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Tag: "loaded" at biology news

Growth in the sea comes down to a struggle for iron

...operated by the University of Hawaii, the ship was loaded with equipment and supplies, ready for an extended stay at sea. Its subsurface pontoon hull give it more stability in choppy seas, a benefit to Wells who normally gets seasick on these voyages. For nine days, she steamed northwest to rendezvous with...

DNA Recombination and Repair—A New Twist to RecA Function

...5'-to-3' direction once the first RecA molecule is loaded onto DNA. At the same time, ATP hydrolysis causes the release of RecA from DNA, but the exact rate of RecA dissociation is not known. Experiments suggest, however, that RecA molecules only dissociate from DNA when they are at the fiber’s 5' end, whil...

Nanoparticles offer new hope for detection and treatment

...g," Lanza says. In addition, the particles can be loaded with a wide variety of drugs that will then be directed to growing tumors. "When drug-bearing nanoparticles also contain an imaging agent, you can get a visible signal that allows you to measure how much medication got to the tumor," Lanza says. "You...

Chronic Sinus Infection Thought To Be Tissue Issue, Mayo Clinic Scientists Show It's Snot

...ions, focusing now on removing the mucus, which is loaded with toxins from the inflammatory cells, rather than the tissue during surgery. Leaving the mucus behind might predispose patients for early recurrence of the chronic sinus infection." Dr. Ponikau conducted this research along with Hirohito Kita, M....

How exactly does the brain control breathing?

...area of the brainstem (the retrofacial region) and loaded with a transmitter substance called glutamate. Their close proximity to the ventral surface of the brain allows them to sense and react to changes in the pH of the cerebrospinal fluid; this is deemed an essential property of a central chemoreceptor. ...

MIT engineers an anti-cancer smart bomb

...iltepe of MIT's Department of Chemistry. The team loaded the outer membrane of the nanocell with an anti-an...sels feeding the tumor then collapse, trapping the loaded nanoparticle in the tumor, where it slowly releases the chemotherapy. The team tested this model in...

Molecular miners find pain relief drugs from the sea

...oon styled barb (a modified tooth called a radula) loaded with toxic venom. Associate Professor Livett says there are up to 200 components in each venom and there are over 500 species of cone snail, each with a different cocktail of venom peptides. Fortunately, most cone snails hunt marine worms or other m...

DNA self-assembly used to mass-produce patterned nanostructures

...arrangement when mixed together, with the DNA loop loaded with a desired "cargo" molecule that would form the structure the researchers wished to create. In one experiment, the scientists specified 16 unique puzzle pieces that fit together as a 4x4 grid that formed a puzzle spelling the letter "D." Because ...

New evidence questions the simple link between prion proteins and madcow disease

... in the gut. Using surgically modified sheep, they loaded a small area of the gut with a fluid mixture containing 0.5 grams of scrapie infected brain containing a large amount of the disease specific variant of the PrP protein and watched how it was taken up. They saw the abnormal PrP was rapidly taken u...

Amazonian terra preta can transform poor soil into fertile

...vent global warming. That's because terra preta is loaded with so-called bio-char -- similar to charcoal. "The knowledge that we can gain from studying the Amazonian dark earths, found throughout the Amazon River region, not only teaches us how to restore degraded soils, triple crop yields and support a wi...

GPSDB, the free Gene and Protein Synonyms DataBase

...vent global warming. That's because terra preta is loaded with so-called bio-char -- similar to charcoal. "The knowledge that we can gain from studying the Amazonian dark earths, found throughout the Amazon River region, not only teaches us how to restore degraded soils, triple crop yields and support a wi...

MIT: Oceans are a major gene swap-meet for plankton

...based on the discovery that seawater is absolutely loaded with invisible microbes. In trying to understand how this microbial system works, the MIT team has focused on Prochlorococcus as a model. The team's studies are showing that all Prochlorococcus strains "are very closely related, yet they display qu...

Finding a better way to make biodiesel

...oil to create biodiesel. The particles can also be loaded with chemical gatekeepers that encourage the soybean oil to enter the channels where chemical reactions take place. The results include faster conversion to biodiesel, a catalyst that can be recycled and elimination of the wash step in the production...

Buckyballs boost antibody's chemotherapy payload

...l-shaped molecules of pure carbon that can each be loaded with several molecules of anticancer drugs like Ta...ckyballs in large numbers so multiple drugs can be loaded into a single antibody in a spontaneous manner to give the antibody-drug agent more "bang for the bu...

T cells activated to fight HIV basis for dendritic cell therapeutic vaccine

...ind the development of a novel therapeutic vaccine loaded with a patient's own souped up dendritic cells, which have been galvanized to rally other cells of the immune system in fighting the virus unique to that individual. At the XVI International AIDS Conference (AIDS 2006), University of Pittsburgh res...

Scientists solve sour taste proteins

...esence of calcium ions in the cell, the scientists loaded the cells with two calcium-sensitive fluorescent dyes -- one that glowed green when the calcium concentration was high, the other that glowed red when the concentration was low. When they added sour-tasting acids to the cells, the ion channels went ...

U-M researchers use nanoparticles to target brain cancer

... particles one-billionth of a meter in size can be loaded with high concentrations of drugs designed to kill brain cancer. What's more, these nanoparticles can be used to image and track tumors as well as destroy them, according to researchers at the University of Michigan Comprehensive Cancer Center. Rese...

Liposuctioned fat stem cells to repair bodies

...nditions." It is a complex area but one that is loaded with promise. "Everyone is talking about epigenetics," says Collas. If he has his way, people may soon be visiting plastic surgeons not just for cosmetic reasons, but for therapy. ...

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

...em consists of a plasmid gene expression cassette loaded with DNA that encodes the FUS1 protein. This is wrapped tightly in a form of cholesterol to protect it from the body's defense mechanisms. The nanoparticles accumulate mainly in the lungs, particularly in the tumors, where the genes repeatedly exp...

Dual gene therapy suppresses lung cancer in preclinical test

...rs, consists of a plasmid gene expression cassette loaded with DNA that encodes either the p53 or the FUS1 protein. This is wrapped tightly in a form of cholesterol to protect it from the body's defense mechanisms. "You can't deliver naked DNA for cancer therapy," Ji says. The nanoparticles accumulate ma...

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