FSU biologists describe key role of signal-transcribing gene during cell cycle
...nd later life ills such as Alzheimer's, breast and lung cancer, and leukemia. "We now know that the transcription factor Cut is the key there," said Deng. Assisted by FSU graduate student and co-author Jianjun Sun, Deng conducted the study using the powerful Drosophila (fruit fly) genetic model. Over th...New possibilities for flu antiviral and vaccine research emerge from 'Spanish flu' virus
...quence information was recovered in fragments from lung autopsy materials and lung tissues from a flu victim who was buried in the Alaskan permafrost in 1918. The virus is contained...Shorter colds, milder flu may follow from newly revealed immune mechanism
...ratory virus infection than normal mice. Examining lung tissues from these CCL5-deficient mice, the resear...tosis is a protective mechanism. Death of infected lung airway lining cells, or epithelial cells, would deprive the virus of its home and protect the host a...How does Mycobacterium tuberculosis infect the lung?
...lting in two million deaths. TB is predominantly a lung disease. It is caused by a microbe called Mycobacterium tuberculosis which infects lung cells, but it is still not clear how exactly this happens. Ludovic Tailleux, Olivier Neyrolles, and ...The nude mouse tale: Omega-3 fats save the life of a terminal cancer patient
...78-year-old after D.H. was diagnosed with terminal lung cancer. "In 2000 he was told by his doctor he had only a few months to live," said Pardini, a professor of biochemistry and associate director of the Nevada Agricultural Experiment Station at the University of Nevada, Reno. "But five years later, h...Group proves it's possible to grow new lung alveoli by growing new blood vessels
...f developing bronchopulmonary dysplasia--a chronic lung disease caused by having to place the tiny infants...s for the treatment of infants with severe chronic lung disease. It seems possible that by augmenting or restoring vascular growth, overall lung growth and ...Mutations in the BRAF gene predict sensitivity to a novel class of cancer drugs
... in a minority of patients with colon, breast, and lung cancers. The findings, available in an advance onl...ials of patients with melanoma, colon, breast, and lung cancers. In addition, by re-analyzing the data on more than 42,000 compounds tested by the National ...Preclinical study of a new brain tumor therapy
...s of other cancer types (such as breast cancer and lung cancer), the approach pioneered in this study may be applicable to other forms of cancer as well. ...Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned
...rosol or food may require inducing immunity in the lung and gut by a very different formulation and vaccin...ictims develop fever, nausea and abdominal pain or lung damage before dying within a few days of exposure. There is no antidote after the first few hours of...Newly identified mechanism helps explain why people of African descent are more vulnerable to TB
...ith an estimated two million people dying from the lung disease each year. TB is caused by the pathogen Mycobacterium tuberculosis, but infection does not automatically result in full-blown disease. In the U.S., minority and foreign-born populations have significantly higher rates of TB than the overall U...Chemical warfare agent detection technology used to treat lung disease
...sity of Manchester to treat hospital patients with lung disease. Dr Paul Thomas and a team of researchers...es at airports, to develop a new way of diagnosing lung disease. The microDMx TM sensor, developed by Sionex Corporation, is being used to develop a new t...Experimental TB drug effective against resistant and latent mycobacterium tuberculosis
...opulation. In the most extreme cases, part of the lung may be surgically removed. It is estimated the cost of treating a single case of MDR-TB can be as much as $250,000. What makes this drug candidate even more promising, says Parrish, is that it may be the first compound ever to treat latent tubercu...Minor mutations in avian flu virus increase chances of human infection
...fic human glycans that could serve as receptors on lung epithelial cells," Wilson said. "The effect of these mutations on the Viet04 HA increases the likelihood of binding to and infection of susceptible epithelial cells." The study was careful to note that these results reveal only one possible route f...Scientists discover basic defect in cystic fibrosis airway glands
...for bacteria to grow and leads to repeated serious lung infections. The thick, sticky mucus can also block tubes in the pancreas, preventing digestive enzymes from reaching the small intestine. The disorder results from mutations in the gene for the cystic fibrosis transmembrane conductance regulator (C...Breast implants not associated with cancer risk, study reports
... a decrease in breast cancer risk and an increased lung cancer risk, but these results likely reflect the ... Women with implants had an increased incidence of lung cancer (20 cases observed, 9.1 cases expected) and a decreased incidence of breast cancer (53 cases ...Patients now surviving once-fatal immune disease
...t the vast majority of these patients have chronic lung disease by age 15. We and other physicians were qu... of the 41 patients reported that they had chronic lung disease, and 33 indicated that they had one or more episodes of sinusitis in the preceding year. Oth...Researchers reveal lung's unique innate immune system
...Medicine outline the unique mechanism by which the lung shapes its defensive strategies against microbial ...probably designed to minimize collateral damage to lung tissue caused by unchecked inflammation," said Eyal Raz, M.D., Professor of Medicine at UCSD School ...Single microRNA causes cancer in transgenic mouse
...ted a poorer prognosis in patients with breast and lung cancers. Croce, along with Dr. Stefan Costinean , a research associate, decided to isolate miR155 function by inserting the gene, along with an enhancer, to promote its expression, into fertilized eggs inside a pregnant mouse. The researchers then ...Basic research leads to a novel cancer therapy
...ageal cancer, head and neck tumours, liver cancer, lung cancer, melanoma, ovarian cancer, pancreatic cancer, prostate cancer, and testicular cancer. The studies are in various stages of clinical trials (phases I through III), and most of them are being carried out in combination with other therapies. Ull...Exposure to volcanic mineral associated with increased mesothelioma incidence in Turkey
...is form of cancer mainly affects the lining of the lung and was the cause of 44.5% of all deaths in the two villages with erionite exposure. Only two cases of mesothelioma occurred in the control village, both in people born outside of the control village. The mortality data were analyzed jointly with Ph...