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Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription

...al PLoS ONE. "These findings challenge the way we look at DNA," says Stoynov. "Until now we have pretty much simplified our view of DNA helix as a Lego combination of four different pieces, which encodes genetic information and contain patterns, recognized by DNA binding proteins. However, nucleic acids ...

Using brain scans, researchers find evidence for a two-stage model of human perceptual learning

...person had never seen faces before, they would all look similar at first." In the first experiment, the participants looked at series of cars presented at different parts of the screen and performed simple position judgments on the images, while their brain activity was being measured using an advanced...

Study to explore using magnets to correct 'sunken chest'

...lage pulls the breastbone inward, making the chest look caved in or sunken. The condition occurs in about one in 800 children born in the United States each year and is three times more common in boys than girls. A UCSF team developed the new procedure, in which a magnet attached to the child's breastb...

What's in the water? Estrogenic activity documented in fish caught in Pittsburgh's rivers

...reatest amount of cell growth. "We decided to look at pisciverous fish, those that eat other fish, for this project because we know that they bioaccumulate contaminants from water and their prey, which may include toxic metals, farm and industrial runoff and wastes from aging municipal sewer systems,...

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...ears since the study began. "The trial was a look at the toxicity and feasibility of using a dendritic cell-based vaccine against pancreatic cancer," said Andrew Lepisto, Ph.D, post-doctoral researcher in the University of Pittsburgh’s Department of Immunology. "While we are unlikely to run large-sc...

Does God answer prayer? ASU research says 'yes'

...arch suggests otherwise. This study enables us to look at the big picture. When the effects of prayer are averaged across all 17 studies, controlling for differences in sample sizes, a net positive effect for the prayer group is produced. “This is the most thorough and all-inclusive study of its kind ...

World's largest flower evolved from family of much tinier blooms

...d, meaning that to determine its lineage we had to look at other parts of the plant's genome." Davis and his colleagues determined that over an estimated 46 million years, rafflesia's blooms, which now weigh up to 15 lbs., evolved at an accelerated pace. However, after increasing in size by a factor of ...

Large size crucial for Amazon forest reserves

...cause the forest is spatially diverse. "What might look like a vast mantle of homogeneous green is actually a multicolored mosaic", said Lovejoy. And species that occur throughout the forest at the large scale actually may have very specific requirements at the fine scale. Large areas of forest encompa...

White blood cells in lung produce histamine seen in allergies

..."Nonetheless, antihistamines may deserve more of a look as therapeutic options in lung and airway infection." He says the study also has implications for other types of airway infection "in which there are a lot of white blood cells –?cystic fibrosis, for example, which can be associated with asthma-lik...

DNA ends: Common tool, different job

... the natural ends of chromosomes could potentially look like broken strands of DNA that a cell's repair machinery is designed to fix. This has been a long-standing puzzle, because mending chromosome ends as though they were double-strand breaks would result in either unregulated degradation or end-to-end ...

Prenatal cocaine's lasting cellular effects

...cocaine." "The current study was an attempt to look at the mechanism of this decrease in D1 receptor signaling," he said. Stanwood examined the levels of D1 receptor in brain cells taken from "teenage" rabbits that were exposed to cocaine during that short, sensitive prenatal period. He found ...

Biologists prove critical step in membrane fusion

...s membrane. What about the membranes? What do they look like before vesicle cargo is released? Wessel and his collaborators discovered that the membranes of the egg and the vesicles are hemifused ?a state where the membranes are shared but the contents remain separate. Using fluorescent dyes and a high...

Racing neurons control whether we stop or go

.... In those experiments, the monkeys were taught to look at a visual target unless a stop signal came on, i... in the periphery that the subject was supposed to look at. This is when the ‘go?unit was activated. Sometimes a ‘stop?signal came on and the subject had t...

Scientists to track impact of Asian dust and pollution on clouds, weather, climate change

...scientists to screen thousands of genes at once to look for clusters of genes that may be involved in disease. Although there are many approaches to studying how different nerve cells in the brain react to stimuli from the environment, this mouse model is the first to be able to provide real-time mappi...

Antarctic warming to reduce animals at base of ecosystem, shift some penguin populations southward

...f the three American bases in Antarctica . "It you look at the last 100 years or so, things have been warming in the valleys. We have seen lake levels rise, more melt from the surrounding glaciers and more aquatic ecosystems replacing soil-based ecosystems." Lyons sees what is happening now looking si...

Common algae helps illustrate mammalian brain electrical circuitry

...scientists to screen thousands of genes at once to look for clusters of genes that may be involved in disease. Although there are many approaches to studying how different nerve cells in the brain react to stimuli from the environment, this mouse model is the first to be able to provide real-time mappi...

Scientists discover a new risk factor for Alzheimer's

...contribute to disease. "Now we need to go back and look in the regions around the clusters of SNPs that we tracked and see if we can find additional genetic changes that are either unique or enriched in the individuals with Alzheimer's," said St George-Hyslop. "Then we'll have the actual genetic variation...

Rewarding fat rats

...ls tick, certain computer scientists and engineers look to the natural world for inspiration and guidance as they build intelligent machines. Ongoing research has already produced some computer programs and robots that can learn from experience and adapt their behaviour to a complex, constantly changing e...

New cigarette designs don't offer lower predicted cancer risks

...there are carcinogens in tobacco smoke, but if you look at the levels in conventional cigarettes and expected potency of those known carcinogens, and you add up all the predicted carcinogen activity, you don't come close to what's observed for the smoking-related lung cancer rate in the population," he sa...

Napoleon's mysterious death unmasked, UT Southwestern researcher says

...ncers. They determined that no benign cancer could look like the lesion described in the autopsy. "It was a huge mass from the entrance of his stomach to the exit. It was at least 10 centimeters long. Size alone suggests the lesion was cancer," Dr. Genta said. They then used a state-of-the-art tumor...

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