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Study Links Ebola Outbreaks To Animal Carcasses

...d 2003 produced positive results, and found direct links between the deadly disease in animal populations and humans. "This research proves that hunting and consumption of great apes represent a serious health risk for people in Central Africa, and a risk that can be avoided," said Dr. William Karesh, fie...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

...s on the surface of the cell. The human end of GFD links to a different cell surface protein (called FcgRIIB) that interrupts the allergic response. Dr. Saxon and his colleagues first tested GFD in blood donated by people allergic to cats. They cultured blood cells with either GFD or with a purified human...

Critical role in programmed cell death identified

Dartmouth Medical School geneticists have found links in the cell death machinery of worms and mammals, opening new avenues for studying and targeting a process vital to development and implicated in cancer and autoimmune diseases. The work, reported in the February 17 issue of Nature, demonstrates the...

Research Gives Hope For Liver Damage

...ts. Researcher Dr Jeremy Duffield explained: "The links between the immunesystem, inflammation and scarring in the liver have not been wellunderstood, and this has hindered progress in finding ways to preventand repair liver damage. Now that we have shown how the macrophageswork, we aim to find out how to...

PANTHER Protein Classification System Database 5.0

...proach to protein and mRNAexpression analysis with links to biological content, informaticstools, and lab instrumentation to support systems biology research,?said Dennis A. Gilbert, Ph.D., Chief Scientific Officer for AppliedBiosystems. “Users can query the database using probe IDs from theApplied Biosyst...

Agilent Technologies releases automated literature search tool for biology researchers

...y a geometric shape for each gene and protein, and links to indicate relationships. Each node includes hyperlinks to descriptions and articles relevant to that gene or protein. Agilent Laboratories is using the plug-in as part of its collaborations with two other organizations on systems biology projects:...

Not-for-profit publishers call NIH public access rule a missed opportunity

...her Michael A. Keller. "HighWire also permits free links to over 389,000 other articles that are listed as references. Other not-for-profit publishers also offer free access." "NIH's rule is limited relative to what these not-for-profit publishers are currently doing with Google and patient groups to prov...

Advances in the characterisation of the oyster mushroom genes

...f units of D-glucose united by means of glycosidic links that form long polymer chains. The breaking down b...ubstrate: the endoglucanases attack the glycosidic links within the cellulose molecule, the cellobiohydrolases act by liberating units of cellobiose from eit...

Computational Method Speeds Mapping of Cell Signaling Networks

...d with a sophisticated communications network that links surveillance with response, and allows the cells to perform a variety of tasks--such as growing in response to hormones, moving towards a source of nutrients, or responding to foreign invaders in the body. In all of these cases, external signals are ...

Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes

...asia with aortic aneurysm reveal new evidence that links the disorder with small vessel disease, a significant cause of lacunar or "mini" strokes that can damage small areas of the brain. Depending on which area of the brain is affected, the strokes can impair functions such as movement, physical control ...

Insight into DNA's 'weakest links' may yield clues to cancer biology

...nter finds that yeast cells also contain such weak links in DNA and begins to reveal the molecular characteristics of these links that might help to explain them. The findings, published in the March 11, 2005, issue of Cell, sugg...

Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX

...ip arrays. The GeneChip Globin Reduction Protocol links PreAnalytiX' already proven standard for whole blood collection, stabilization and isolation of RNA with Affymetrix' leading product line for microarray-based analysis of whole blood cellular RNA profiles. "An accurate picture of in vivo gene expres...

Ariadne Genomics Announces the Release of PathwayStudio?Central, Client-Server Software for Biological Pathway Analysis

...s of gene expression regulation, and about 160,000 links between 1779 human diseases and individual proteins. ResNet was compiled with MedScan?unique Natural Language Processing (NLP)-based tool. MedScan?leverages hand-crafted dictionaries of protein and chemical names, and precise text parsing and patter...

Molecular messengers perform a crucial role in the ability of injured nerve cells to heal themselves

...om dismantling or loss of the phosphorus. Vimentin links up to motor proteins that carry the message along the axon, and thanks to this linkage and protection, the messengers can safely transmit their message, thus bringing the injured axon's call for help to the cell body. The study will be published in t...

Researchers reveal secret of key protein in brain and heart function

.... This domain, known as PDZ1, is where the protein links to NMDA receptors. The team used high-resolution nuclear magnetic resonance spectroscopy to solve the structure of PDZ1, as well as a small portion of the receptor to which it binds. Mierke said the group is now developing a molecule that can inhibi...

Excess liver gene protects against high-fat diet

...unrecognized role for these liver receptors in the links between diet, serum lipids, and atherosclerosis." Selective modulation of the LXR target genes in liver may therefore ameliorate high lipid levels and cardiovascular disease, the researchers said. The researchers include Michael Lehrke, Corinna Leb...

Improved statistical tools reveal many linked loci

...f genes with "joint linkage," where each gene site links to another. "In some ways, it looks like you're complicating a problem because you're looking at thousands of genes instead of one trait," says Kruglyak. In reality, the method creates statistical conclusions that are more precise, he explains, beca...

Molecular steps involved in the creation of gene-silencing microRNAs identified

... gene silencing." Intriguingly, the research also links the process of creating miRNAs with aspects of the HIV life cycle and with tumor suppression. The study identifies three proteins that work together in the cytoplasm to create finished miRNAs. Individually, each of the proteins was known previously, ...

To translate touch, the brain can quickly rearrange its sense of the body

...rpreted the signals from the sense of touch. These links between different bodily senses show that the brain constantly updates its internal map, and they shed light on the dynamic and flexible nature of the body map that is used to interpret each new perception. de Vignemont et al.: "Bodily illusions mod...

Novel plague virulence factor identified

...thogenic enterobacteria," Aballay said. "This work links for the first time this particular family of bacterial proteins to virulence and we have done so by using a C. elegans pathogenesis system and a new mouse model of plague." Aballay said that these types of conserved virulence factors may regulate in...

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