'Failed' experiment yields a biocontrol agent that doesn't trigger antibiotic resistance
...nign mutations persisted, although it replicated a little more frequently than a mutation-free plasmid. How could it be, he wondered, that a bacteria with both mutations could not survive? The professor surmised that when the two mutations were brought together, the plasmid carrying them became harmful by ...Natural anti-viral enzyme helps keep cancer cells alive, researchers find
...e professor of cell biology. "We found something a little bit different ?an Achilles' heel of cancer cells that's apparently broadly conserved among many types of solid tumors." Using cultured human cells, the researchers set out to study enzymes known to be involved in keeping cancer cells alive and prol...Novel pathway regulates timing of brain cell development
...cytes. Making too much of one kind of cell and too little of another at a given time could lead to brain malformations. In the October 6 issue of Cell, researchers in the Neurobiology Program at Children's Hospital Boston report discovering a new molecular pathway that influences the timing of nerve-cell pr...BC catalyst discovery promises faster, cheaper drug production
.... "The new catalyst is easy to prepare, requires little or no solvent and therefore minimizes waste, and can be used in air and can be recycled several times," Prof. Snapper added. "Together, these properties make our discovery an important one both from the theoretical as well as the practical point of v...Newly identified biomarker detects and regulates spread of brain tumors
...utcome. Low-grade tumors are slow growing and show little abnormality, whereas high-grade tumors are highly abnormal and grow and spread quickly, making treatment more difficult. Patients with highly malignant astrocytomas typically have a life expectancy of about one year even after neurosurgery, chemother...What does the public really know about HPV?
...for the vaccine or if the vaccine were provided at little or no cost. Although the majority reported having...tantially higher when the vaccine was available at little or no cost. For example, 54 percent of parents indicated that they were "very likely" or "somewhat ...Mayo researchers discover HIV dependence on a human protein
.... "It turns out that the virus needs surprisingly little p75 to integrate," says Dr. Poeschla. "Future studies will want to factor such potential potency into designs of screens for additional key cellular proteins that HIV either appropriates as partners, as in the case of p75, or schemes to evade. Quite ...Ocean seep mollusks may share evolutionary history with other deep-sea creatures
... mollusks through time, Kiel and Little also found little evidence that mass extinction events or periods of low oxygen dealt significant blows to the seep communities. Seeps may have been good shelters during these events because "they were driven by a constant source of geothermal energy," Little said. ...Detailed 3-D image catches a key regulator of neural stem cell differentiation in action
...on of stem cells into neurons in a Petri dish is a little bit like a black box and not very efficient," explains co-author Samuel Pfaff, Ph.D., a professor in the Salk's Gene Expression Laboratory, who together with co-author Gordon Gill, Ph.D., of the Departments of Medicine and Cellular and Molecular Medi...Carnegie Mellon scientists use 'green' approach to transform plastics manufacturing
... from a health perspective because they contain so little copper. However, if the target application -- such as a coating for a biomedical stent -- absolutely requires the removal of residual catalyst, companies will now have much less of it to take out, significantly lowering removal costs, according to th...From a lowly yeast, researchers divine a clue to human disease
...d genetic messages -- whether with too much or too little genetic information -- can disrupt the normal functions of cells and, in some cases, lead to disease. Sen1 mutations are likely to have similar effects in humans, says Brow. By adapting his approach, other researchers may be able to identify specif...Plants give up answers in the war on bacteria
...ar genetics. "It's very frustrating. How does this little thing do such great damage to plants?" But this summer, Maeli Melotto, a research associate, and Bill Underwood, a graduate student, in He's laboratory, shed light on the behavior of one the plant's first lines of defense against disease. Pores cal...Teenager moves video icons just by imagination
..., he wasn't moving just left and right, but just a little bit left, a little bit right," he said. Teamwork Graduate students in the Washington University School of Enginee...Finding an answer to Darwin's Dilemma
...ssils, were deposited during a time when there was little or no free oxygen in the world’s oceans," says Dr. Narbonne. "Immediately after this ice age there is evidence for a huge increase in atmospheric oxygen to at least 15 per cent of modern levels, and these sediments also contain evidence of the oldest...First Biodiversity Census of coral reef ecosystems in the NW Hawaiian Islands
...have been called "the rainforests of the sea", but little is known about the ocean's diversity as compared to its terrestrial counterpart. According to Dr. Nancy Knowlton of Scripps Institution of Oceanography at UC San Diego, CReefs lead principal investigator, "We don't even know to the nearest order...Seals protect brain, conserve oxygen by turning off shivering response on icy dives
...urs in the face of insufficient oxygen and require little time to recover, Folkow explained. Seals often spend 80-90% of their time at sea underwater, he said. Seals in the wild occasionally dive for so long that they use nearly all their oxygen, but they can recover with these special adaptations. Human...Giant insects might reign if only there was more oxygen in the air
...ned. But when they removed its apparently lifeless little body from the water, they were surprised to see it crawl away. Tracheae grow disproportionately This experiment was designed to find out: how much room the tracheal system takes up in the bodies of different-sized beetles whether tra...New system could drastically reduce herbicide use
...es it a lot more difficult." The robot stands a little more than two feet tall, is 28 inches wide and almost five feet long. He can travel about three miles per hour and moves on wheels, although the researchers have treads they can put on him as well, to give him more grip. At the current stage, the ...Developing uses for sugar-cane bagasse: Biotechnology applied to the paper industry
...tained without ethanol. Moreover, it appeared that little or no ethanol introduced was consumed by the fungus which preferentially uses other sources of carbon, resulting from the bagasse (saccharose) or put in with the substrate (maltose, yeast extracts and so on). It can therefore be recycled in the syste...... Nevertheless, they say, many women in Uganda had little power at the outset of the AIDS epidemic. "Fortunately," say Murphy and Greene, "a 'this could not work here' attitude did not deter Uganda from moving forward to implement its wide-ranging HIV prevention program and adding gender-related elements wh...