Scientists create dual-modality microbeads to improve identification of disease biomarkers
...e and you might not see the target molecule you’re looking for, you can let the beads capture the molecules on their surface, remove them from the liquid, and then just measure the number of molecules attached to the beads," said Nie....Sunshine pill for prostate cancer in 2009
...t so sure. 'A confounding factor is that if you go looking for more cases of cancer, you will find them. But this does not give you an accurate estimate of how many people will go on to develop advanced disease. In fact death rates are going down, which means that the market for this drug is probably pretty ...Stopping plants from getting sick
...ee James Kronstad has spent almost his entire life looking for the "Achilles' heel" of these infections and to develop fungicides to stop fungi in their tracks. He spent his childhood on Oregon wheat farms and witnessed first-hand the damage that fungi can do to crops. He then went to university to learn the...Freeze! Scientists film proteins at work by freezing them at different states
...olecules worsen these illnesses, so scientists are looking for drugs to eliminate them. The enzyme studied by the team acts uniquely in bacteria and its counterpart in humans is more complex. Synthesizing an enzyme like the one studied through biomimetics is an exciting possibility for developing future ...Gene study shows three distinct groups of chimpanzees
...ing systems. On the other hand, in this study, looking at three "subspecies" of common chimpanzees, "we found significant genetic variation," said Przeworski, "but there's very little detectable difference between the populations in terms of appearance or behavior." ...Scientists uncover new target in cancer mutation puzzle
...ch group is taking the opposite approach. They are looking for ways to stop tumors by interfering with features of cancer cells dependent upon p53 and Ras mutations. For cancer to develop, several mutations must arise and collaborate within a single cell. Ras and p53 mutations are particularly dangerous, ...Severe mental retardation gene mutation identified
.... It was found only because we were systematically looking at all the genes on the X chromosome irrespective of what they do." X-linked mental retardation is severe. Some patients require total care and may not have language ability. The condition runs in families and only affects the male offspring. S...Primitive yeast yields secrets of human cholesterol and drug metabolism
... team then tracked Dap1’s counterpart in humans by looking for similar proteins in a computer database and repeated their experiments in human kidney cells engineered to lack the human version of Dap1. As in yeast, the altered human cells accumulated cholesterol precursors and died because cholesterol is ess...How to manage forests in hurricane impact zones
...tial damage to 9 theoretical stands of pine trees, looking at how each would react to hurricane wind speeds, to make recommendations for different situations. "Our simple simulation of stem breakage potential suggests that stand spacing and tree height can be manipulated to reduce risk, and provides a st...Tiny clue reveals new path toward heart disease
... siblings had early onset coronary artery disease, looking for regions of "linkage" where DNA variations appe...his finding opens up a whole new area of study for looking at risks of cardiovascular disease," said senior study investigator Jeffrey M. Vance, M.D., Ph.D., d...Bumblebee house warming -- it takes a village
... too high. Excessive heat can kill bumblebees. In looking at the incubation behavior, O'Donnell said workers vibrate wing muscles to shunt down heat to their abdomen, which is held in close contact with a comb containing the brood. "You can see them shiver to transfer the heat," he said. "Task switchi...Study of planarians offers insight into germ cell development
...sexually: It clones itself by means of fission. In looking at nanos in asexual individuals of this species, the researchers made the surprising discovery that these asexual individuals also express nanos and produce germ cells. Some other mechanism, as yet unknown, prevents these germ cells from developing i...Viral protein is an effective preventative against infection
...re or decolonize them," says Fischetti. "But I was looking for a way to see if lysins would work for secondary infections too, and John McCullers had a very nice model system." The two researchers collaborated ?Fischetti sent McCullers, a physician at St. Jude Children’s Hospital Department of Infectious ...Study finds mercury prevalent in many western fish
...but we didn't sample salmonids of that size." In looking at mercury levels in fish across the West, the most important factors "were where the fish were in the food web, and their ages," Herlihy said. "The older a fish is, the larger it is, and the more fish that it eats, the more likely it is to bioaccumu...Army research mission focused on autism
...onths he had stopped talking, interacting, or even looking at us anymore; he was in his own little world. At four years old, he had no language, was not potty trained, and was smearing (feces) on the walls. My baby had been stolen away from us." This was the reality Lyn Redwood of the National Autism Asso...Engineering the heart piece by piece
...al Heart Laboratory’s developments and is actively looking for a corporate partner to help bring the technology to market. The U-M team’s bioreactor was developed Robert Dennis, Ph.D., formerly of the U-M College of Engineering and now at the University of North Carolina. It allows up to 11 specimens of ...Reactivated gene shrinks tumors
.... In follow-up studies, the MIT researchers are looking at other types of cancer, such as epithelial (skin) cancer, in their mouse model, and they plan to see if the same approach will also work for tumor suppressors other than p53. ...Satellites shed light on global warming
...ial to greatly increase sea level, researchers are looking to the cryosphere to get a better idea of the likely scale of the impact of climate change. In addition, the melting of sea-ice will increase the amount of solar radiation that will be absorbed by ice-free polar oceans rather than reflected by ice-co...Scientists reveal structure of gateways to gene control
... the DNA molecule, but now we know we should start looking for some of them on the edges of nucleosomes," Pugh said. "We might even discover some sites that regulate genes that we didn't even know existed." ......eum counterpart, explains Barone. "The industry is looking for a versatile product that can be used for multiple markets." Plastics made from biomass are made just like petroleum-based plastics. They are cheaper to manufacture and meet or exceed most properties except for water resistance and longevity. M...