Access to existing medical treatments could save more lives than spending to improve the treatments
...only 60 percent of eligible patients -- the drug's lowering of mortality would have to be increased from 20 percent to 33 percent. Woolf calls this the "break-even point" and notes that it is an unrealistic goal for many treatments. The study shows that the billions invested in statins and clot-busting drugs ...ASU researchers 'wire' DNA to identify mutations
... the electrons easier to tunnel through, just like lowering a hill for a marathon runner. "The other may be a charge-hopping phenomenon, where the electrons get trapped in the DNA and then hop from the electrode to the DNA to the second electrode." The next goal of the research is to make the measurement s...Technique offers new view of dynamic biological landscape
...on" (DAmP). "The DAmP technique gave us a way of lowering the abundance of a target gene's messenger RNA while maintaining its natural regulation," said Weissman. "Most of the mRNAs in yeast have half-lives of ten minutes or so, but our alterations destabilized them to have only a half-life of a couple of m...Gene variation affects tamoxifen's benefit for breast cancer
...ed the most common genetic variant responsible for lowering the CYP2D6 enzyme, and found that women with this genetic variant were almost twice as likely to see their breast cancer return. Up to 10 percent of women inherit this genetic trait. Their findings are published in the Dec. 20 issue of The Journal o...Survival of heart patients on beta-blockers varies greatly with genetic variation
... block this interaction, slowing the heartbeat and lowering blood pressure to relieve stress on the heart. They also block impulses that can cause rhythm disturbances. "Long-term therapy with beta-blockers is standard care for heart patients," Lanfear says. "Data from patients with acute myocardial infarctio...Unraveling a stomach cancer puzzle
...ach and other cancers. "We've demonstrated that by lowering Stat3 hyperactivity we can suppress stomach cancer formation, importantly without affecting Stat3's other important roles in the body. Add to that the evidence suggesting that Stat3 is also involved in breast, head and neck, and prostate cancers, and...Team Invents Device For Weighing Individual Molecules
...dense on the bar and add their mass to it, thereby lowering its frequency. In other words, the mechanical vibrations of the now slightly-more-massive nanodevice become slightly lower in frequency--just as thicker, heavier strings on an instrument sound notes that are lower than lighter ones. Because frequenc...Survey reveals women and doctors aren't talking about HPV
... just 18 percent of women 30+. "The first step in lowering cervical cancer rates is to educate both healthcare providers and women that this cancer is nearly 100 percent preventable through the use of regular screening with the available technologies appropriate to each age group," said Wayne Shields, presid...Live vaccines more effective against horse herpes virus
...the inactivated vaccines are not very effective in lowering equine virus levels in the blood or preventing abortions caused by the virus. "Based on recent reports and our preliminary findings, many inactivated vaccines, especially when given too often, don't appear to do much good," said Osterrieder. ...Disease diagnosis, biodefense among UH chemical research projects
...nce in many areas of human health, NO is useful in lowering blood pressure, treating cancer and increasing oxygen absorption in lung tissue. Czernuszewicz's research is focused on the roles of salivary nitrophorins in storing and releasing NO and binding histamine by using resonance Raman spectroscopic techni...Stopping smallpox in its tracks: A new anti-viral approach
...ment with these erbB-1 inhibitors are effective in lowering morbidity and mortality, and boosting T cell immunity, in infected mice. In an accompanying commentary, Anthony Fauci and Mark Challberg from the National Institutes of Health point out that this approach "may serve to turn the tables on the virus b...Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
...lls take up more cholesterol from the bloodstream, lowering its concentration there. However, inhibition of reductase function by statins also limits the availability of regulatory intermediates that govern reductase activity, contributing to a major increase in active reductase that becomes progressively ha...Nanoscale Diagnostic Sets Sights on Alzheimer's
...s of patients and their loved ones, in addition to lowering health care costs." ?Sohi Rastegar ...Bone Density Recovers After Teens Stop Injected Contraceptive
... that DMPA interferes with bone mineral density by lowering levels of estrogen, a hormone that promotes bone mineral density in women. The findings appear in the February Archives of Pediatrics and Adolescent Medicine. The study was conducted by Delia Scholes, Ph.D., of the Group Health Cooperative in Seattl...New Treatment Rivals Chemotherapy For Lymphoma, Study Finds
...mplete. The most common side effect is a temporary lowering of blood counts several weeks after the treatment. There is no hair loss and nausea is rare. Results from this study are even more promising than results using Bexxar after other therapies have failed. In those studies, 70 percent of patients respon...Bird Brains Show How Trial and Error May Contribute to Learning
...ising the pitch of a certain note and another area lowering its frequency. The moment-by-moment influence of this brain region on song is a new observation, Brainard said. Next, the researchers analyzed the relationship between song and the natural neural activity of LMAN during the two types of male finch s...Tiny scaffolding allows stem cells to become working fat cells
...ion in the body, then we could keep people leaner, lowering their chances of becoming insulin-dependent, and lowering the likelihood they would develop type II diabetes," Kniss said. He also suggested that the new app......m another country. The American team went to work lowering equipment over the side to collect water samples. They analyzed water chemistry, nutrients, and microorganism diversity. Working to assist their Japanese colleagues on board both vessels, they made these measurements to characterize how the phytoplan...