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Tag: "loci" at biology news

'Insulator' helps silence genes in dormant herpes virus

...in both yeast and chicken, namely the yeast mating loci and chicken globin locus. To see if insulators play a role in silencing viral genes during the latent phase, Zhou and his group studied cells infected with HSV-1. The studies showed that during a latent period, the virus binds to a host protein ca...

Susceptibility to Crohn's disease -- an important new clue

...e genome for the detection of novel susceptibility loci ?fixed positions on a chromosome, such as the position of a gene. Libioulle and colleagues applied this approach to Crohn’s disease and identified the key locus on chromosome 5. Individual susceptibility to many common diseases, including Crohn’s ...

Pathway toward gene silencing described in plants

... the DNA that give rise to the siRNAs and also the loci that are modified by the siRNAs," Pikaard said. Pontes found the other half of the team located within a special nuclear compartment known as the nucleolus, long known to be the production center for ribosomes. "She got a brilliant signal in the ...

Alcoholism, smoking and genetics among Plains American Indians

...ng and smoking histories. Additionally, five COMT loci ?including Val158Met ?were genotyped. "There are three key findings," said Enoch. "One, Plains Indians have very different drinking patterns. Alcoholics drink heavily, but episodically ?yet they still meet the criteria for alcoholism." Two, she...

Dog genome sequenced

...skeletal size in dogs. A striking aspect of these loci is that they control functionally related skeletal traits. "For example," says Lark, "one of the QTL that we identified controls both pelvic size and metacarpal length, but the two traits are inversely correlated. This could represent a functional ...

Scientists fetch useful information from dog genome publications

...skeletal size in dogs. A striking aspect of these loci is that they control functionally related skeletal traits. "For example," says Lark, "one of the QTL that we identified controls both pelvic size and metacarpal length, but the two traits are inversely correlated. This could represent a functional ...

'Punctuated' evolution in the human genome

...bit strong similarity to the euchromatic ancestral loci from which they were copied. According to Eichler, the limited number of comparisons of pericentromeric regions among closely related primates suggests extraordinary dynamism, where duplication, deletion, and rearrangement of large segments of DNA oc...

Improved statistical tools reveal many linked loci

...e earlier approaches to understanding how multiple loci interact, the new technique can distinguish betwee...ifficult to distinguish whether one or both of the loci being tested are responsible for altered expression levels. This problem grows exponentially with ea...

Researchers rein in regulatory RNAs

...ix randomly chosen SAT pairs revealed that the SAT loci generated multiple transcripts of various sizes, in contrast to a single transcript that is expected under the traditional one gene-one transcript model. Furthermore, the SATs tended to be poly(A)-negative and enriched in the nucleus, which strongly ...

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