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Tag: "lipid" at biology news

Global analysis of membrane proteins

All cells are encased within a protective lipid membrane. The membrane is studded with many hundreds of different proteins that transport nutrients, ions, and water into and out of the cell. Such membrane proteins also help cells recognize each other in the body, and make the nervous system work. ...

Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert

...nd to one of the following ?nucleic acid, protein, lipid or carbohydrate ?all molecules of life. "We don't know of other remote methods capable both of detecting low levels of micro-organisms and visualizing high levels incorporated as biofilms or colonies," said Gregory Fisher, project imaging scientist....

Researchers discover molecular mechanism that desensitizes us to cold

...region of this receptor interacts with a signaling lipid in the cell membrane called PIP2. Cold or menthol stimulate this receptor and alter the electrical properties of the membrane, a process that leads to the sensation of cold. When the receptor is stimulated, calcium enters the cell and stimulates the ...

Opposing fat metabolism pathways triggered by a single gene

...r off a set of target genes when bound by specific lipid molecules. In the premier open-access journal PLoS...rring within two metabolic pathways: mitochondrial lipid oxidation and fatty acid desaturation. Following up on these changes in gene expression, Yamamoto a...

UCSD discovery may help extend life of natural pesticide

...ts and roundworms. The molecule is a glycolipid--a lipid attached to a tree-like arrangement of sugars. Because changes in the sugars impact Bt's ability to bind, the researchers believe that their discovery will make it possible to develop better pesticides and lead to new treatments for parasitic infecti...

New research questions basic tenet of neuron function

...be the result of differences in the protein and/or lipid composition of the vesicles," Dr. Kavalali said. "Higher-resolution analysis is needed to test whether the two sets of vesicles are indeed distinct." Dr. Kavalali said that if the two types of vesicles have different molecular compositions, as their...

Researchers Uncover Key Step In Manufacture of Memory Protein

...r. Loh said. The golgi apparatus then encases the lipid rafts ?along with proBDNF ?in bubble-like structur...hese mice, proBDNF could not be delivered into the lipid raft-rich vesicles for conversion to mBDNF. Instead, it appeared to leak out of the golgi apparatus,...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

... parts of the mechanism activate many key genes of lipid biosynthesis involving the pathways of cholesterol and triglycerides; these genes directed the liver to manufacture more cholesterol, which it does in the form of very low-density lipoproteins. The investigators noted that in mice fed high-fat diets,...

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