Anti-inflammatory drug's potentially deadly side effect found to be rare
...lizumab's effects on a patient more quickly." The links between natalizumab and PML onset are still unclear, but based on their prior dealings with the disorder, PML experts like Clifford strongly suspect an immune system connection. "As many as half of all adults are infected with the virus that causes...Novel connection found between biological clock and cancer
...ge resets the cellular circadian clock, suggesting links among circadian timing, the cycle of cell division, and the propensity for cancer. Their work, reported June 29 in Science Express, the advance electronic publication of Science, implies a protective dimension for the biological clock in addition to...Iron critical to ocean productivity, carbon uptake
...feld said the presence of iron stress in the ocean links phytoplankton to the climate through changes in terrestrial-based dust deposited in the ocean, but it is too early to tell if there is an impact of recent climate change on iron-stressed populations because the satellite data record is too short. "B...Chimpanzees can transmit cultural behavior to multiple 'generations'
...ders; and advance knowledge about the evolutionary links between biology and behavior. ...Insect predation sheds light on food web recovery after the dinosaur extinction
...s that the K-T extinction destroyed the ecological links in the food web. Plants and insects were killed ou... new host plants. As the ecosystem rebuilt new links from its shattered state, the empty ecological space was open to opportunism, and in a few places th...Mechanism identified for promising neurological drug
...California, San Francisco, explains that the study links two previous biological observations. The first is that PARP-1, a protein found in every cell, becomes activated whenever a cell's DNA is damaged. Depending on the nature and extent of the damage, PARP-1 can trigger either DNA repair, an inflammatory...On the track of tiny larvae, a new model elucidates connections in marine ecology
...tic and oceanographic models helps predict genetic links among several locations and is an important new tool for the management and ecological study of marine protected areas. ...FSU biologists uncover mechanisms that shape cells for better or worse
...The current study -- "Dystroglycan down-regulation links EGFR signaling and anterior-posterior polarity formation in the Drosophila oocyte" -- relied heavily on the state-of-the-art laser confocal microscope in FSU's Biological Science Imaging Resource facility. Funding for the research came in part from t...Researchers uncover new mechanism of tumor suppressor
... that will appear in Nature titled ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. "Our findings have established the mechanistic principles by which the inhibitor of growth 2 tumor suppressor recognizes chromatin and regulates cell growth, proliferation, stress responses ...Researchers link two more genes to sudden infant death syndrome
...ed two more cardiac genes to the list of potential links to sudden infant death syndrome (SIDS), increasing the possibility that genetic defects of the heart may cause up to 15 percent of SIDS cases. This research will be presented Friday at Heart Rhythm 2006, the 27th Annual Scientific Sessions of the Hea...New research examines genetics of successful aging
... Pittsburgh is among the first to identify genetic links to cognitive longevity. "Successful aging has been defined in many ways, however, we focused on individuals who had reached at least 90 without significant decline in mental capacity," said lead researcher George S. Zubenko, M.D., Ph.D., professor ...Large-scale genomics project will hunt genes behind common childhood diseases
...elp to set the standard for identifying biological links to childhood diseases." ...K-Staters design and build a low-cost remote sensing tool for environmental studies
...dra in Alaska," Ham said. "The earth's atmosphere links all cultures and nations. By that, I mean that carbon dioxide emitted in China, for example, can impact the vegetation in North America or Europe and vice versa. Any decisions about climate change have to be based on a complete global analysis," he s...Free radical cell death switch identified
..., have now defined how a molecular chain-of-events links oxidative-stress signals to cell death in brain neurons. In the course of investigating the mechanisms of cell death in neurons from rat brain, the team focused their attention on the function of a protein called MST, which had been previously impli...Worm links cancer risk to ageing
...tial as an area of inquiry into potential cellular links between ageing and cancer." The research, which was completed at the Buck Institute in California where Dr Lithgow now works, involved genetically removing checkpoint proteins in the microscopic worm C. elegans. By doing so, the researchers caused a...A splice of the action: Translational role for WT1 isoform
...ral impact of this study is that it highlights the links that exist between transcription and post-transcriptional gene regulation and the importance of alternative splicing. We hope that these results will stimulate further studies to identify genes that are regulated by WT1 at the translational level and...Scientists use gene signatures to match cancer and other diseases with potentially effective drugs
...tivity Map, which in its initial edition contained links to 164 different drugs and other chemical compounds, was used to obtain information on treatments for obesity, Alzheimer's disease, and cancer, and to suggest new therapies for drug-resistant leukemia and advanced prostate cancer. Scott Armstrong, ...Solvent exposure linked to birth defects in babies of male painters
... by the University of Alberta in Edmonton, Canada, links low birth weight and birth defects to paternal, airborne exposure to organic solvents such as paints, thinner and cleansers. The study, although preliminary in its parent-reported assessment of birth outcomes and small numbers of reported cases, is...Researchers add to understanding of how brain cells communicate
...memory is speculative, but I am confident that the links will become firmer as research progresses," Johnson said. ......lood sugar levels. And further into the future are links smart pumps that, when signalled, instantly deliver the correct medication. Another prediction is the use of miniature telescopes that restore vision for patients with degenerative eye disease. The telescopes are powered by sunlight passing throug...