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Tag: "lung" at biology news

Device traps, disables harmful bacteria

...ad become ill with hypersensitivity pneumonitis, a lung condition that mimics pneumonia symptoms. This forced the pool to shut down. It is now reopened. Lars T. Angenent, Ph.D., Washington University assistant professor of chemical engineering, and the Colorado engineers mounted three high-efficiency par...

Researchers identify genes associated with lung transplant rejection

...itive, and more accurate standard test for chronic lung rejection, as well as greater understanding of the...t it is believed to be related to rejection of the lung by the recipient's body. "For lung transplant patients, the biggest barrier to long-term survival i...

Naturally occurring asbestos linked to lung cancer

...scientists when passive smoking was found to cause lung cancer. "Like smoking, exposure to asbestos appears to be very dose-dependent," Beckett said. "Day-in, day-out occupational exposures are more dangerous than intermittent exposures in the community. But the more you can do to reduce your personal exp...

Can two killers make a cure?

...lop an effective form of gene therapy to treat the lung problems of people with cystic fibrosis. The condi... high enough proportion of cells to restore normal lung function. While HIV is good at adding genes to cells' genomes, it does not target lung epithelial c...

Two designer drugs hit same lung cancer target, but only one is effective

...to shut down a mutant, overactive growth signal in lung cancer cells, reports a team headed by scientists ...receptor) molecule, only gefitinib (Iressa) killed lung cancer cells containing a mutated EGFR molecule. The monoclonal antibody drug cetuximab (Erbitux) ha...

Researchers develop gene therapy to reverse pulmonary arterial hypertension

...is also heavily expressed in both human and animal lung arteries with PAH. Survivin is an inhibitor of apo..., Survivin drives excessive cell growth in the PAH lung blood vessels. "The most intriguing aspect," explains principal researcher Evangelos Michelakis, "i...

Researchers Discover Gene That Determines Asthma Susceptibility By Regulating Inflammation

...ing to swell and restrict. ROS is thought to cause lung tissue damage as well. ROS levels are normally off...is led researchers to consider the role of Nrf2 in lung inflammatory diseases caused by exposure to allergens. They found that the absence of the Nrf2 gene ...

Emerging staph strains found to be increasingly deadly and deceptive

...e is necrotizing pneumonia, where bacteria destroy lung tissue. "The reason that some mild infections become severe or fatal is not well understood, but virulence is often associated with certain strains," says Jovanka Voyich, Ph.D., of RML, the study's lead author. To cause human disease, bacterial path...

Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy

...ells in both groups. More importantly, cardiac and lung muscle cells in both newborn- and adult-treated hamsters were able to express the normal protein almost a year later. There were dramatic biochemical and structural improvements in muscle cells in both groups as well. This was accompanied by markedl...

Minimally Invasive Cancer Treatments Highlighted

...ng focus on treatments for liver, kidney, bone and lung tumors. The second half of the meeting provides an...r Treatments (Wednesday, November 30) By the time lung cancer becomes symptomatic, 85 percent of patients are incurable, often due to serious coexisting he...

Smoking damages key regulatory enzyme in the lung

...many compounds that affect blood pressure, and the lung is a major metabolic organ in degrading some of th...g, bladder, esophageal and throat cancers; chronic lung diseases; and coronary heart and cardiovascular diseases. Fowler and her colleagues have been study...

New factor implicated in allergy and asthma attacks

...f inflammatory cells, a downstream event common to lung and other type of allergic inflammations. By contrast, ragweed pollen extract from which NADPH oxidase had been removed produced no reactive oxygen species, and resulted in a much smaller increase in numbers of inflammatory immune cells. "We showed ...

Building a better mouse model of lung cancer: FHIT counts

...est genetic changes involved in the development of lung cancer and have incorporated them into a new strai...s that could be offered at the very first signs of lung cancer, when the possibility of a cure is most likely. Creating the new mouse was basically a matte...

Restoring silenced suppressor gene kills lung-cancer cells

...y suggests that restoring a gene often silenced in lung cancer causes the cells to self-destruct. The find..., which is lost or silenced in a large majority of lung cancers, and in cancers of the breast, ovary, prostate, bladder, esophagus and pancreas. The work wa...

Breath of the dragon: ERS-2 and Envisat reveal impact of economic growth on China's air quality

...ogen dioxide in large quantities is known to cause lung damage and respiratory problems, although little is known about the consequences of long term exposure to elevated atmospheric amounts. The presence of this gas is a significant driver of the production of low-level ozone, which, within the troposphe...

A little telomerase isn't enough

...ted grandmother developed gray hair in her 20s and lung problems in her early 60s and died at age 65. Her affected children developed signs of the disease about 10 years earlier than she had, and analysis of their cells revealed that 60 percent to 75 percent of their chromosomes had dangerously short telo...

Pillows - a hot bed of fungal spores

...bed could be problematic. It can also get into the lung cavities created by tuberculosis which affects a third of the world's population, causing general ill-health and bleeding in the lung, as well as causing a range of plant and animal diseases. Dr Geoffrey Scott, Chairman of the Fungal Research Trust...

Scientists determine structure of enzyme that disrupts bacterial virulence

... which often forms opportunistic infections on the lung surfaces of patients with cystic fibrosis, rely on their quorum-sensing systems to increase their pathogenicity and resistance to antibiotics. ...

Dangerous tricksters: Some bacterie use immune cells to reproduce

...ns is Rhodococcus equi. This bacterium can cause a lung disease in young foals which is very similar to tuberculosis in humans. Hence, it is not too surprising that Rhodococcus equi is closely related to the tubercle bacillus (Mycobacterium tuberculosis). Since macrophages are the main target of Rhodococ...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

...ast, bladder, colon, cervical, brain, melanoma and lung cancers. Since the nanocomplex systemically targets both primary tumors and metastases, this technology can also deliver contrast agents directly to the tumor to improve detection, as well as tumor resolution and definition. ...

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