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Tag: "liver" at biology news

Interaction between lymph and liver cells may affect immune response

A new study on the ability of liver cells to interact with T cells (lymph cells that p...nterscience.wiley.com/journal/hepatology . The liver possesses an unusual ability to stimulate immune tolerance, possibly due to its distinctive architec...

Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese

...ity, decreased glucose levels, healthier heart and liver tissues, are positive clinical indicators and may ...on patterns triggered by high calorie diets. Using liver tissue of five mice at 18 months of age from each group, the team performed a whole-genome microarra...

Widely used hepatitis B drug spurs HIV drug resistance

...tiretroviral drug widely used to treat hepatitis B liver infections was safe to use on its own in patients ...rst," she adds. Hepatitis B infection attacks the liver and can lead to cirrhosis, liver cancer or even death from liver failure. Entecavir, first market...

Research project tackles 'regeneration' gap

...isms." Although human organ systems such as the liver are quite capable of regeneration, the brain has only a small quantity of adult stems cells to fight disease or injuries. Similarly, the body has limited capacity to repair injured limbs or spinal cords. Regeneration researchers seek to strengthen th...

MIT device draws cells close -- but not too close -- together

... Bhatia and Hui have used the new device to study liver cells. The two found that to get liver cells to express specific liver functions, they needed to touch supporting stromal cells for 18 hour...

New test helps identify hepatitis C patients at high risk of developing cirrhosis

...s helped confirm the reliability of a new test for liver disease that is ushering in the long-promised era...ng known as cirrhosis, which in turn may result in liver cancer or liver failure. Hepatitis C infection is the most common reason people need a liver trans...

Cryoablation -- A new treatment option for some kidney tumor patients

... Mayo Clinic doctors had previous experience with liver tumor cryoablation when they added kidney tumor cryoablation in 2003. Today’s report contains the largest published results for percutaneous cryoablation patients. Mayo researchers report that not only can this technique be an alternative to surger...

Growth hormone to boost athletic performance risks diabetes

...emia) while at the gym. Tests revealed that his liver was inflamed, his kidneys were enlarged and that he had very high blood sugar. He was also dehydrated, and diagnosed with diabetes. He was given intravenous fluids and gradually increasing amounts of insulin over five days, after which he was disc...

Magic Beans -- Anti-obesity soya could help prevent diabetes

...n may be having an effect on fat metabolism in the liver and adipose tissue, reducing synthesis of new fatty acids and cholesterol. It is this metabolic effect that may explain the traditional Asian use of black soya in the treatment of diabetes. ‘The key problem in type II diabetes is impairment of insuli...

Fruit fly gene research may shed light on human disease processes

... types of cells, mirroring, for example, the way a liver cell becomes different from a blood cell. Erickson cautions that there is no direct connection between sexual development in flies and that of humans, but the logic driving their cellular and molecular processes is the same. A paper by Erickson an...

Turning a cellular sentinel into a cancer killer

...vate the p53 gene in mice, causing blood, bone and liver tumors to self destruct. The p53 protein is called...they had developed to induce an aggressive form of liver cancer in mice. Although they had inactivated p53 in the mice, they genetically engineered the mice ...

Protein found that slows hepatitis C growth in liver cells

...terferes with the ability of hepatitis C to hijack liver cells and make more copies of itself. “Our find...ment fails are at high risk for fatal cirrhosis or liver cancer. In the United States, about half of all liver cancer cases occur in people infected by hepat...

New culture method for hepatitis C virus uses primary hepatocytes and patient serum

...ts approximately 170,000,000 people worldwide. HCV liver disease, which may induce liver inflammation, cirrhosis, and/or hepatocellular carcinoma, represents the foremost reason for liver t...

Liposuctioned fat stem cells to repair bodies

...ble to re-programme adult cells to become nerve or liver cells, for example, without using embryos. Adult stem cells, such as those from fat, are thought to have more limited potential. Collas insists that the transformation is possible. The hurdle lies not with the genes but with a cell’s epigenetic s...

Buckyballs used as 'passkey' into cancer cells

...ound effective at penetrating the defenses of both liver cancer cells and neuroblastoma cells. "Neuroblastoma is the most common extracranial solid tumor in children, and it is responsible for about 15 percent of pediatric cancer deaths," said Jianhua Yang. "Our findings are significant because neurobla...

Penn researchers replace organ in adult mice using 'single-parent' stem cells

...zed egg. The researchers could then harvest fetal liver cell precursors for transplant. Ultimately, the scientists found that uniparental cells, regardless of parent of origin, were able to functionally replenish the entire blood-producing system of adult mice. The scientists were able to maintain ...

Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses

...ston (UTMB), though, these two otherwise unrelated liver viruses have one important thing in common: a tric...chondria, which are found in large numbers in each liver cell. When specialized receptor molecules detect viruses in the cell, they dock with the MAVS protei...

Researchers first to map gene that regulates adult stem cell growth

...treatment of other diseases and conditions such as liver disease, diabetes and central nervous system damage as a result of trauma or stroke. The researchers also are looking into the possible role the gene plays in transforming healthy stem cells into cancerous ones, such as in leukemia and lymphomas. I...

Putting an old drug to a new use

... nifedipine helps mobilise iron from stores in the liver and enhances its excretion into the urine," says W...els in the cell or by binding directly to DMT-1 in liver and kidney still needs to be determined. "Understanding the exact molecular mechanism underlying ...

Keeping the body in sync -- The stability of cellular clocks

...tion in the gastrointestinal tract, and changes in liver metabolism. In the tiny volume of the cell, however, the chemical environment is constantly fluctuating. How is it possible for all these cell-autonomous clocks to sustain accurate 24-hour rhythms in such a noisy environment? Using mouse fibro...

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