leukemia 2 2

Tag: "leukemia" at biology news

Long-term cancer risk follows stem cell transplant recipients

...py for specific life-threatening diseases, such as leukemia or myelodysplastic syndrome, for which blood cell lineages (which originate principally in the bone marrow and circulate in the blood) are abnormal. Destroying the patient's own unhealthy stem cells in the bone marrow and replacing them with a compat...

Killing brain tumors from within: A 'Trojan horse' approach

... has already led to successful therapy in treating leukemia and some lung cancer patients....

Jumping gene could provide non-viral alternative for gene therapy

...irus and three children in another study developed leukemia because the virus inserted itself upstream of a cancer-causing gene. "With viruses, you don't have control," says Dr. Kaminski. "People have tried to modify viruses for site-specific integration and have not been very successful. Once they get into...

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

...r, and to suggest new therapies for drug-resistant leukemia and advanced prostate cancer. Scott Armstrong, M...ome therapy-resistant cases of acute lymphoblastic leukemia (ALL) in children. So-called "glucocorticoid" drugs like prednisone are very effective in many cases...

Loosen up, DNA: Leukemia gene changes genetic packaging

A signaling system involved in many forms of leukemia and lymphoma is more powerful than scientists have...uch more likely to get any one of several types of leukemia or lymphoma. To learn more about how JAK/STAT works, a team led by Willis Li, Ph.D., assistant pr...

New strategy rapidly identifies cancer targets

...oteins ?instead of the genes ?inside acute myeloid leukemia (AML) cells, the researchers have dramatically red...." To find these markers, the team took myeloid leukemia cells and chemically digested them into a mixture of protein snippets called peptides. Next, they ex...

Can you hear me now? Scientists find previously unknown receptors on adult stem cells

...imental in certaincircumstances -- for example, in leukemia patients that are vulnerable toinfections after re...infection. Scientists need tostudy stem cells and leukemia cells in these diseases to determine if theyare using this messaging system," said Kincade. Another...

Mouse mimics chronic leukemia, will aid drug development

...real animal model for an incurable form of chronic leukemia and should greatly aid the development of new drug...malignancy that closely mimics chronic lymphocytic leukemia (CLL). The lack of an animal model has greatly hampered the development of new treatments for CLL as...

Mass. General study finds potential ovarian cancer stem cells

...ncer stem cells have been previously identified in leukemia and breast cancer and in cell lines of central nervous system and gastrointestinal tumors. Standard treatment for ovarian cancer ?surgical removal of all involved tissues followed by chemotherapy ?usually appears successful, but treatment-resista...

New human retrovirus originated in mice

...sely resembled that of a mouse virus called murine leukemia virus (MuLV). Murine leukemia virus is known as an endogenous virus because it normally exists as an integrated part of the mouse ...

Cancer virus protein needed for successful infection

...t 5 percent of those infected develop adult T cell leukemia or lymphoma (ATLL), an aggressive disease characterized by a long latent period and the proliferation of T lymphocytes. The virus is spread by sexual activity, infected blood and breast milk. For this study, Lairmore and a group of collaborators de...

Mutation in blood stem cells provides clues to cancer development

...o many red blood cells and which can lead to acute leukemia ?have a mutation expressed in the stem cell, the p...ovides more insight into why some patients develop leukemia or other malignancies, while others don't, by identifying determinant cancer genes and the signaling...

Retinol for combating leukemia cells

...lysed the effect of retinamide in certain types of leukemia - lymphoblastic leukemias. Nowadays, samples from ... in Bilbao are used in order to get these types of leukemia cells. Lymphoblastic leukemias are, as their name indicates, a type of leukemia that affects lympho...

St. Jude projects 90 percent cure rate for ALL

...ersally fatal childhood cancer acute lymphoblastic leukemia (ALL) could reach 90 percent in the near future, thanks to improvements in diagnosis and treatment over the past four decades, according to investigators at St. Jude Children's Research Hospital. Almost 4,000 cases of ALL are diagnosed in the United ...

When good DNA goes bad

...enetic instability associated with cancers such as leukemia and lymphoma, according to a study by researchers at The University of Texas M. D. Anderson Cancer Center. The study, issued in advance of the Feb. 21 edition of the Proceedings of the National Academy of Sciences, demonstrates for the first time t...

Single microRNA causes cancer in transgenic mouse

... new insight into the development of some forms of leukemia and lymphoma and at the same time underscores the ... that miR155 was unusually active in some types of leukemia and lymphoma, and that its presence indicated a poorer prognosis in patients with breast and lung ca...

MiRNA fingerprint identified in platelet formation

...lopment, but turned on in certain platelet-related leukemia cells," says lead author Dr. Ramiro Garzon, a clin...t, especially in diseases like chronic lymphocytic leukemia and lymphoma. Relatively little was known, however, about miRNA functionality in platelet formation....

Viral protein helps infected T cells stick to uninfected cells

...t 5 percent of those infected develop adult T cell leukemia or lymphoma (ATLL), an aggressive disease characterized by a long latent period and the proliferation of T cells. The infected cells are spread from person to person during sexual activity and by blood and breast milk. In the body, the HTLV-1 mainl...

Mouse study reveals human X-SCID gene therapy poses substantial cancer risk

...onths of age. In the human gene therapy trials, leukemia did not appear until 2-3 years after treatment, Woods says. "This indicates that preclinical experimental treatments involving transgenes should include long-term follow-up before entering a clinical trial," says Woods. But, more fundamentally, the...

Performing monkeys in Asia carry viruses that could jump species to humans

...ersion of the virus, HTLV, a known cause of T-cell leukemia in people. One macaque tested positive for herpes B virus, also known as CHV-1, which rarely infects humans, but, in the 40 known human cases, was associated with an 80 percent fatality rate. The researchers still do not know the prevalence of such...

1 2 3 4