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Tag: "long" at biology news

DNA Molecules Used To Assemble Nanoparticles

...ast agents and drugs, but the synthesis process is long and difficult, requiring months for each new molecule added to the dendrimer in sequential steps. And the yield of useful particles drops with each successive step of synthesis. For a paper published Jan. 21 in the journal Chemistry and Biology, U-M...

Bioartificial kidney under study at MCG

...f Health study to do just that. But no matter how long dialysis is given, it only replicates a fraction o...nd Drug Administration, it likely would be used as long as the patient is in failure. Kidneys require a lot of oxygen and energy to perform their endless t...

Wisconsin scientists grow critical nerve cells

...the Waisman Center at UW-Madison. Scientists have long believed in the therapeutic promise of embryonic stem cells with their ability to replicate indefinitely and develop into any of the 220 different types of cells and tissues in the body. But researchers have struggled to convert blank-slate embryoni...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...lurry picture," explains Harrison. "It took a very long time, and lots of computational work, to get that picture to sharpen up enough to get an answer." One of the lab's first steps will be to determine which shape of gp120 ?bound to the CD4 receptor, or unbound ?is recognized by a person's antibodies. ...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...iveness in killing other cells, E. histolytica was long considered to be a 'primitive' organism ?originati...se genes appear to be present within the genome in long arrays whose structural or functional significance is not yet known. "Clearly, this amoeba has gene...

Antarctic ice shelf retreats happened before

...th a shift in ocean currents that occurred after a long period of warmth. Whilst rising air temperatures are believed to be the primary cause of recent dramatic disintegration of ice shelves like Larsen B, the new study suggests that the ocean may play a more significant role in destroying them than previ...

Anti-bacterial additive widespread in U.S. waterways

...orable environmentalcharacteristics, which include long term persistence and potentialbioaccumulation. Triclocarban, for example, has an estimated half lifeof 1.5 years in aquatic sediments. Do the potential benefits ofantimicrobial products outweigh their known environmental and humanhealth risks? This i...

Timing is everything: First step in protein building revealed

...t the pieces of the ribosome come together,and how long it takes them to fall apart under various circumstances.Their results support the idea that two separate steps take place oncethe instruction's starting point is found: first a structural change inthe ribosome complex, and then release of eIF1.Lorsch...

Plants, animals share molecular growth mechanisms

...ules along a pathway that leads to the creation of long protein strings, called actin filaments, that are necessary for cellular growth, said Dan Szymanski, agronomy associate professor and lead author of the study. Knowledge of the biochemical reactions involved in this process eventually may allow resea...

The secret to longevity in tubeworms

...t ?in the form of sulfide - to keep going for this long has been a mystery. In a paper just published in the premier open-access online journal PLoS Biology, Erik Cordes and colleagues now provide a solution: by releasing its waste sulfate not up into the ocean but down into the sediments, L. luymesi stim...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

...abs "have a high degree of reproducibility , as long as standardized protocols are carefully followed"....croarrays have a high degree ofreproducibility, as long as standardized protocols are carefullyfollowed,?said Jacobson. These promising results will allow t...

Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates

...e DA neurons to surviveand for that survival to be long lasting in order to render thisapproach as a useful therapy in humans.Langston highlights that "clearly the study reported here will advanceresearch aimed at validating the use of stem cells to treatneurodegenerative disease" and this is most welcome...

New Technique for Tracking Gene Regulators

... be too labor-intensive,expensive, and take a very long time.Scientists have been working on short cuts, but all so far have limits.For example, in one recent technique, scientists mix the regulatorprotein of interest (let’s say, CREB) with the entire genome of a celland let it bind. Then they fragment th...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

... by following their patients more closely over the long term, and by looking specifically for heart rhythm irregularities in vulnerable individuals. They encourage physicians to be especially thorough when performing medical exams, and in taking patient histories to be alert for signs of heart rhythm dist...

U-M scientist to talk about tissue engineering at AAAS

...lays a leading role in the effort. Dentists have a long tradition of finding ways to fill tooth cavities that will not heal on their own, Krebsbach said, and that has led to research in biomaterials, bone and connective tissue function, and then tissue engineering. At Michigan, tissue engineering collabo...

Novel Enzyme Shows Potential As An Anti-HIV Target

... to a molecule or protein. Histone acetylation was long thought to influence transcription by regulating the structure and function of chromatin, which is an assembly of proteins (mostly histones) and DNA. Another, more widely accepted model proposes that histone acetylation controls transcription by recr...

Live Recombinant Adenovirus Vaccine Technique Explored

...piratory infections. Oral adenovirus vaccines have long been proven to be safe and effective. The researchers believe their process for constructing a replicating live recombinant adenovirus could lead to more economical vaccines that provide longer-lasting disease protection, which would be particularly ...

The secret lives of whales

...infrasonic voices to navigate. They do this during long periods of complete darkness in the middle of the ...le is ocean basin sized —one song note is 20 miles long and can illuminate the entire basin,?he says. Clark has observed that the distribution of singers i...

Gene therapy converts dead bone graft to new, living tissue

...e the proteins continuously for up to three weeks, long enough for the body to trigger the perpetual bone remodeling response. Stem cells have also seen success in this area, but Schwarz says their appeal has waned because their handling ?keeping them alive and ready to use ?is far harder than Schwarz's v...

Researchers reveal the infectious impact of salmon farms on wild salmon

...the study area, the salmon farms are anchored in a long thin fjord. Here the wild salmon have no choice bu...ile still much smaller than your baby finger ?3 cm long ?and weighing only half a gram. "The youngest fish can be only days old when they encounter a farm,"...

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