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New binding target for oncogenic viral protein

... antigen--a protein called Fbw7. The Fbw7 gene is located in a chromosomal region that is deleted in up to 30% of human tumors. "Fbw7 is itself an important tumor suppressor which makes it an attractive choice for inactivation by Large T," explained Dr. Markus Welcker, the study's first author. The researc...

New Technique for Tracking Gene Regulators

...me-binding sites for CREB, including many that are located nearknown genes. Genes identified as being regulated by CREB using thismethod include the gene responsible for causing Huntington’s disease inmice, which is important for making advances in understandingHuntington’s disease in humans, and genes that ...

Bacteria collection sheds light on urinary tract infections

...ns, dogs, water and the environment. The center is located in the Department of Veterinary Science, Penn State’s College of Agricultural Sciences, with a web site at: http://ecoli.cas.psu.edu/ Other researchers involved in this project include: Amee Manges, assistant professor, McGill University; Sherry P. ...

Mitochondrial DNA mutations play significant role in prostate cancer

...clear DNA, is foundin the hundreds of mitochondria located in the cytoplasm outside ofeach cell's nucleus. The mitochondria often are called the "powerhouse"of the cell because they produce about 90 percent of the body's energy.John A. Petros, MD, associate professor of urology and pathology atEmory Universi...

New Study from Affymetrix Laboratories Points to Changing View of How Genome Works

... transcribed; most sites of transcription were not located in areas associated with protein-coding genes. The team found many diverse kinds of RNAs transcribed from distinct regions of the genome, creating a complex pool of overlapping transcription. While the team validated many known protein-coding transc...

Taking Aim With Nanoparticle PEBBLEs

...s an added bonus, helping to show where tumors are located and how they respond to treatment. In recent experiments with a small number of rats that had a type of brain cancer called 9L-gliosarcoma, PEBBLE-based treatment significantly increased survival time. People who get that type of cancer usually live...

Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site

...onal records are featured on Profiles. The site is located at www.profiles.nlm.nih.gov. The name of Francis Crick (1916?004) is inextricably linked to the discovery of the double helix of deoxyribonucleic acid (DNA) in 1953, considered the most significant advance in biology since Darwin’s theory of evoluti...

Development of portable infectious disease detector

...ia. He came across an interesting opening at Pria, located inMenlo Park, and decided to apply. Although Pria decided that he wasn'tthe right person for the job, in their correspondence Pyle expressedpotential interest in collaborating with VIIBRE. Schaffer passed theinformation along to Wikswo, who gave Pyle...

Nano-Probes Allow an Inside Look at Cell Nuclei

...is a U.S. Department of Energy national laboratory located in Berkeley, California. It conducts unclassified scientific research and is managed by the University of California. Visit our Website at www.lbl.gov. ...

Zebrafish may hold key to understanding human nerve cell development

...em difficult to access. Haircells in zebrafish are located on the surface of their body and helpthe fish swim in groups and avoid predators."Zebrafish are a wonderful model for studying hair cell development fora number of reasons. The hair cells are exposed and can be easily seenunder the microscope in the ...

Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined

...em difficult to access. Haircells in zebrafish are located on the surface of their body and helpthe fish swim in groups and avoid predators."Zebrafish are a wonderful model for studying hair cell development fora number of reasons. The hair cells are exposed and can be easily seenunder the microscope in the ...

GenMAPP 2.0 released

...em difficult to access. Haircells in zebrafish are located on the surface of their body and helpthe fish swim in groups and avoid predators."Zebrafish are a wonderful model for studying hair cell development fora number of reasons. The hair cells are exposed and can be easily seenunder the microscope in the ...

UCLA scientists transform HIV into cancer-seeking missile

...nt down and attach to P-glycoproteins -- molecules located on the surface of many cancer cells. The UCLA team is the first to prove that modified HIV will target and bind with P-glycoproteins. "P-glycoproteins cause big problems by making the cell resistant to chemotherapy," said Chen. "They act like soccer...

X-Ray Beams And Fruit Fly 'Flight Simulator' Aid Scientists' View Of Muscle Power

...unction? Using the nation’s most brilliant X-rays, located at the Advanced Photon Source at the U.S. Department of Energy’s Argonne National Laboratory, a cardiac molecular motors expert from the University of Vermont (UVM) and colleagues from the Illinois Institute of Technology (IIT) and Caltech performed ...

