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Tag: "lifespan" at biology news

Agent slows aging in mice

...100 days. “If NDGA turns out to extend maximal lifespan by 20 or 30 percent, people would accept that as an important finding,” Miller says. No one excited by these early results in mice is advised to bulk up on creosote bush leaves as a way to defy old age. If NDGA pushes the aging envelope in the fin...

It's never too late to get it back! Aging interrupted

...hentic “anti-ageing drugs?capable of extending the lifespan of healthy people. The technique we have developed...ope is that these drugs will be able to extend the lifespan of healthy animals, and possibly, after further testing, healthy humans? says Professor Spindler who...

Researchers find link between food odors and lifespan in fruit flies

...es that restricted dietary intake can increase the lifespan of many species, but the mechanism that causes thi...on report that exposure to food odors can modulate lifespan and partially reverse the longevity-extending effects of dietary restriction in fruit flies. "Not...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

..., well-being and motor function was preserved, and lifespan was extended by >70%. The researchers d...th a smaller burden of material to metabolize. The lifespan of the mice doubled. (Neither treatment could work as effectively on its own. In fact, the effect wa...

Meat and two neutrons -- the key to a longer life

...icates that this approach can potentially increase lifespan without adverse side effects. If this is borne out...sed routinely. Previous successes in extending lifespan have involved withdrawing food to the point of near starvation, a process called caloric restriction...

1/3 of sexually active older adults with HIV/AIDs has unprotected sex

...2015 because medical intervention has extended the lifespan of those infected with HIV. Additionally, drugs such as Viagra have made it possible for older adults to remain sexually active longer. Past studies have shown that up to 65 percent of older adults ages 60 to 71 have sexual intercourse. Among old...

Stress hormones may play new role in speeding up cancer growth

...cer therapy, and therefore extending the patient's lifespan and improve their quality of life."...

Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese

...rchers have used a single compound to increase the lifespan of obese mice, and found that the drug reversed ne...nce 2003, resveratrol has been shown to extend the lifespan of worms and flies by nearly 30 percent, and fish by almost 60 percent. It has also been shown to p...

Studies find general mechanism of cellular aging

...s, which proliferate continuously during the adult lifespan and produce massive amounts of new blood cells on an hourly basis. Their results suggest that p16INK4a is the molecular basis for an old-age "signal" previously observed in blood stem cells. The Harvard study also showed that blood stem cells from ol...

Longer-lived rodents have lower levels of thyroid hormone

...tration differences correlate with maximum species lifespan and suggest an important regulatory role of thyroid hormone in longevity," the researchers concluded. However, because T3, levels did not differ significantly among all the groups, further research in this area using larger sample sizes (numbers of r...

Temperament linked to onset of cancer and early death in female rats

...y, University of Chicago researchers looked at the lifespan of male rats and found that the adventuresome males lived longer. Because the male rats died of a variety of diseases, they could not establish a reason for the differences. The new study links personality specifically with cancer. ...

Buildup of damaged DNA in cells drives aging

...d, according to the authors. The first is that our lifespan and how well we age is determined by the genes inherited from our parents. The second is that lifespan and fitness in old age is determined by how much damage we incur over our lifetime. "Our study s...

Worm links cancer risk to ageing

...ls don't divide if they are damaged also determine lifespan in the nematode worm," explained Professor Gordon Lithgow, who carried out the work at The University of Manchester. "Our research has shown that these 'checkpoint proteins' ?thought only to operate in cells that divide ?function in cells that no lo...

Cutting calories slightly can reduce aging damage

...ttle less food and exercising a little more over a lifespan can reduce or even reverse aging-related cell and ...asing the animals' activity extended their average lifespan and significantly overturned the negative effects of cellular aging on liver function and overall he...

Evolutionary forces explain why women live longer than men

...in almost every country, and the sex difference in lifespan has been recognized since at least the mid-18th century," said Daniel J. Kruger, a research scientist in the U-M School of Public Health and the Institute for Social Research. "It isn't a recent trend; it originates from our deep evolutionary history...

Diabetes research takes wing thanks to long-lived fruit fly

... calories an organism ingests ?generally increases lifespan in organisms ranging from worms to flies, and maybe humans. Somehow, JNK and the insulin receptor together seem to work in tandem to affect life span. "We're learning that an organism's life span may not be limited by design," said Bohmann. "It was ...

Large dinosaurs were extremely hot in their day, UF study finds

... 300 percent change in rates of population growth, lifespan and population density." For many years, scientists had assumed that dinosaurs were cold-blooded, or ectotherms, with a slow metabolism that required the sun's heat to regulate temperature. But in the late 1960s, the notion emerged that dinosaurs, ...

Matrilin-3 gene discovered to prevent onset of osteoarthritis

...n-3 was removed, the mice had a normal and fertile lifespan and appeared to have normal skeletal development. However, without matrilin-3, researchers noticed that during embryonic development, mice developed premature and extended hypertrophy ?the phase when cells increase in size to form bone. Later in l...

Thinner and younger

...nsistent caloric restriction increased the maximum lifespan in mice and rats by about 30 percent and protected...es sense that losing weight might increase average lifespan by lowering the risks of some age-related diseases, such as diabetes and atherosclerosis. But in ani...

Chocolate milk could be key to longer, healthier life

...e athletes out of the elderly, but to increase our lifespan and quality of life in old age. "The ability of people to create energy and perform work stems from structures that exist inside our cells called mitochondria. As we grow older the amount of mitochondria we have decreases and with it our respiratory...

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