New Lab Research May Help Those Deafened By Immune System Attack
...tibody creates a staining pattern that resembles a line of tiny wine glasses when it binds to IESCA in the organs of Corti of guinea pigs. The U-M has patent applications pending in the U.S. and abroad pertaining to KHRI-3, IESCA and AISNHL. The University, Carey and several colleagues stand to profit if...Past droughts geographically widespread in the West, according to tree-ring data
... manager of Water Resource Operations. "The bottom line is that the Upper Colorado Basin and the Salt and Verde basins work together as one entire region." Tree-ring-based reconstructions of streamflow can peer back into time much further than the records available from stream-flow gauges. Ester said suc...Geckos: It's not always about sex
... in the case of the Australian Bynoe's gecko. This line of all-female geckos doesn't need sex or a male to reproduce and, contrary to expectations, these "Wonder Woman" geckos can run farther and faster than their sexually reproducing relatives. The research findings are published in the journal Physiolog...Shampoo detergent added to paint makes surfaces self-sterilizing
...k. Students who may be interested in pursuing this line of research can contact Vermeulen through his website at science-projects.com. ...Clearing jams in copy machinery
...he two strands. Polymerases then add, in assembly line fashion, nucleotide bases -- the building blocks that make up DNA -- to convert the now-single-stranded templates into two new duplex DNA molecules. The new research shows that two different DNA polymerases, the high fidelity Pol III replicase and t...Results of world's first gene therapy trial for arthritis show approach safe, feasible
...he immune cells and synovial cells, the cells that line the joint. As the researchers discovered in earlier animal studies, synovial cells have a receptor on their surface that's a perfect fit for a particular cytokine, interleukin-1, or IL-1. Like a switch, when IL-1 binds to this receptor, the cell unle...... concluded that the efflux of organics is a second line of defence, which is only activated if there are considerable problems. All organisms in the natural environment are confronted with salt balances in and around their cells. Plants, bacteria and fungi have an extra cell wall that provides the cell ...Cells direct membrane traffic by channel width
...rmal water channel. So even if glycerol molecules line up properly, as do water molecules to pass through...the other way around, by mutating amino acids that line the pore of the channel, but they have failed." The E-coli proteins studied were AqpZ, a water chan...Study: Plants use dual defense system to fight pathogens
...Ps. The PAMP pathway appears to be a plant's first line of defense against pathogenic attackers. "The PAM...trigger defensive responses." A next step in this line of work is to look at other pathogen effector proteins and analyze their role in causing infections....Genetic variation alters response to common anti-clotting drug
...er dose of warfarin to get its full benefits. This line of work ultimately could help doctors determine each patient's warfarin dose more quickly and precisely. The study, part of the NIH Pharmacogenetics Research Network, was supported by three components of the National Institutes of Health (NIH): the ...Firefly protein lets researchers monitor molecule linked to cancer
...ells only. They are currently working to develop a line of mice with the IKB/luciferase fusion built into its genetic code. In addition, they showed that the system is not only helpful for learning if a drug is having the desired effect, it can also be used to fine-tune drug dosage for maximum benefit. ...How fish hear and make sounds at same time
...the first time that scientists have found a direct line of communication between the part of a vertebrate's brain that controls the vocal muscle system and the part of the ear that hears sound. The researchers believe that understanding the auditory system of the plainfin midshipman fish (Porichthys notat...Researchers develop new testing methods for potential monkeypox or smallpox outbreak
...irus infections, and these findings are totally in line with what we expected. What this means is that there are more than 100 million people in the U.S. that have partial or even fully protective immunity that is maintained after childhood vaccinations -- an important point to consider if we were ever to...UW scientists report a new method to speed bird flu vaccine production
...articles. Vaccine makers use a monkey kidney cell line to make non-virulent viruses that serve as the raw material for vaccines.The technique reported by the Wisconsin team improves upon a previous reverse genetics method (developed by Kawaoka's group in 1999) by significantly reducing the number of plas...Tiny roundworm's telomeres help scientists to tease apart different types of aging
...dy keep dividing throughout life (e.g., those that line our digestive tract, blood, and immune cells) because they must be replaced over time. When these cells' telomeres reach a critically short length, however, they can no longer replicate. The cell's structure and function begin to fail as it enters th...Out of sight, out of mind? Not necessarily
...ntary blindness, either a horizontal or a vertical line or a red or a green dot flashed on the screen. Re... saw nothing. However, when forced to guess which line had appeared on their computer screen, the participants gave the correct answer 75 percent of the ti...U-M scientists discover identifying markers for primitive blood-forming stem cells
...close contact with cells called osteoblasts, which line the inside of hollow cavities in bone that contain bone marrow. Using SLAM markers, we discovered hematopoietic stem cells also congregate in the sinusoidal endothelium ?porous cells lining the inside of blood vessels that carry oxygen throughout bon...'License to kill' enables powerful immune attack cells in mice
...oup's research was made possible by a unique mouse line created by Ted H. Hansen, Ph.D., professor of path...versions of the MHC molecule, but Hansen created a line that makes only one. This was essential to the ability of Yokoyama's group to test its hypothesis. ...Costly breeding programs for endangered species pay off
...order animals have small broods, each fly breeding line was allowed to grow by no more than 50 percent per generation. Each time a pair of flies mated, researchers measured the fitness of the pair by counting the number of eggs the female laid, and by measuring the number of eggs that hatched. In the MA......e 2005 federal Canadian budget contained the first line item ever to target invasive species directly ?$85 million, much of which is earmarked for battling the borer and another forest pest, the Asian longhorn beetle, which has infected hardwood trees in areas around Toronto, New York and Chicago. If co...