Double triumph in stem cell quest
...y age and sex. "This is an enormous stride in the long journey to determine whether nuclear-transfer-derived human embryonic stem cells might be eventually suitable for transplantation medicine," says Gerald Schatten of the University of Pittsburgh School of Medicine, the only non-Korean member of the te...At long last, scientists figure out how plants grow
...That we've all been trying to figure it out for so long makes this latest discovery very satisfying." Estelle said the finding is important for basic plant science, but may also lead to new insight into how related proteins function in animals, including humans. In a 2001 report (also in Nature), Estell...One gene links newborn neurons with those that die in diseases such as Alzheimer's
...s, a kind of songbird native to Australia that has long been used in studies of birdsong. Since replaceable neurons sit side-by-side with neurons that are not replaced, the first step was to label the two kinds of cells in order to tell them apart. The replaceable neurons send projections to another part...Oceans more vulnerable to agricultural runoff than previously thought, study finds
Researchers have long suspected that fertilizer runoff from big farms ca...which can shut down mussel and clam harvesting for long periods of time. Another concern is hypoxia, or oxygen depletion, caused by excessive algae growth....Study reveals dramatic difference between breast cancers in US and Africa
... of many standard therapies. "We have known for a long time that breast cancer is not one disease and that it may be somehow different in Africa," said study author Funmi Olopade, M.D., professor of medicine and director of the Center for Clinical Cancer Genetics at the University of Chicago. "But there ...UCSD research reveals mechanism involved with type of fatal epilepsy
...of Lafora disease patients. Thus, researchers have long thought that a defect in glycogen metabolism is intimately linked to the disease. Recessive mutations in two genes have been shown to cause Lafora disease. The genes encode the proteins laforin and malin, but the molecular mechanism defining how loss...NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
... mice developed cancer. "To us this means that as long as an animal can activate the p21 gene, this can have an overriding affect on suppressing tumor formation caused by either loss of other tumor suppressor genes or diet," says Yang. "We are testing this concept further, including exactly how the p21 g...Doctors closer to using gene analysis to help trauma patients
...ety of more than $200 billion. Patients may face a long and difficult recovery period riddled with many potentially fatal complications along the way. “What we have shown is medical professionals can collect blood and tissue samples from patients, process them at different institutions and get consistent...Red delicious, Northern Spy apples have most antioxidants, chemists find
...ld’s largest scientific society. Researchers have long known that apples are a good source of antioxidants, a group of chemicals that scavenge and neutralize unstable molecules called free radicals. Free radicals, which can wreak havoc on cells and tissues, appear to play a role in the onset of heart dis...To sea or not to sea: When it comes to salmon sex, size sometimes doesn't matter
...onal male stays put and matures when only 6 inches long ?that is, he's able to fertilize eggs at even that diminutive size, says Thomas P. Quinn, University of Washington professor of aquatic and fishery sciences and author of a recently released book, "The Behavior and Ecology of Pacific Salmon and Trout...Taking the piste out of Alpine vegetation
...d pistes. And, say the researchers, this damage is long lasting. They found pistes that had been machine graded as long as 30 years ago and re-sown with plant seed had still not recovered. "Machine grading constitutes th...Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol
...forms of cancer, Ueno says. "We find here that as long as CDK2 is suppressed, the drug works, so developing an accurate test for CDK2 activity would be a boon for delivering individualized therapy to patients," he says. Such a test, however, will require that patients be given the drug for a short period...Signs of aging: Scientists evaluate genes associated with longevity
... extended lives, persisting approximately twice as long as their wild-type counterparts. Daf-2 was first reported as a critical aging-associated gene in 1993, but since that time, scientists have identified dozens of additional genes that are crucial for longevity. "Aging is a complex process," explains ...Supercomputers to focus brains on AIDS dilemma
...mutants. The new drug possibilities flow out of a long series of molecular dynamics simulations by McCammon's group. These simulations have focused on the catalytic domain of HIV-1 integrase, and relied on the large-scale computational resources of the San Diego Supercomputer Center (SDSC) at UC San Dieg...Man-made wetland's effectiveness similar to natural marsh
...r years to come. But the jury is still out on how long a wetland can remain a sink for certain nutrients, Mitsch said. For example, phosphorus doesn't degrade, so after 30 or 40 years, the wetland in this study could possibly become a phosphorus source. "Wetlands' capacity to store phosphorus declines w...Researchers make surprise discovery that some neurons can transmit three signals at once
...fic brain structures and neuronal networks. It has long been known that a specific receptor for glutamate,...nections, would gain access to these receptors has long puzzled researchers. But now, the Pittsburgh researchers believe they have solved some of the myster...Researchers develop assay that could be applied to drug screening
... mediated endocytosis has been controversial for a long time," Zenisek said. "We've now shown in live cells that proteins involved in actin polymerization are recruited to sites of membrane scission, and that disturbing actin polymerization with the toxin latrunculin B, a toxin found in Red Sea sponge, dr...Tendency to hair loss inherited from the mother
...us range of obscure lotions and tinctures. It has long been suspected that hereditary factors are important in causing hair loss. However, up to now it was unclear which genes are involved. The researchers in the team headed by Professor Markus Nöthen of the Life & Brain Centre of the Bonn University......Crigler-Najjar syndrome) has been completely cured long term with a single injection in an adult animal," ...viral vector itself is important because it has no long term effect. It does not become part of the genetic machinery of the cell and poses no risk of causi...... understanding cell division. DNA consists of two long strands joined together by pairs of bases. Both strands wind around each other in the form of a double helix with the base pairs acting as the 'stairs' in a staircase. The sequence of these base pairs stores genetic information. During cell division ...