Navigation Links

Tag: "ligand" at biology news

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in animal model

...ived neurotrophic factor (GDNF) or the GDNF family ligand (neurturin) into a genetically engineered herpes simplex virus (HSV). They then injected either of the recombinant viruses into the damaged cavernous nerve of rats. GDNF is an important nerve growth promoter and has been shown in other studies to con...

NIH researchers discover protein that appears to regulate bone mass loss, the cause of osteoporosis

...is week, confirms this unexpected connection. CD40 ligand appears to regulate cells that secrete chemicals that block bone metabolism, and the loss of this protein in people with X-linked Hyper IgM Syndrome appears to accelerate bone loss. The next step, say the researchers, is to determine whether experime...

Inflammation may play role in metastasis of prostate cancer

...f prostate cancer. The pathway is activated by a ligand that binds to a Receptor that Activates Nuclear factor Kappa-B (RANK). RANK ligand has been shown in previous studies to be an important inflammatory protein (cytokine) that can lead ...

Gene discovery may shed light on kidney disease

...in the Notch signaling pathway. JAG1 codes for the ligand Jagged1, a signaling protein that triggers receptors in the pathway. The NOTCH2 gene codes for Notch2, which is one of those receptors. The pathway as a whole is active during embryonic development, and transmits signals to cells to develop into spec...

Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection

...d tumor necrosis factor related apoptosis inducing ligand (TRAIL). "Each cytokine has unique functions. What we want to do is marry the function with the therapeutic response we want to achieve. Interleukin-23 promotes the function of dendritic cells and memory T-cells, important components in an immune re...

Worm hormone discovery may aid fight against parasitic disease

...gand, acts like a hormone, the first such hormonal ligand identified in C. elegans. Like a key fitting into a lock, the newfound ligand binds to a protein in the cell's nucleus called a nuclear receptor, a receptor designated DAF-12. On...

Study in Science holds promise for a new approach to drug therapy

...s interior. When a GPCR, for example, binds to its ligand on the outer surface of the cell, the receptor all...the biological message inside the cell sent by the ligand that activates a GPCR on the outside. The free G protein gamma-beta subunit can, for example, "turn ...

Renewed hope for Parkinson's patients

...igand," said Raulet. "It may also be that the Rae1 ligand helps trigger T cell responses that contribute to long term specific immunity. It's certainly an area of research that warrants more study." Other co-authors of the paper are Sandra Orsulic, assistant professor at the Massachusetts General Hospital ...

New study finds how cells with damaged DNA alert the immune system

...igand," said Raulet. "It may also be that the Rae1 ligand helps trigger T cell responses that contribute to long term specific immunity. It's certainly an area of research that warrants more study." Other co-authors of the paper are Sandra Orsulic, assistant professor at the Massachusetts General Hospital ...

Achilles heel of the herpes virus possibly found

...oncept. The findings suggest that B5 or its viral ligand could be a target for antiviral treatment, much like cell receptors for the entry of human immunodeficiency virus (HIV) into cells have become targets for new AIDS drugs. ...

Scientists solve structure of key protein in innate immune response

...of its rim, and the multiple grooves available for ligand binding. The researchers also discovered that mutations that interfere with LPS signaling cluster in a separate area near the pocket suggesting that the areas around the pocket are important in LPS transfer. Not only do these findings shed light on ...

Bound for destruction: Ubiquitination protects against improper Notch signaling

...membrane and which is capable ofinteracting with a ligand partner, such as the protein Delta, presentedon th...w Notchreceptors that have not been activated by a ligand are protected fromdigestion by that protease. Now, in a report published in the December29 issue of ...

1

Other Tags
(Date:9/16/2014)... the Exxon Valdez spilled 11 million gallons of oil ... up another giant oil spill in the Gulf of ... the Journal of Consumer Research , news coverage ... instead of catalyzing changes in the way fossil fuels ... media coverage of these two events helped to resolve ...
(Date:9/16/2014)... season of bounty. Fungi of dizzying variety erupt from ... search of elusive but delectable wild mushrooms. Part of ... hunt, and their mysterious not-quite-meat, not-quite-vegetable qualities that belie ... you are eating known to science? , The Fungi ... some estimates range up to 10 million species, only ...
(Date:9/15/2014)... INDIANAPOLIS -- Adding a common epilepsy drug to a ... fewer side effects. Moreover, the combination can reduce the ... to a team of pain researchers at Indiana University. ... patients with neuropathic pain, a difficult-to-treat condition often felt ... tissue damage. , "There is a huge unmet need ...
Breaking Biology News(10 mins):Exxon Valdez 2014: Does media coverage of manmade disasters contribute to consumer complacency? 2What's for dinner? Rapidly identifying undescribed species in a commercial fungi packet 2What's for dinner? Rapidly identifying undescribed species in a commercial fungi packet 3IU study: Combining epilepsy drug, morphine can result in less pain, lower opioid doses 2
(Date:9/17/2014)... (PRWEB) September 17, 2014 Angeldress.co.uk ... kinds of graceful special occasion outfits for worldwide clients. ... officials are thinking of opening the first flagship retail ... fashion industry. Recently, the company has unveiled its new ... promotion. , All its new products are offered ...
(Date:9/17/2014)... In a new video released for ... expert on the condition known as PPP, demonstrates a proven ... or PPP, is a condition that affects mostly uncircumcised men ... affected as well. The condition is characterized by small bumps ... is not a sexually transmitted disease and generally has no ...
(Date:9/17/2014)... Holon Solutions announced today that ... CollaborNet™ Health Information Exchange (HIE) solution ... between Coon Memorial Hospital, a 21-bed critical access ... community. , Coon Memorial is also using ... by physicians to the state’s Quitline tobacco cessation ...
(Date:9/17/2014)... Detroit, MI (PRWEB) September 17, 2014 ... are excited to be of the first in ... Ultherapy Décolletage Treatment, specifically designed to minimize the appearance ... Ultherapy, made waves in 2012 with the first FDA-cleared ... and face, and now they have expanded their brand ...
(Date:9/17/2014)... September 17, 2014 Lee Berman, a ... will be appearing on The Balancing Act® airing on ... episodes. , The segment will premiere on September 19 ... Balancing Act® airing on Lifetime Television®' with show host ... Funding Corp. for over a decade and is the ...
Breaking Medicine News(10 mins):Health News:Angeldress.co.uk Is Planning To Open Its First Retail Store And Offering Big Savings On Amazing Wedding Dresses 2Health News:New Video Depicts Best Treatment for PPP 2Health News:New Video Depicts Best Treatment for PPP 3Health News:Dallam-Hartley Counties Hospital District Deploys Holon's Health Information Exchange (HIE) Solution to Facilitate Improved Patient Care 2Health News:Dallam-Hartley Counties Hospital District Deploys Holon's Health Information Exchange (HIE) Solution to Facilitate Improved Patient Care 3Health News:FACE Skincare Medical Wellness Debuts Ultherapy Décolletage Treatment 2Health News:Lee Berman Will Appear On The Balancing Act® airing on Lifetime Television® 2
Other Contents