Tamoxifen-like drug suggests new ways to selectively block estrogen
...t preventing breast cancer, heart disease and bone loss without increasing the risk of endometrial cancer." Tamoxifen and raloxifene are the best-known members of a class of drugs known as specific estrogen receptor modulators or SERMs. These drugs mimic some effects of estrogen and block others. For exa...Chronic Sinus Infection Thought To Be Tissue Issue, Mayo Clinic Scientists Show It's Snot
...e and sinus problems characterized by stuffy nose, loss of sense of smell, postnasal drip, nasal discharge, and head and face pain lasting three months or longer. It notably decreases the quality of patients' lives, impairing physical and social functioning, vitality and general health, according to the M...NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma
...ere no treatment-related deaths in this study. The loss of white blood cells, which fight infections, led to the development of infections in seven patients. Toxicities related to the chemotherapy and administration of a high dose of IL-2 were easily managed. The results of this study prove that a combin...Major new UNC-based drinking water study suggests pregnancy fears may be overstated
...on between byproducts known as trihalomethanes and loss of pregnancy. "We think our new work should be an...he byproduct compounds might have had on pregnancy loss (miscarriage). The study uncovered no clear-cut evidence that trihalomethanes harmed women or their...UN: World in big ecological mess
...esulting in a substantial and largely irreversible loss in diversity, with some 10 to 30 per cent of the mammal, bird and amphibian species currently threatened with extinction. * Ecosystem degradation is a barrier to achieving the MDGs. In all the four plausible futures explored, scientists project prog...Stem cell treatment improves mobility after spinal cord injury
.... These studies indicate the importance of myelin loss in spinal cord injury, and illustrate one approach to treating myelin loss. Keirstead and his colleagues are currently working on other approaches using human embryonic stem cells to treat chronic injuries and other disorders of the central nervous s...Scientists discover global pattern of big fish diversity in open oceans
...indistinguishable from the rest of the ocean. The loss of diversity means that where fishermen might have once caught 10 different species in an area on average, now they catch only five. "It's not yet extinction; it's local fishing out of species," says Myers. "Where you once had a range of a species in...UI researcher studies deafness in fruit flies, humans
...ogy. Eberl says their recent work -- showing that loss of function in the Myosin VIIA gene leads to complete deafness in fruit flies -- has brought scientists one step closer to understanding how such mutations result in inner-ear abnormalities and deafness in humans. "Myosin VIIA was one of the first h...Combination therapy leads to partial recovery from spinal cord injury in rats
... cord injury. Previous studies have shown that the loss of myelin around nerve fibers contributes to the impaired function after a spinal cord injury. However, until now it has not been clear whether promoting new myelin growth in the spinal cord can reverse this damage, says Scott R. Whittemore, Ph.D., o...Genetic links could unlock clues to leading cause of blindness
...earliest stages of the disease, when severe vision loss could still be stopped. The researchers pinpointe...d, but there is no known way to reverse the vision loss it causes. Knowing more about the earliest predictors of macular degeneration could help doctors tr......ith RA exhibiting inflammation of the synovium and loss of cartilage and bone and OA exhibiting narrowing of joint space, loss of protective cartilage, and growth of bone cysts (or osteophytes). Interestingly, Wnt-7b was stron...Montreal researchers probe the genetic basis of memory
...designed to enhance memory in patients with memory loss due to illnesses such as Alzheimer's disease, where protein synthesis and memory are impaired," concludes Dr. Karim Nader. ...Scientists succeed in cloning human embryos from eggs matured in the lab
... who are infertile because of absence or premature loss of eggs or sperm. We would do this by isolating embryonic stem cell lines from cloned early embryos and driving these embryonic stem cells to develop into eggs and sperm in the laboratory." However, Mr Heindryckx warned that there was a long way to ...Biologists determine genetic blueprint of social amoeba
...uencing effort. "Specialization appears to lead to loss of genes as well as the modification of copies of old genes. As each new genome is sequenced, we learn more about the history and physiology of the progenitors and gain insight into the function of human genes." In 1989, Loomis and Kuspa, then a pos...Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005
... who are infertile because of absence or premature loss of eggs or sperm. We would do this by isolating embryonic stem cell lines from cloned early embryos and driving these embryonic stem cells to develop into eggs and sperm in the laboratory." However, Mr Heindryckx warned that there was a long way to ...Newly discovered genetic disease sheds light on body's water balance
...se other medications that generate increased water loss in the kidneys, as these can have side effects or toxicities in young children. Instead, with Feldman and pediatric endocrinology fellow Eric Huang, MD, Gitelman administered urea, a natural nitrogen compound that encourages urination by acting as an...Discoveries by UAB and Florida scientists may help transplanted organs survive longer
...okes off the blood supply, is a major cause of the loss of function in solid organ transplants. The study, carried out in rat models, also showed that a single muscular injection of the molecule, interleukin-10 (IL-10), carried in a gene delivery vector, or mechanism, could provide long-term therapeutic ...Could better mangrove habitats have spared lives in the 2004 tsunami?
...t, and in Banda Aceh, Indonesia), resulting in the loss of the natural, protective "dyke" function of mangroves in addition to the loss of other services that mangroves provide to local economies and ecosystems. Although many politician...Stem Cells to Solve the Blood Shortage Problem?
...t, and in Banda Aceh, Indonesia), resulting in the loss of the natural, protective "dyke" function of mangroves in addition to the loss of other services that mangroves provide to local economies and ecosystems. Although many politician...Attacks of King George III's madness linked to key metabolism molecule
... King George III, the British ruler blamed for the loss of the American colonies in the Revolutionary War. The mental and physical symptoms of porphyria, a rare genetic blood disease which a number of modern researchers believe plagued King George intermittently throughout his tumultuous reign, can be br...