Chewing up a key regulator of fat synthesis keeps mice lean despite a high-fat diet
...ried foods and sweets ?increases the risk of fatty liver disease, which may eventually lead to type 2 diabe...inding is that these mice are protected from fatty liver disease, a serious problem in obese individuals with insulin resistance," says Montminy. Our body's......o cells from other tissues, ranging from brain and liver cells to the insulin-producing beta islet cells of...l in Germany led by Fred Fandrich report producing liver cells. ...Novel therapy combinations gain ground in treating hepatitis
... and often leading to more serious conditions like liver failure and even death. Several different forms o...presented. Acetaminophen as a co-factor in acute liver failure due to viral hepatitis determined by measurement of acetaminophen-protein adducts [Abstract ...Study finds that a woman's chances of having twins can be modified by diet
... factor (IGF), a protein that is released from the liver of animals -- including humans -- in response to growth hormone, circulates in the blood and makes its way into the animal's milk. IGF increases the sensitivity of the ovaries to follicle stimulating hormone, thereby increasing ovulation. Some studie...Researchers discover which organs in Antarctic fish produce antifreeze
... to be produced in the liver, since the vertebrate liver is well known as a source of secreted plasma prote...rofessor of animal biology. "It turns out that the liver has no role in the freezing avoidance in these fishes at all." Instead, antifreeze glycoproteins (A...Study details hepatitis C ability to block immune system response
...cted annually. HCV is the leading cause of chronic liver disease including hepatic fibrosis, end-stage cirr...d genes with antiviral activity are induced in the liver during HCV infection," said Francis V. Chisari, M.D., a Scripps Research professor whose laboratory ...Ultra low-dose estrogen shown safe for post-menopausal women
...tions taken in pill form are processed through the liver before they reach the bloodstream," explains Yaffe...ght that estrogen in pill form might stimulate the liver to produce substances that can lead to clotting or other adverse side effects. With a patch, you byp......ns in the body ?for example, one gene works in the liver and the other in the brain ?then "if the brain ver...nts from the brain gene might be inserted into the liver gene to reconstruct a gene similar to the normal brain gene. Capecchi speculated on a possible ex...UCSD researchers develop 'smart petri dish'
...y at UCSD who headed the research team. "Since the liver is the organ that cleans up the blood, liver cells are particularly susceptible when a toxin is introduced to the body. Pharmaceutical companies ...Movie spies on malaria parasite's sneaky behavior
...one of the parasite's sneakiest tricks--using dead liver cells to cloak and transport itself back into the ...malaria parasite as it transitioned from infecting liver cells to infecting red blood cells. During this stage of the parasite's life cycle, the classic symp...Precision biochemistry tracks DNA damage in fish
...th earlier research and revealed similar damage to liver DNA (more likely tied to the fish's food) and gill DNA (more probably reflecting pollutants in water). The results suggest that these DNA lesions, and others like them, can be used as very sensitive biomarkers to provide a direct measure of the impa...Researcher studies, treats military with 'silent disease'
...ist, which is a doctor who specializes in treating liver disease, has enrolled 90 active-duty servicemember...ilian population, causes tiny scars to form in the liver and can prevent blood from flowing freely through the liver. The disease has earned its silent reput...UCLA study finds same genes act differently in males and females
...but work at different rates. "Our findings in the liver may explain why men and women respond differently to the same drug," noted Lusis. "Studies show that aspirin is more effective at preventing heart attack in men than women. One gender may metabolize the drug faster, leaving too little of the medica...How bad is malaria anemia? It may depend on your genes
...dhood. Once in the bloodstream, plasmodium invades liver and red blood cells and makes more copies of itself. Eventually, as red cells break and free plasmodium to infect other cells, and as the body's immune system works to kill infected cells, the total number of red blood cells drops, causing anemia. ...Statins stop hepatitis C virus from replicating
...threat of the disease progressing to cirrhosis and liver cancer. Based on recent reports that one statin, lovastatin, inhibits HCV replication, researchers led by Masanori Ikeda of Okayama University in Japan, tested other statins in search of a more effective anti-HCV therapy. Using the OR6 cell culture ...MUHC announces a transplant first in Quebec
...o the MUHC. The patient received his new heart and liver during a 6-hour operation on April 14, 2006 and wa...eart transplant, was transferred to the MUHC after liver complications necessitated a complex multi-organ transplant. "The patient had waited three years for...OHSU study says stem cell 'fusion' occurs in tumors
...bone marrow, called hematopoietic stem cells, cure liver disease in mice through cell fusion rather than transdifferentiation of the transplanted stem cells. Wong acknowledges fusion is still a new concept. But it's gaining popularity as a way of explaining the molecular mechanisms that may be at work in ...Green tea and the 'Asian Paradox'
...rointestinal function, alcohol metabolism, kidney, liver and pancreatic function, protect skin and eyes and alleviate arthritis. Tea has been used in managing and preventing allergies, diabetes, bacterial and viral infections, cavities, reduce or cure diseases with an inflammatory component and improve neu......erturned the negative effects of cellular aging on liver function and overall health. An 8 percent reducti...iomarkers - chemicals and molecules present in the liver - in groups of rats. The liver, a crucial organ for maintaining good health during aging, cleans the......uld be a key component for cheaper, more effective liver cancer treatment, reports Lisa Richards in Chemist...t option, but is unsuitable for most patients, and liver tumours are very resistant to chemotherapy. The American Cancer Society estimates that 18,510 new ca...