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Tag: "linking" at biology news

Gene variations explain drug dose required to control seizures

... the investigators report the first clear evidence linking variation in genes involved in the action or metabolism of the anti-epileptic drugs, carbamazepine and phenytoin, to the drugs' clinical use. The study is the first to emerge from a partnership, aimed at tailoring the treatment of epilepsy to patient...

Wiley announces publication of Databasing the Brain

...ce data types, applying them to brain research and linking them with databases within neuroscience and other fields such as genomics and proteomics. "Databasing the Brain: From Data to Knowledge (Neuroinformatics)" (Wiley; February 2005; $135.00; Paper; 0-471-30921-4) is the first book to comprehensively cov...

A new study examines how shared pathogens affect host populations

...nteractions but also provide a potential mechanism linking host biodiversity and ecosystem functioning. Sponsored by the American Society of Naturalists, The American Naturalist is a leading journal in the fields of ecology and evolutionary biology and animal behavior. For more information, please see our w...

Newly discovered pathway might help in design of cancer drugs

...ch as mitomycin c -- work: They kill off tumors by linking up with the cancer cells' DNA and sticking its genetic code together so it dies. Our discovery takes that a step further, establishing that there is a way to efficiently create this type of damage by modifying the DNA itself." In the lab, Greenberg ...

Grasping metaphors: UC San Diego research ties brain area to figures of speech

... means." Ramachandran's lab is continuing work on linking other brain areas, the supramarginal gyrus and human homologues of mirror neurons, for example, to other types of metaphoric abilities. Intriguingly, in the current study, patient KK, who had damage not only to the angular gyrus but also to the supr...

Africa to take it on chin again with climate change

...e from five computer models, provides new evidence linking drought in southern Africa to the warming of the Indian Ocean. However, it contradicts earlier studies that also connected the Sahelian drought of northern Africa to the Indian Ocean. Instead, the new results point to a late 20th-century cooling of t...

Oceans more vulnerable to agricultural runoff than previously thought, study finds

...sity scientists presents the first direct evidence linking large-scale coastal farming to massive algal blooms in the sea. Writing in the March 10 issue of the journal Nature, the authors conclude that some highly productive regions of the ocean are much more vulnerable to agricultural runoff than was previ...

Climatologists discover deep-sea secret

...er to be transported northwards. These mechanisms linking the two hemispheres had already been observed in computer climate simulations, but this is the first time they have been confirmed with detailed data obtained from scientific experiments using weather records from the past. This is the first evidence...

Self-assembled DNA buckyballs for drug delivery

...enetic codes any more. Since DNA can polymerize -- linking many molecules together into larger structures -- scientists have been using it as a nanoscale building material, constructing geometric shapes and even working mechanical devices. Now Cornell University researchers have made DNA buckyballs -- tiny ...

Unraveling a stomach cancer puzzle

...butions to the understanding of Stat3, the protein linking those 'genes behaving badly' and central to development, tissue equilibrium and the immune system. "We showed that, in mice, hyperactive Stat3 shuts down a vital controller of stomach cell growth, called TGF beta, and this allows cancer formation, an...

Attacks of King George III's madness linked to key metabolism molecule

...rs said they have provided "a clear-cut mechanism" linking fasting to an increase in PGC-1 alpha, and, in turn, overactivity of the ALAS-1 gene. The therapeutic effect of glucose and high-carbohydrate diets on porphyria, they add, occurs because glucose causes the pancreas to make more insulin, which results...

Discovery suggests why stem cells run through stop signs

...ree other new papers published this week in Nature linking microRNAs to cancer. According to authors Richard Carthew, Owen L. Coon Professor of Molecular Biology at Northwestern University, and Hannele Ruohola-Baker, professor of biochemistry at the University of Washington, microRNAs can regulate gene expr...

Rodent social behavior encoded in junk DNA

...rain. This is an extraordinary example of research linking gene variation to brain receptors to behavior." Hammock and Young were particularly intrigued with microsatellites, repeating sequences of letters in the genetic code peppered throughout these regulatory areas of the vasopressin receptor gene. "It ...

Team of international scientists departs today to discover the unknown in China's Himalayan region

... Florida. To further explore new opportunities for linking culture and environmental protection, Disney will research the legend of the yeti, a creature whose traditional role as "protector of the sacred" has been integral to preservation in this region. One of the world's hotspots, the Mountains of Southw...

New understanding of jet lag

...Virginia. Block likens GABA to a weak rubber band linking pendulums swinging at different rates. If the "rubber band" could be made stronger, such as using a drug to enhance GABA, the ventral and dorsal parts of the central timekeeper could more quickly move back into harmony. The symptoms of jet lag would ...

NYU biologists map out early stages of embryo formation

... be the case for human embryogenesis. The diagrams linking all these genes reveal discrete patterns of interconnections, allowing us to begin to visualize the molecular network underlying a complex process like early embryogenesis as a whole." These analyses suggest that out of the almost 20,000 genes in C....

Molecular trigger for Huntington's disease found

... in HD, our findings provide a molecular mechanism linking disturbances of nuclei and mitochondria in HD." Byoung-Il Bae, Shuichi Igarashi, Masahiro Fujimuro, Nishant Agrawal, Yoichi Taya, S. Diane Hayward, Timothy H Moran, Christopher A Ross, Solomon H Snyder, Akira Sawa: "p53 Mediates Cellular Dysfunction...

Molecular cabal contributes to stroke damage

...the researchers discovered the molecular mechanism linking two key components of neuronal damage due to oxygen starvation, or ischemia. One component is a type of receptor called an NMDA receptor (NMDAR). This receptor is triggered by glutamate, which is known to be released during ischemia. The other compo...

Newly discovered birdlike dinosaur is oldest raptor ever found in South America

...limbs; and bird-like pelvis--provide more evidence linking dinosaurs to birds. Buitreraptor gonzalezorum is described in the cover story of Nature October 13. It was excavated last year by a team of Argentine and American paleontologists, including Peter Makovicky, curator of dinosaurs at The Field Museum....

Science's Breakthrough of the Year: Watching evolution in action

...ging Climate of Climate Change?: In 2005, evidence linking humans to global warming continued to accumulate and U.S. politicians began to take notice. From the warming of deep ocean waters and increased frequencies of the most intense tropical cyclones to continued reductions in ice cover in the Arctic Ocean...

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