levels, the ...

Breathing easy: When it comes to oxygen, a bug's life is full of it

...lso investigating the development of the mammalian lung using mice. The work is aimed at learning more about human lung diseases and developing ways to reactivate lung development to restore diseased tissue. Stefan He...

Groundbreaking Canadian asthma study

... procedures in patients who were scheduled to have lung surgery. "We saw that this particular way of treat...ma is a common disease in which the airways in the lung become inflamed, excess airway mucus is produced, and airways narrow when muscles within the airway ...

Colour sensor breath test can detect lung cancer

A breath test can successfully pick up lung cancer with "moderate accuracy" even in the early ...ue chemical signature of the breath of people with lung cancer. Metabolic changes in lung cancer cells cause changes in the production and processing of ...

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