Army research mission focused on autism
...tion after infection. He stopped eating and was no longer happy and playful. By 17 months he had stopped talking, interacting, or even looking at us anymore; he was in his own little world. At four years old, he had no language, was not potty trained, and was smearing (feces) on the walls. My baby had been ...Engineering the heart piece by piece
...s treatment in cell cultures ?and promise over the longer term as a source of new patient treatments. As part of the effort to make the leap from the lab to the clinic, U-M is applying for patent protection on the Artificial Heart Laboratory’s developments and is actively looking for a corporate partner ...Fish can determine their social rank by observation alone, study finds
...ival first and stayed near him for a significantly longer period of time. In the AE tests, bystanders preferred E, the wimpiest of all the losers, over A, the top fish in the tank. In the more subtle BD tests, most bystanders chose D over B, even though these two rivals were ranked very close together on th...Reactivated gene shrinks tumors
...ate of senescence, or no growth. Those tumors took longer to shrink but the senescent tumor cells were eventually cleared away. The researchers are not sure why these two cancers are affected in different ways, but they have started trying to figure it out by identifying the other genes that are activate...Cancer scientists create 'human' leukemia process to map how disease begins, progresses
...emed to change as the human leukemia was grown for longer times in a series of transplanted mice. Our findings of how these leukemic stem cells functioned could explain several features of the leukemia in children and adults that also contain the same leukemia gene, MLL-ENL." In 1994, Dr. Dick identified...Drug treatment improves learning in mice with Down syndrome symptoms, Stanford/Packard study shows
... who cautions that this new ability may decay over longer periods of time as older, drug-experienced neurons are replaced by younger cells. The researchers believe that the key to the improvement lies in the fact that PTZ blocks the action of an inhibitory neurotransmitter called GABA. Normal brains main...Growth hormone to boost athletic performance risks diabetes
... His symptoms completely cleared up, and he was no longer diabetic. The use of growth hormone has steadily risen among amateur athletes and bodybuilders all round the world, say the authors, because it is easy to buy online and difficult to detect in screening tests—unlike anabolic steroids. The autho...Coated nanoparticles solve sticky drug-delivery problem
...hey can release greater amounts of medicine over a longer period of time. "We wanted to make the particles as large as possible," said Hanes, who also serves as director of therapeutics for the Institute for NanoBioTechnology at Johns Hopkins. "The shocking thing was how fast the particles that were 500 nan...Widely used iron nanoparticles exhibit toxic effects on neuronal cells
...sions called neurites, which are hundreds of times longer than the width of the cell, or up to several millimeters in length. These properties of PC12 cells have made them useful for studying the neurobiological and neurochemical properties of nerve cells. Jin and the other co-authors of the paper, Thoma...'Exercise pill' switches on gene that tells cells to burn fat
...ormal mice. Because they were able to run an hour longer than a normal mouse, they were dubbed "marathon mice." Subsequent work in the Evans laboratory found that activation of PPAR-d in these mice also suppresses the inflammatory response associated with arthrosclerosis. But the genetic metabolic ...Overfishing large sharks impacts entire marine ecosystem, shrinks shellfish supply
...e east coast of the U.S., meaning that they can no longer perform their ecosystem role as top predators," says Baum. "The extent of the declines shouldn't be a surprise considering how heavily large sharks have been fished in recent decades to meet the growing worldwide demand for shark fins and meat." ...Cells selectively absorb short nanotubes
...otubes of controlled length. They found that tubes longer than about 200 nanometers were excluded from the c...lls and remained in solution. Cells exposed to the longer nanotube solutions did not undergo a decrease in metabolic activity, but cells exposed to nanotubes ...Light wine intake is associated with longer life expectancy in men
...iovascular and all-cause death risk, but also with longer life expectancy at age 50," said Martinette T. Str...e expectancy of wine users was more than two years longer than users of other alcoholic beverages. Men with a long-term alcohol intake less than or equal to ...New fMRI technology making brain tumor surgery safer
...g takes approximately 75 minutes, about 30 minutes longer than traditional MRI. The DTI scan, which takes five minutes, is performed in the same setting. Dr. Leach processes those images, highlighting the location of speech and movement areas and white matter tracts. He also highlights the tumor location......ills some brain cells right away, others take much longer to die. If the stroke triggered a calcium-calpain feedback loop, treatment with decoy peptides might save some cells, Baudry said. His group plans to test the treatment in a stroke model in mice....New study aims to stop sepsis in its tracks
... well. Only when the blood pressure drops or is no longer responsive to intravenous fluids does the team realize it is suddenly behind the eight ball. By then, the patient is quickly spiraling into multisystem organ failure. Starting resuscitation at this point may already be too late." To test ways of ma...Early-stage immune system control of HIV may depend on inherited factors
...iously identified in people who stay healthy for a longer period of time after initial infection were associated with a more powerful early-stage HIV-specific CD8 activity. "While we can't say this for sure right now, it is looking like both the HLA Class I molecule and the specific viral sequences bein...Signal protein shows promise for blocking tumor promoters in skin cells
...ll," says Seykora. "If Srcasm is low, Fyn persists longer and sends more growth-promoting signals." Reversing Tumors Eventually, Srcasm might play a role in targeted gene therapies for cancers that are triggered by activated Src kinases. Such a therapy would likely use an adenovirus to carry a gene tha...Unique gene regulation gives chilly bugs survival advantage at bottom of the world
...to four days at the higher temperature ?four times longer than the adults. "The adults were considerably less heat-tolerant than the larvae," Denlinger said. "The larval midges continuously express heat-shock proteins and are therefore prepared to respond to the normal kinds of challenges that they face i...Evolution of Old World fruit flies on three continents mirrors climate change
...ent, to a warming climate. However, organisms with longer intervals between new generations, humans or sequoia trees for example, probably can't adapt nearly as readily. "We humans are relatively lucky that we have technology that can help us to deal with the changes. The flies can adapt very quickly. We...