One-of-a-kind imaging probe reveals secrets useful for drug discovery
...sey said. "We thought if this technique really can look at small samples, well, a milking of a single walking stick is very small. It's worth a try." They discovered compounds not previously known to be present in these animals, as well as chemical differences in secretions from the same walking stick at...Novel experiment documents evolution of genome in near-real time
...hese genomes are moving targets. "Paleontologists look at the fossil record to study how evolution of dinosaurs and other animals occurred over millions of years, but in the case of the E. coli bacterium, new technology has given us the ability to observe evolution as it is occurring over a matter of day...Plant studies reveal how, where seeds store iron
...nt." The findings reveal how essential it is to look beyond ferritin to understand how iron is stored by plants. The researchers say the stored iron in the vacuole is a key source of iron for developing seedlings. Seedlings that do not express the VIT1 protein grow poorly when iron is limited. ...Uncovering DNA's 'sweet' secret
... you can think of. It will be almost impossible to look at all of them," Egli said. "But the big red herring of this work could be that nature never went through these other sugars. Maybe it just hit on gold (these five-carbonsugars) very early and took off from there." ...New way of tracking muscle damage from radiation
...hese techniques are powerful, non-surgical ways to look into the body and study the microscopic and biochemical changes that are occurring in each patient after radiation therapy," Krasin said. The team made 60 images of the same area, including a dynamic view of what was happening in the muscles durin...Tearing down the fungal cell wall
...rs used a wide range of experimental approaches to look in detail at the link between the function of the gene and its impact on the structure of the spore cell wall. A recently developed gene disruption method was used to generate the fungal mutants (See "New method enables gene disruption in destructive...... bone deformation in real time. Researchers could look at two length scales: on one side they observed the 100 nanometers sized fibres, and on the other, the crystallites embedded inside the fibre, which are not bigger than 2 to 4 nanometers. The critical sample preparation was developed by Max Planc...NHGRI aims to make DNA sequencing faster, more cost effective
...s program director for technology development. "We look forward to seeing which of these technologies fulfill their promise and achieve the quantum leaps that are needed to take DNA sequencing to the next level." "$1,000 Genome" Grants NHGRI's "Revolutionary Genome Sequencing Technologies" grants ha...... selection. This inspired Dernburg and Phillips to look at similar genes in the related species C. remanei and C. briggsae. Like C. elegans, C. remanei has a total of four such genes, while C. briggsae has five. All code for zinc-finger proteins, all of which are distinct from one another. "These diff...Anticipation plays a powerful role in human memory, brain study finds
...einforce old memories. "In the future, we could look for ways to dampen that arousal response in patients so that they do not evoke negative memories so easily," she adds....Comments, experts and background on the 2006 Nobel Prize in chemistry
...passing through atoms in a substance. Those images look like bundles of twisted wire. However, they provided scientists with an understanding of how transcription works on a molecular level. ...Proteins necessary for brain development found to be critical for long-term memory
...rs are important for long-term memory, then we can look at possible remedial roles they might play in diseases such as Alzheimer's and dementia." ...PET imaging shows young smokers quick benefit of quitting
...said Tamaki. "This study provided a noninvasive look at the early stages of coronary artery disease in smokers and the recovery time of coronary endothelial dysfunction after giving up cigarettes," indicated Tamaki. Coronary endothelial dysfunction occurs when the heart's blood vessels aren't flexible ...Selecting life: Scientists find new way to search for origin of life
...IMS, an arsenal of other techniques can be used to look at the details of the interactions. "What's particularly rewarding about this research is that it's an interdisciplinary effort from different areas of science--biology, chemistry and geology," reflected Hazen. "It marries them to search for an a...Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses
... The next phase of their research, he says, is to look for what triggers the anti-parasite response. However, Lane cautions that this reaction against parasites may come at the expense of the nose's ability to ward off other invaders, such as bacteria, viruses or fungi. "The epithelial cells lining...Genetic surprise confirms neglected 70-year-old evolutionary hypothesis
...determine whether this was true, Masly had only to look at chromosome #4 and find the gene on it that caus...rking on this for six years and it was starting to look like it was all for nothing. Something was all wrong. We couldn't find the gene and we were this clo...Researchers identify new weapon to fight deadly bacterial sepsis
...hat depend on this enzyme, and so it made sense to look into with regard to sepsis, which we knew was a runaway inflammatory process," Srivastava said. "We're hoping that when an aldose reductase inhibitor is approved as a drug in the U.S. -- one is already in use in Japan for diabetes, by the way -- we c...Plants give up answers in the war on bacteria
...ack scientific papers are offering a revolutionary look at the battlefield on which plant diseases are fought ?and often lost ?to bacteria. The laboratory of Sheng Yang He at Michigan State University has changed the textbook description of a plant's surface terrain and is unveiling new knowledge of how...Teenager moves video icons just by imagination
...nd adults operate. "It's exciting to be able to look at age differences and see what that tells us about the brain," said Moran, who said the team plans to test more pediatric subjects. "No one has ever seen if brain signals from children are different. We'll try to determine if teenagers have differen...Scientists explore how complex organs develop from a simple bud
...minal vesicles is included, as well as an in-depth look at the genetic and cellular interactions critical to placental development. Research on this process in mouse kidneys generated a real-time tracking procedure which has significant implications for genetic manipulation. Ultimately, scientists hope...