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Tag: "literature" at biology news

Newly Discovered Compound Blocks Known Cancer-Causing Protein

...y its chemical structure. A search of the chemical literature turned up no previous description of the chemical, leading the scientists to believe they had discovered a new chemical compound with a unique biological function. When the scientists tested the compound's ability to inhibit Ras function in living c...

Agilent Technologies releases automated literature search tool for biology researchers

...ologies Inc. (NYSE: A) today released an automated literature search tool for the multidisciplinary study of bio...rching for each gene and protein in the scientific literature and patents. "Mining past literature for information about proteins and protein interactions is a c...

RNA project to create language for scientists worldwide

...RNA motifs, or repeated patterns, mentioned in the literature or appearing in databases, to agree upon and write a definition for each motif. The consortium's work will be accessible on the Web to the various RNA research communities using servers hosted at BGSU. Some researchers focus on the sequences of RNA ...

Not-for-profit publishers call NIH public access rule a missed opportunity

...shers would ensure the integrity of the scientific literature while at the same time reducing the size and there...ponsible stewards of the scientific and biomedical literature for more than 100 years," Hogan said. "What we propose would expand this partnership in a way that b...

Glow-in-the-dark zebrafish at UH hold keys to biological clocks

...cal, is committed to making scientific and medical literature a public resource. "By injecting the luc gene that makes fireflies glow into our zebrafish, our bottom-line finding goes back to nature versus nurture," Cahill said. "We found that these per3-luc zebrafish contain something in their genetic makeup t...

CoPub Mapper: mining MEDLINE based on search term co-publication

...determined. To assess gene clustering according to literature co-publication, 150 genes consisting of 8 sets with known connections (same pathway, same protein complex, or same cellular localization, etc.) were run through the program. Receiver operator characteristics (ROC) analyses showed that most gene sets ...

Different microarray systems more alike than previously thought

...e Hopkins researchers noted that in the scientific literature some comparisons of different microarray systems found compatibility and some did not, and no study explored the possibility that a laboratory's methods of using a particular system affected the results. "Given the amount of tinkering that occurs in...

The evolutionary triumph of flower power

...Flowers have been ignored for the most part in the literature on plants and people," McGuire says. "Perhaps they have been overlooked because their nature and beauty is so obvious. It is hard to imagine that we might have been responsible at least in part for their appearance. With the proposed model of evoluti...

Ariadne Genomics Announces the Release of PathwayStudio?Central, Client-Server Software for Biological Pathway Analysis

...udio?Central helps scientists to keep current with literature using embedded MedScan information extraction tool that can “read?scientific text and extract functional relationships on the fly? said Ilya Mazo, President of Ariadne Genomics. “They can get an immediate view of all known relationships for a protein...

Building a protein name dictionary from full text: a machine learning term extraction approach

The majority of information in the biological literature resides in full text articles, instead of abstract...tracts remain the focus of many publicly available literature data mining tools. Most literature mining tools rely on pre-existing lexicons of biological names, o...

Asymptomatic HIV babies could use earlier treatment

...g because there’s been a lot of controversy in the literature as to whether infected but asymptomatic infants should be started on therapy right away,?said the study’s senior author Yvonne Maldonado, MD, a pediatric infectious disease expert at Lucile Packard Children’s Hospital and an associate professor of pe...

The first impact factor for PLoS Biology ?13.9

...ake the world's treasury of scientific and medical literature a public resource ?is fulfilled. We hope that PLoS Biology's first impact factor will inspire even greater support for PLoS journals and for open access. * Thomson ISI calculated the impact factors that it announced this year by counting all the cit...

Mapping neuron connections in the brain

...drawings are already available in the neuroscience literature for many types of neurons. With this method, neuron connection maps could be used to create computer simulations of neural circuits involving tens of thousands of neurons with biologically realistic connections--and provide a practical way to begin u...

Study shows how retinoic acid enters a cell's nucleus

... NLS, and it solves a mystery that has been in the literature for a long time," Noy says. "It explains a basic mechanism of how this protein, CRABP-II, gets into the nucleus, where it can act to suppress tumors." CRABP-II is a member of a group of proteins called intracellular lipid binding proteins (ILBP), wh...

Biased reporting found in cancer prognostic studies

...pelling evidence yet that the published prognostic literature is a serious distortion of the truth," write Lisa M. McShane, Ph.D., of the National Cancer Institute in Bethesda, and colleagues, in an accompanying editorial. They call for more transparent reporting, better study design, appropriate analysis metho...

Public collections of DNA and RNA sequence reach 100 gigabases

...ays when sequences were manually keyed in from the literature or sent on floppy disc and distributed to users on 9-track magnetic tapes, but the purpose of the databases - to make every nucleotide sequence in the public domain freely available to the scientific community as rapidly as possible - remains as stro...

Women cautioned against using herbal supplements

... decrease breast cancer risk. Warren reviewed the literature on herbal supplements and breast cancer risk for his report, which was reviewed by two international experts in the field as well as the five scientists on the BCERF staff. "Just because herbal medicines are 'natural' products does not mean that the...

Menopause Symptoms May Come Back After Stopping Menopausal Hormone Therapy

... decrease breast cancer risk. Warren reviewed the literature on herbal supplements and breast cancer risk for his report, which was reviewed by two international experts in the field as well as the five scientists on the BCERF staff. "Just because herbal medicines are 'natural' products does not mean that the...

'Underground' tunnels discovered as means for communication between immune system cells

...ure connecting only those cells that discharged. A literature search turned up a handful of papers describing tunneling nanotubules, and further imaging using the highest magnification possible disclosed their presence in both the dendritic cells and macrophages. In their most definitive experiment, the resear...

Computer modeling reveals hidden conversations within cells

...e Alex, who can critically evaluate the scientific literature to decide what parameters need to be included in the model, and someone like Shannon who can take the predictions of the model and design experiments to test them in the laboratory." ...

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