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Tag: "levels" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...rectly into the circulation. In turn, these rising levels of LH and FSH cause the testes and ovaries to prod...ted by GnRH secretion, was no longer dormant, with levels 25-times higher than its baseline of zero. In addition to Dr. Plant, other authors of the PNAS pape...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...d fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one... "turn down" the mechanism, decreasing cholesterol levels and heart disease risk, explained Spiegelman, who is also a professor of cell biology at Harvard Med...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...of tumors as mice with the mutation but whose IGF2 levels were normal. The tumors grew at the same rate in both sets of mice, suggesting that more tumors get started in the mice with extra IGF2, notes Feinberg. "In the mice, loss of imprinting of IGF2 roughly doubles the risk that the genetic mutation will...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

..., the low-birth-weight babies began showing higher levels of blood glucose. "By 6 months, these levels had spiked abnormally, to 500 mg/dl -- the equivalent of serious, full-blown diabetes in humans," Dr...

Controversial drug shown to act on brain protein to cut alcohol use

...n ordirectly into the same brain region where GDNF levels were shown toincrease.The research also showed that Ibogaine was quite effective inpreventing relapse, or "falling off the wagon" -- the vulnerability ofrecovered alcoholics or addicts to return to uncontrolled drinking ordrug use when exposed to the...

Neuronal 'traffic jam' marks early Alzheimer's disease

...ey observed in the mice and humans by reducing the levels of a key transport protein, kinesin-1, the cell's principal molecular motor for transporting proteins. "We made a modest reduction in the level of a motor protein called kinesin-1 in the mice, and we got a considerable increase in plaque production a...

Anti-bacterial additive widespread in U.S. waterways

...the researchers comparedtheir predicted nationwide levels of contamination to experimentallymeasured concentrations in the Greater Baltimore region, and found nostatistically significant differences. The results also show that thelevels of triclocarban in water resources nationwide are much higherthan previ...

Scientists Replicate Hepatitis C Virus in Laboratory

...lture. Electron microscopy showed evidence of high levels of viral particles resembling fully-formed HCV outside of the human liver cells in the culture medium. The researchers believe that the HCV construct contained within the human liver cells behaved like a true HCV infection by producing fully formed c...

Novel antiviral technology inhibits RSV infection in mice

...ter infection with RSV, showed significantly lower levels ofvirus in the lung and less airway inflammation and hyper-reactivitythan untreated mice....

Inflammatory molecules released by pollen trigger allergies

...y allergies are more prevalent in places with high levels of car exhaust emissions. Traidl-Hoffmann and colleagues showed that extracts from birch pollen and other common allergens block the production of a soluble protein by immune cells that normally inhibits allergic reactions. They went on to identify ...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...a geneticfingerprint of what patients with varying levels of iron deprivationlook like."A patient's blood could easily be tested for specific diagnosticmarkers that would indicate his level of iron deprivation, he said.With diagnostic markers in place, physicians could translate theseverity of the disease i...

Live Recombinant Adenovirus Vaccine Technique Explored

...expression machinery. L1 is expressed at very high levels in some recombinants. Dr. Ketner believes that the replicating live recombinant adenovirus model shows promise as a means of developing economical and long-lasting vaccines for many illnesses. Ongoing research is aimed at determining the effectivene...

The secret lives of whales

...nd analyzing their contaminant loads, he could map levels of pollutants in different ocean. “The oceans act as a conveyer belt carrying contaminants across the globe and depositing them in the fats of seafood,?says Payne. Now in the final year of a five-year global voyage, Payne’s institute has found and co...

Dinosaur DNA? New Patent Covers Degraded DNA recovery

... is substantially representative -- at microscopic levels -- of the species from which the degraded sample was obtained. Dr. Ensley and his team hope to apply this new technology to products they will make available later this year. "We don't plan to turn house cats into saber tooth cats or create a Jurass...

Gene therapy converts dead bone graft to new, living tissue

...ounding inflammatory tissue for differences in the levels of the active genes. He discovered that the genes ... needs the calcium, and rebuilding it when calcium levels rise. The bone that is rebuilt is now fully the patient's own, as if the dead bone were a house bein...

Researchers reveal the infectious impact of salmon farms on wild salmon

...d juvenile salmon was 73 times higher than ambient levels near the farm and exceeded ambient levels for 30 kilometers of the wild migration route." This increase in sea lice abundance is likely to be...

Jefferson Virologists Coax HIV Out of Hiding

...who had been taking HAART and who had undetectable levels ofvirus. Using a special technique, they screened ...?They found that the virus wasstimulated to higher levels and was activated in more patients thanwith other compounds. Dr. Pomerantz’s group also discovered t...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

... if any, the chemicals had. They also measured the levels ofproteins in the normal and treated embryos to check the visual data. Read the full paper ...

Study identifies predictors of HIV drug resistance in patients beginning triple therapy

... if any, the chemicals had. They also measured the levels ofproteins in the normal and treated embryos to check the visual data. Read the full paper ...

Enzyme allows B cells to resist death, leading to leukemia

...ersity School of Medicine nowdemonstrate that high levels of expression and altered cellularlocation of an e...ion, the enzyme was constantlyactive compared with levels of activity in normal donor cells.The authors went on to show that inhibition of Lyn was able to res...

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