Beyond the book: Software automates access to brain atlases
...sulting. Page turning means that researchers can't look at two or three or five images side by side or on top of each other." Work started on the original NeuARt project ten years ago as part of the USC Human Brain Project (led by Michael Arbib who has appointments in computer science, biomedical engi...Pair of microRNA molecules controls major oncogene in most common leukemia
...e groups of cells studied, Pekarsky said. "You can look at the miRNA profile and say whether the cancer is aggressive or indolent," he said. And of the two miRNAs, miR-29 offers the most predictive power, Pekarsky added. "We have a lot of work to do to characterize these miRNAs because we don’t even kn...Innovative movies show real-time immune-cell activity within tumors
...ental Medicine. "We've taken the first real-time look at the final phase of the immune system's response to cancer cells," says Wolfgang Weninger, M.D., an assistant professor in the Immunology Program at Wistar and senior author on the new study. "This has enabled us to delineate the rules of T cell mi...Professors to develop hand-held pathogen testing device
...r detection. Hashsham's device will be designed to look for such marker genes. "This technology is rugged and highly parallel; it can analyze lots of marker genes in a lot of samples, together with significantly lower false positives," Hashsham said. He said the hand-held testing device could be use...Quality not quantity important for immune response to HIV
...e with a spectrum of CTC responses, we may need to look at a more targeted vaccine."...Cigarette smoking impedes tendon-to-bone healing
...it's still too early to tell. "We would have to look much more closely to learn exactly what the mechanism is, but blood supply is a potential culprit," she says. "Nicotine and cigarette smoking inhibit the formation of new blood vessels, and basically, all healing and all repair processes are aided by...Changing length of days reverses how estrogen affects aggressiveness in mice
... humans, but this study suggests research needs to look more at the role of estrogen receptors in some parts of the brain, Nelson said. Also, scientists are very interested in understanding how estrogen works at the molecular level in humans, especially its role in promoting cancer. "A lot of the re...History-hunting geneticists can still follow familiar trail
... and how they moved around the world. "When you look at ancient migration, you're always asking the que... "From a conservation perspective, when scientists look at census counts of animals and how the population size may be increasing or decreasing, the study o...Coral reefs are increasingly vulnerable to angry oceans
..." said Connolly. "To predict how coral reefs will look under different future scenarios, and to plan accordingly, we needed to know exactly how wave forces impact who lives and who dies on the reef. These new models provide us with that essential tool." ...PLoS ONE is launched by the Public Library of Science
...ature a public resource. PLoS has taken a close look at the way scientific and medical publishing works now, and has asked how the Internet can be used to make it work better. As a result, virtually everything about PLoS ONE is new: the peer-review strategy, the production workflow, the author experien...Buildup of damaged DNA in cells drives aging
...tern of their progeroid mice to normal old mice to look for other similarities. What they found was a striking similarity pattern between the progeroid and normal-aged mice in several key pathways. Indeed, for genes that influence the growth hormone pathway, there was a greater than 95 percent correlat...Contrary to common wisdom, scientist discovers some mammals can smell objects under water
...all kinds of semi-aquatic animals to take a closer look at how they are using their noses underwater. ...Recurrence of a flu pandemic similar to infamous 1918 flu could kill 62 million
...ies occurred in the developed world. "But when you look at the data," said Murray, "that number shrinks to about three or four percent." The disparities between the developed and developing worlds during this period are striking. For example, in Denmark 0.2 percent of the population succumbed to the fl...New biologic treatment for tennis elbow may replace surgery for chronic sufferers
...person suffering from tennis elbow may not have to look any further than his or her own body for the most effective treatment, according to a study published in the November issue of The American Journal of Sports Medicine. Specially-prepared platelets taken from the patient which are then re-injected in...St. Jude finds clues to hearing loss from chemotherapy
...hearing loss in these models, we can work back and look for specific mutations in these animals," Zuo said. "That will let us link specific mutations to specific disruptions in the ear that cause hearing loss. The long-term goal is to try to manipulate or replace those genes in order to overcome those pro...Ecstasy can harm the brains of first-time users
...mful to the brain, according to the first study to look at the neurotoxic effects of low doses of the recreational drug in new ecstasy users. The findings were presented today at the annual meeting of the Radiological Society of North America (RSNA). “We found a decrease in blood circulation in some area...Stormy days ahead for coral reefs
...says Dr Connolly. "To predict how coral reefs will look under different future scenarios, and to plan accordingly, we needed to know exactly how wave forces impact who lives and who dies on the reef. These new models provide us with that essential tool." ...How many genes does it take to learn? Lessons from sea slugs
...ics of a marine snail have gotten an unprecedented look at brain mechanisms, discovering that the neural processes in even a simple sea creature are far from sluggish. At any given time within just a single brain cell of sea slug known as Aplysia, more than 10,000 genes are active, according to scienti...USC team reveals structure of APOBEC family protein
...yze a similar chemical reaction, we expected it to look more like a square. But instead, it resembles a butterfly," Chen said. "It's significant because this non-canonical, butterfly shape provides new, plausible explanations of an immune deficiency disease at the molecular level." With the Apo2 struct......s a few months ago," says Brose. The first results look most promising - neuroligin-4 mutant mice obviously have disturbed social and anxiety behaviour. "If we succeed in measuring robust, autism-relevant behavioural changes in our mutant mice, then at least the step to experimental diagnosis and therapy ...