Old drug shows new promise for Huntington's Disease
...in that causes changes in personality, progressive loss of memory and cognitive ability, and a characteristic uncontrolled jerking motion known as Huntington's chorea. There is no known cure or effective treatment. A person who carries the mutant Huntington's gene may pass it on unknowingly because the di...OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis
...revealed that the tremors were associated with the loss of myelin sheaths on nerve cells, very similar to the myelin loss associated with MS and other neurological diseases, as well as in premature infants. In addition, Sh...Molecular Partners Required For Appropriate Neuronal Gene Repression
...revealed that the tremors were associated with the loss of myelin sheaths on nerve cells, very similar to the myelin loss associated with MS and other neurological diseases, as well as in premature infants. In addition, Sh...Newly recognized gene mutation may reduce seeds, resurrect plants
...lated process that necessitates allowing some seed loss to conserve resources in a stressful environment without aborting all seeds, which would leave the plant with no healthy offspring." If researchers learn how to control plant embryo abortion, they may be able to increase yield by helping plants shed...A New Era Of Hope For Neglected Diseases
..., which kill around 3m people a year and cause the loss of the equivalent of 92m years' of healthy life, there are now over 60 drug research projects underway. In the PLoS Medicine analysis, which is based upon a 100-page report financed by the Wellcome Trust, Mary Moran of the London School of Economics...Purdue researchers find key to rice blast fungus
...e fungal invasion that kills rice plants or causes loss of grain. "We found that this MAP kinase controls the penetration process, which is the beginning of a signal transduction pathway," said Xu, who also was a member of an international research team that published the rice blast fungus genome in the ......amine, a leading drug in the alleviation of memory loss symptoms. The University's Manufacturing Engineering Centre is now helping a company Alzeim Ltd (supported by Glasu, the EU funded LEADER+ Programme in Powys) to develop the agricultural potential of the daffodil as a medicinal plant along with the ...New cell transplantation technique restores insulin production in diabetics
...ult in significant morbidity, causing vision loss, loss of sensation that results in severe infections, fractures and amputations, destruction of major organ function (e.g., the kidneys) and cardiovascular disease that can result in complications such as heart attacks. Both genetic and environmental facto...Gene therapy works in mice to prevent blindness that strikes boys
...na actually begins to split in the middle, causing loss of central vision - that's the vision that you need to be able to read or walk around." Scientists say the gene transfer method eventually could be applied to many eye diseases caused by single gene defects, including a host of retinal disorders. R...Master regulatory gene found that guides fate of blood-producing stem cells
...ecame mature cell types, through the induction and loss of one its subunits, NF-Ya. "When we overexpressed NF-Ya in stem cells, the stem cells produced ten- to twenty-fold more stem cells after transplantation," says Emerson. "This makes NF-Ya the prime candidate for a master-regulatory gene for multiple...Customized gene chip provides rapid detection of genetic changes in children's cancer
...ness of neuroblastoma. An important abnormality is loss of heterozygosity (LOH), the deletion of one copy ...eral blood and from the tumor, and we should see a loss of signal in the cancer," said Dr. Fortina. He noted that the researchers can simultaneously evaluat...Shade trees getting 'scorched' by plant disease
...ks in some central New Jersey communities. Current loss of value plus replacement costs for older trees af...professionals in these locations must plan for the loss of property values and high costs of replacement as shade trees in landscapes, wood lots, and golf c...Researchers learn how blood vessel cells cope with their pressure-packed job
...or a related protein called Rho kinase resulted in loss of the healthy alignment of stress fibers as well as alignment of adhesion sites where those stress fibers would attach to the cell membrane."These new results clearly show that Rho and physical stresses cooperate to produce healthy alignments of str...Prenatal exposure to marine toxin causes lasting damage
... acid. The incident led to three deaths and memory loss in several others. First detected in the U.S. on...ic shellfish poisoning, characterized by permanent loss of short-term memory. Since the discovery of domoic acid on the West Coast, officials there collec...A bug's life: Exceptional genomic stability yet rapid protein evolution in a carpenter ant mutualist
... emerging is one of genome deterioration, with the loss of many gene functions, and extreme genome stability," says Wernegreen. "This genomic stability may prevent the reacquisition of those lost functions or the evolution of new ones. In addition, rapid protein evolution seems to degrade the genes that r...Scientists characterize proteome of human cornea
...les in the cornea. Other disorders associated with loss of corneal transparency arise from cornea swelling (Fuchs' dystrophy) or thinning and change of curvature of the cornea (keratoconus)." In order to learn more about the cornea and corneal disorders, Dr. Enghild and colleagues characterized the most ...Chernobyl: The true scale of the accident
...elarus and the additional costs of energy from the loss of power from Chernobyl. The costs have created a huge drain on the budgets of the three countries involved. What were the main consequences for the local economy? Agriculture was hardest hit, with 784,320 hectares taken from production. Timber pro...Grabbing addiction by the tail
... inside a neuron, serves as a decoy to prevent the loss of glutamate receptors. Yu Tian Wang, an HHMI international research scholar, and colleagues at the University of British Columbia in Vancouver report their findings in the November 25, 2005, issue of the journal Science. In addicted rats, cell-t...Seeing the forest and the trees
...ch as disease outbreaks that result in a selective loss of large or slow-growing trees, also produced a marked decline in the forest's ability to sequester carbon. Moreover, the study concludes that forest diversity provides a measure of "biological insurance" that prevents large swings in carbon seques......us is that evolution is not always about gain; the loss of complexity can equally be an important player in evolution." ...