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Tag: "lung" at biology news

Association of herpesvirus with lung disorder questioned

...ed the presence of the virus in similar samples of lung tissue from a similar number of patients. Both ...s. They looked for evidence of HHV-8 in samples of lung tissue from 10 patients diagnosed with primary pulmonary hypertension at a Tokyo hospital from 1981 ...

Novel antiviral technology inhibits RSV infection in mice

...05 issue ofthe journal Nature Medicine.RSV infects lung cells and can be life-threatening in very youngchi..., showed significantly lower levels ofvirus in the lung and less airway inflammation and hyper-reactivitythan untreated mice....

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

...th a larger gene expression analysis of 600stage I lung adenocarcinomas, with the hopes of confirming a previousassociation between gene expression profiles and patient outcome.This project is also an example of NCI interest in developingpublic/private partnerships. Affymetrix, of Santa Clara, Calif.,cont...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...e bacteria that are taken up by macrophages in the lung and enter a dormant state ?these are the hardest to attack with drugs." ...

Leukemia Drug Breakthrough Study In New England Journal Of Medicine

...erious cancers, including leukemias and small cell lung cancer. In another finding of the same study, all the patients with the 5q deletion who became transfusion independent also went into cytogenetic remission, meaning that the chromosome abnormality disappeared. List, a professor of interdisciplinary...

Yale Scientists Find MicroRNA Regulates Ras Cancer Gene

...ied a new way that a familiar gene is regulated in lung cancer, presenting new possibilities for diagnosis...e of the most identifiable causes in some forms of lung cancer. His team has identified let-7, a natural and separately transcribed RNA that maps to a chrom...

Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

...HIV to quit smoking would be effective in reducing lung cancer in these persons." In an editorial, Eric A. Engels, M.D., and James J. Goedert, M.D., of the National Cancer Institute, revisit the history of the AIDS epidemic and how the knowledge of cancer and immune diseases has grown since it began. The...

New lab technique identifies high levels of pathogens in therapy pool

...ttendants ill with hypersensitivity pneumonitis, a lung condition that mimics pneumonia symptoms. The study was published in the March 14 issue of the Proceedings of the National Academy of Sciences. The paper was authored by Lars Angenent of Washington University; Norman Pace, Mark Hernandez and Allison...

Scientists identify molecule that regulates well-known tumor suppressor

...-1levels. DJ-1 levels were increased in cells from lung cancer patients, and DJ-1 was associated with poor prognosis. "Our results demonstrate that DJ-1 negatively regulates PTEN function, and that this cell survival control mechanism is conserved among various tissues and species. Taken together, our da...

To control germs, scientists deploy tiny agents provocateurs

...yers on implanted medical devices and cause deadly lung infections in cystic fibrosis patients. Biofilms have long baffled researchers because of their stupefying capacity to behave like a "super-organism" that vetoes the normal characteristics of a bacterial cell in favor of new group behaviors. "It's am...

Disease diagnosis, biodefense among UH chemical research projects

...reating cancer and increasing oxygen absorption in lung tissue. Czernuszewicz's research is focused on the roles of salivary nitrophorins in storing and releasing NO and binding histamine by using resonance Raman spectroscopic techniques as a probe of molecular structure. # Yuriy Fofanov, assistant profe...

PET/CT can identify new cancer lesions at early stage, allowing for prompt treatment

...n cancer and that it was superior to CT in staging lung cancer. Wahl explained that in patients with known cancer, work-ups focus on a patient's primary disease and incidental coexistence of another primary malignant lesion can be missed. "Such newly identified lesions are often of early stage and have a...

NYU and MSKCC research provides model for understanding chemically induced cancer initiation

...tween chemical DNA damage and cigarette-associated lung cancer has been called the "smoking gun." In the ...esions ultimately contribute to the development of lung and other cancers. ...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...tal predictive test currently available is whether lung cancer cells have a mutation in their epidermal growth factor receptor (EGFR), but that does not predict response to the targeted therapy in other forms of cancer, Ueno says. "We find here that as long as CDK2 is suppressed, the drug works, so devel...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...iogenic drugs have a favorable impact on colon and lung cancers,?said NCI Director Andrew C. von Eschenbach, M.D. “This study demonstrates that when patients with recurrent or metastatic breast cancer received bevacizumab in addition to their chemotherapy, the period of time that they lived with their can...

MUHC researchers make cancer target breakthrough

...cument a reduction in the growth of both colon and lung cancer tumors with inhibition of the gene. The ne...rs." Researchers found that the antisense reduced lung and colon cancer tumors in both laboratory-based tissue cultures and in mice. "Discovering that the ...

Disease progression model of pancreatic cancer developed by Penn researchers

...splayed liver metastases, and 45 percent displayed lung metastases–further emphasizing the accuracy of this model in mimicking human pancreatic cancer. To understand the progression of pancreatic cancer, Hingorani and colleagues studied cell lines derived from primary tumor and metastasized cells. From t...

Gene keeps neural cells on correct developmental path

...e insights into other diseases, such as small cell lung cancer, which mistakenly make neuronal proteins, or neurological syndromes, where neuronal proteins produced by cancers may trigger the immune cells to attack the nervous system. The study focuses on a protein called REST, which is short for RE1-sil...

Important discovery about second most fatal cancer

... most frequent cause of death due to cancer (after lung cancer) in the industrialized world. It has become clear in recent years that colorectal cancer is not a single disease but a group of diseases, each with a different cause and behaviour. The genetic basis of this new syndrome is not known but it is ...

Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage

..., they perform vital protective functions. Certain lung infections easily cleared from normal laboratory mice are a death sentence for those lacking gamma-delta T cells. Despite their clear importance in resisting disease, the processes controlling the generation of gamma-delta T cells have remained myst...

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