UCSD team discovers specialized, rare heart stem cells in newborns

...iac progenitor cells ?rare, specialized stem cells located in the newborn heart of rats, mice and humans ?has been shown by researchers at the University of California, San Diego (UCSD) School of Medicine. The cells are capable of differentiation into fully mature heart tissue. Called isl1+ cells, these car...

Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss

...ent, vice president of engineering. Optobionics is located in Naperville, Illinois. "This is an expansion of the study of the first 10 patients completed in 2002," says study investigator Dr. Kirk Packo, who oversees the three participating sites. The sites are Johns Hopkins School of Medicine, Baltimore, E...

Ophthalmologists implant five patients with artificial silicon retina microchip

...ent, vice president of engineering. Optobionics is located in Naperville, Illinois. "This is an expansion of the study of the first 10 patients completed in 2002," says study investigator Dr. Kirk Packo, who oversees the three participating sites. The sites are Johns Hopkins School of Medicine, Baltimore, E...

LUCA technologies confirms real-time methane generation

...aken from the 110,000 acre Monument Butte oilfield located in North Eastern Utah. This site represents the latest in a series of active "GeobioreactorsTM" that Luca Technologies has identified since its first demonstration of this phenomenon in the Powder River Basin coalfields of Wyoming. Geobioreactors ar...

Surprising findings reported about iron overload

...stitute. The other HEIRS Study Field Centers were located at University of California, Irvine; London Health...d the Study, and the Study's Central Laboratory is located at the University of Minnesota in Minneapolis. At the beginning of the study in 2000, it was known ...

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

...ause the university and medical school at UCLA are located on the same campus, researchers are well positioned to compete for stem cell grant funding, Witte said. UCLA researchers have proven their skill at ushering scientific discoveries from the lab to modern medicine. Several targeted therapies were devel...

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(Date:7/9/2014)... shark species may be able to cope with the rising ... , The Arctic today is best known for its tundra ... Roughly 53 to 38 million years ago during what is ... to a huge temperate forest with brackish water, home to ... creatures, crocodiles and giant tortoises. Much of what is known ...
(Date:7/9/2014)... infections usually announce themselves with pain and fever but often ... those that are sneaky and hard to beat. Now, scientists ... form of tiny DNA pyramids. Published in the journal ... nanopyramids can flag bacteria and kill more of them than ... that some infectious pathogens can lie in wait, undetectable in ...
(Date:7/9/2014)... of a sparrow-sized fossil from China challenges the commonly ... that gained the ability to fly. The birdlike fossil ... much rather the remains of a tiny tree-climbing animal ... the Dinosaur Museum in Blanding, Utah, and Alan Feduccia ... in Springer,s Journal of Ornithology . , The ...
Breaking Biology News(10 mins):Shark teeth analysis provides detailed new look at Arctic climate change 2Shark teeth analysis provides detailed new look at Arctic climate change 3Researchers declassify dinosaurs as being the great-great-grandparents of birds 2
(Date:7/10/2014)... far outweigh the risks when children receive The Right ... Dose. However, overuse and misuse of imaging change the ... effort to ensure a national protocol is put into ... of Patient Safety , calls for the American College ... and the Centers for Medicare & Medicaid Services to ...
(Date:7/10/2014)... more severe illness and even death are likely to ... developing influenza. Now, however, a team of researchers based ... reverse the order of infection, the bacteria Streptococcus ... a bad case of the flu. , The ... described as a bacterial virulence factor, might protect macrophagesa ...
(Date:7/10/2014)... Rutgers University-Newark says the human brain operates much the ... that could provide a better understanding of schizophrenia, bipolar ... an estimated 13.6 million Americans. , In newly published ... an assistant professor at the Center for Molecular and ... a person at rest is basically the same as ...
(Date:7/10/2014)... with localized prostate cancer were more likely to ... less effective treatments and survived for shorter times ... a UCLA study has found. , The negative ... such as bias against the mentally ill, depression,s ... lack of investment in his general health and ...
(Date:7/10/2014)... are just as tempting as full-fat equivalents could ... insights into how proteins can replace fats without ... by the Engineering and Physical Sciences Research Council ... University of Edinburgh has produced modified proteins that ... mimic the behaviour of fats during food manufacture. ...
Breaking Medicine News(10 mins):Health News:Mayo Clinic calls for standardization of safe imaging protocols for children 2Health News:Bacterial colonization prior to catching the flu may protect against severe illness 2Health News:Working to loosen the grip of severe mental illness 2Health News:Depressed men with prostate cancer are diagnosed later stage, get less effective therapies 2Health News:Great tasting low-fat cheeses and cakes could soon be on the menu 2
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