UNC launches study of liver injury caused by drugs
...ILIN, will study patients who have suffered severe liver injury caused by prescription and over-the-counter...l be the first large-scale investigation of severe liver injury associated with drugs. Other DILIN centers along with UNC are at the University of Indiana a...Turning viruses into allies against cancer
...the thyroid gland, is being studied to treat human liver cancer cells grafted in an animal model. Scientis...d that the engineered virus seeks out and destroys liver cancer cells, leaving surrounding healthy tissue in tact. The iodine "transport" protein attached t...Disease progression model of pancreatic cancer developed by Penn researchers
...genetically modified animals, 63 percent displayed liver metastases, and 45 percent displayed lung metastases–further emphasizing the accuracy of this model in mimicking human pancreatic cancer. To understand the progression of pancreatic cancer, Hingorani and colleagues studied cell lines derived from pr...Gene therapy cures inherited liver disease in rats
...f gene-virus combination cured rats of a inherited liver disease in which lack of a gene causes the accumulation of bilirubin –which, untreated, results in jaundice and brain damage, said researchers at Baylor College of Medicine in a report in the Proceedings of the Natural Academy of Sciences. "This is ...Stem cell research - new cell lines
... and spinal cord, another which forms the guts and liver and a third which forms muscles and bones," he sai...erived from the layer which also forms the gut and liver are the holy grail for diabetes researchers," said Dr Sidhu. "That's because they are destroyed in t...Mouse with designer liver has enhanced glucose tolerance, insulin response
...erated new findings about insulin-signaling in the liver that could prove useful in understanding the patho...nline at the journal's website on April 10th. The liver plays a major role in the uptake of glucose from the bloodstream, its storage, and regulation. Insul...Future diabetes drugs may target new protein interaction
...rent activities actually come together to turn the liver into a sugar-producing factory when food is scarce...to function. In people with diabetes, however, the liver doesn't sense the incoming calories, and it keeps making glucose when it shouldn't. The researchers......rent activities actually come together to turn the liver into a sugar-producing factory when food is scarce...to function. In people with diabetes, however, the liver doesn't sense the incoming calories, and it keeps making glucose when it shouldn't. The researchers...Computational verification of protein-protein interactions by orthologous co-expression
...rent activities actually come together to turn the liver into a sugar-producing factory when food is scarce...to function. In people with diabetes, however, the liver doesn't sense the incoming calories, and it keeps making glucose when it shouldn't. The researchers...Eliminate Data Analysis Bottlenecks in Drug Discovery
...rent activities actually come together to turn the liver into a sugar-producing factory when food is scarce...to function. In people with diabetes, however, the liver doesn't sense the incoming calories, and it keeps making glucose when it shouldn't. The researchers...Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis
...ic steatohepatitis is a progressive disease of the liver of unknown etiology, characterized histologically ...ethod determines the co-expression of genes in the liver tissue sample, providing monitoring treatment regimens to check progression/regression of these live...UCLA study assesses cost-effectiveness of Hepatitis B drugs
...its, diagnostic tests and complications of chronic liver disease. Investigators based the model on average...ommon type of chronic hepatitis B -- with elevated liver enzymes but no liver cirrhosis. Investigators also took into consideration the two types of hepatiti...Young Blood Revives Aging Muscles, Stanford Researchers Find
...onnected to younger lab-mates. The cells that help liver tissue regenerate are less active in older animals, but again the cells responded more robustly when the livers in older mice were bathed in the younger blood. Clearly, something in the youthful blood revived the regenerative cells in muscle and live...Embryonic Stem Cells Treated With Growth Factor Reverse Hemophilia In Mice: UNC Researchers
...re with a growth factor and then injected into the liver reverse a form of hemophilia in mice analogous to ...he said, the PEP cells robustly engraft within the liver and were not recognized by the immune system as foreign. "Within a few weeks, PEPs became hepatocyt...While on trail of dioxin, scientists pinpoint cancer target of green tea
...e against some forms of cancer, such as breast and liver cancer, exactly how it does so has been difficult to pinpoint. The latest results make more feasible the idea of harnessing green tea's protective power. Just as people with aches and pains no longer have to chew on willow bark to receive the benefi...Natural Killers Could Lead to New Hepatitis Treatments
...nels, patrol the labyrinthine blood vessels of the liver for invaders or signs of tissue damage and demonst...onsible for the inflammation and cell death in the liver due to hepatitis. Hepatitis can be a reaction to viruses, parasites such as malaria or other infecti...Research may provide new link between soft drinks and weight gain
...tributing to the increased fat storage is that the liver metabolizes fructose differently than it does other carbohydrates. "Similar to dietary fat, fructose doesn't appear to fully trigger the hormonal systems involved in the long-term control of food intake and energy metabolism," said coauthor Dr. Have...Hopkins AIDS experts issue warning about global efforts to provide drug therapies
... criteria toward a psychological assessment. With liver transplants, patient selection was plagued by diff...ely to die. In this system, the patients getting a liver transplant were often the most likely to benefit from it, but not always in greatest medical need of......long infection, cirrhosis (scarring) of the liver, liver cancer, liver failure, and death. According to the Centers for Disease Control and Prevention, approximately 1.25 ......ade red blood cells soon after their release (from liver cells) into the bloodstream. Thus, the binding of EBA-175 to glycophorin A is a prominent target for the development of therapies to control malaria. To explore the molecular basis of the binding of EBA-175 to glycophorin A--with the rationale that ...