Diabetes research takes wing thanks to long-lived fruit fly
... the body for stress by slowing its metabolism and limiting its energy output. It might also offer a new way to control insulin production. Like JNK, the insulin receptor is also involved in determining life span. Caloric restriction ?limiting the calories an organism ingests ?generally increases lifespan in...In drug design, a loose fit may be best bet
...rmone with its GPCR, activating one G-protein, and limiting its signaling ability. In future studies, the scientists hope to determine whether their findings are consistent with other hormone-GPCR reactions. Other researchers taking part in the study represent the National Institute of Pharmaceutical Educati...Carnegie Mellon researchers discover key deficiencies in brains of people with autism
...icularly in the connections to the frontal cortex, limiting what types of networks can be used," said Marcel Just, co-author of the studies and director of Carnegie Mellon's Center for Cognitive Brain Imaging. Both studies focused on people with autism who have normal IQs. In one study, the researchers used...HIV-1's high virulence might be an accident of evolution
...ty called T cells following SIV infection, thereby limiting the detrimental effects otherwise caused by chroni... carrying Nef genes artificially made incapable of limiting T cell activation might become more pathogenic in their natural monkey hosts. The group will also ex...Scientists to employ Arctic ice and polar bears to protect diversity of world's crops
...l fluid, feces, throat and blood serum. Therefore, limiting the spread of virus in an infected human is crucial to saving that person's life." Govorkova is the lead author of the JID paper and led the research team conducting the study. The team also showed that the optimal strategy for vaccination of imm...New light microscope sharpens scientists' focus
...alizing individual molecules would be as simple as limiting the amount of violet light they used to turn on the fluorescent probes, so that they turned on just a tiny percentage of the labeled molecules. The concept struck them as so obvious, in fact, that they suspected other researchers might already be...H5N1 vaccine could be basis for life-saving stockpile
...l fluid, feces, throat and blood serum. Therefore, limiting the spread of virus in an infected human is crucial to saving that person's life." Govorkova is the lead author of the JID paper and led the research team conducting the study. The team also showed that the optimal strategy for vaccination of imm...Sticky surfaces turn slippery with the flip of a molecular light switch
...se membranes, clogging up their pores and severely limiting their performance, according to Georges Belfort, the Russell Sage Professor of Chemical Engineering at Rensselaer and corresponding author of the paper. "We asked ourselves, can one use light to help the proteins hop on and hop off? We have shown th...Heart has enough oxygen to survive hypothermia, CPR crucial
...shaev and Tveita did the study "Is oxygen supply a limiting factor for survival during rewarming from profound...orking. "As a consequence, oxygen supply was not a limiting factor for survival in the present experiments," the authors wrote. The rats in the one-hour group...Ultrasound may help regrow teeth
...odontic braces causes progressive root resorption, limiting the duration that braces can be worn. This new device will work to counteract the destructive resorptive process while allowing for the continued wearing of corrective braces. With approximately five million people in North America presently wearing ...UF scientists test improved gene therapy method for hereditary heart conditions
...heart tissue when glycogen accumulates in muscles, limiting their ability to contract. "This is a way of delivering gene therapy to the heart that is aimed at treating genetic diseases affecting the heart," Byrne said. "It's efficient and long lasting. One of the other distinguishing features of our researc......led the Calorie Restriction Society are devoted to limiting their caloric intake in hopes of improving their health and extending their lives. Society members, who call themselves CRONies (Calorie Restriction with Optimal Nutrition), have developed ways to eat low calorie/high nutrition diets. Fontana has d....... When plants are grown in small containers, the limiting factor is the oxygen that can reach the roots; thereby, a substrate much more porous than earth is needed. Normal soil encloses some 50% of air in its interior, while this substrate encloses 90% of air and 10% of solid material. This is why these sub...New method enables gene disruption in destructive fungal pathogen
...e generation of gene disruption mutants has been a limiting step for the analysis of gene function in most filamentous fungi. The new method takes advantage of a novel linear DNA construct that greatly improves the efficiency of targeted gene disruption. The DNA construct includes an antibiotic-resistance mar...A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases
...MS." IL-25 can be considered a "good" cytokine by limiting chronic inflammatory responses. At the same time, the ability of IL-25 to promote type 2 responses that drive asthma could be considered the "evil" side of the cytokine. By examining mice infected with Trichuris, a species of intestinal parasites k...St. Jude projects 90 percent cure rate for ALL
...our success in raising the cure rate for ALL while limiting toxic effects of therapy." That success is based to a large extent on the work done at St. Jude and elsewhere in identifying specific mutations in leukemic cells that strongly suggest the likelihood that treatment will fail the child, the authors re...Study: Competition for sex is a 'jungle out there'
...owards extinction. One reason that pollen becomes limiting to plants in regions of high diversity may be increased competition between the plants -- there are more plant species vying for the services of pollinators. Also, when there are a lot of species around, plants become more separated from other indiv...UC San Diego partners with Venter Institute to build marine microbial genomics cyberinfrastructure
...science at the Moore Foundation. "The major factor limiting its further progress has been the management of the very large quantities of data. We are delighted to be able to support the development of this community resource at one of the world's premier sites for high-speed networking and high-performance sc...Diverse tropical forests defy metabolic ecology models
... the metabolic ecology model to include light as a limiting resource that varies with tree size, the predictions could be improved. The necessary light data were available from only one site, and, in that case, observed growth and mortality patterns were consistent with predictions. Similarly, tree size distr...Ernst Mayr's theory illustrated in genetic epidemiology studies
...very common. Because rare factors tend to be the limiting factors in an interaction system, strong genetic effects are observed only at APOE ?the rare component ?and not at LDLR ?the common component. However, simply by altering the frequencies of the interacting genes, the apparent importance of these two...