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New push for public health, AIDS spending at African Union summit

...e 52 countries included in the African Union spend less than 10 per cent of their annual revenues on health, anti-AIDS and anti-HIV efforts included. Controversial drug trials, battles over patents and the fate of millions of orphans are also likely to be discussed at a summit session devoted to the figh...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

...umans, can only repair these lesionsthrough a much less direct and elaborate process called nucleotideexcision repair.In the new work, Dr. Bert van der Horst and colleagues studied theeffects of CPD and 6-4PP lesions by providing mice with transgenesencoding CPD and 6-4PP photolyase enzymes.Although mice ...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

... effect. At birth, their babies weighed 23 percent less than the control group. After delivery, all babies nursed and all mothers ate a full diet. "By the time the babies were weaned, at three weeks, the low-birth-weight group had caught up with the others, something we see in human babies too," said Dr....

Tiny particles could solve billion-dollar problem

...sts or microorganisms that break the TCE down into less toxic or non-toxic constituents. In general, chemi...her chemicals. For example, in the bulk palladium, less than 4 percent of the palladium atoms were on surface of the particle. Pure palladium nanoparticles ...

UW's Rosetta software to unlock secrets of many human proteins

...dthe world, he said, the task will be completed in less than a year.IBM's World Community Grid, which was built using grid technologydeveloped by United Devices, will enable millions of people tovolunteer their personal computers to run Rosetta during periods ofcomputer downtime.The information will be en...

Researchers find how protein allows insects to detect and respond to pheromones

...dthe world, he said, the task will be completed in less than a year.IBM's World Community Grid, which was built using grid technologydeveloped by United Devices, will enable millions of people tovolunteer their personal computers to run Rosetta during periods ofcomputer downtime.The information will be en...

Novel antiviral technology inhibits RSV infection in mice

...significantly lower levels ofvirus in the lung and less airway inflammation and hyper-reactivitythan untreated mice....

Inexpensive, mass-produced genes core of synthetic biology advances at UH

...uld allow for development and production of safer, less toxicproteins that are currently used in disease treatment. It also couldallow for production of large molecules that do not occur naturally,but that are needed for new generations of vaccines and therapeuticagents, including vaccines for HIV and oth...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

...these unexpected side effects are very low -- much less than 1 percent." Co-investigator Michael Ackerman, M.D., Ph.D. agrees that the benefits of the drugs far outweigh the risks. "Our findings should not jeopardize the availability of protease inhibitors because these drugs are too important for the su...

Mitochondrial DNA mutations play significant role in prostate cancer

...cancer samples had mutationsin the COI gene, while less than 2 percent of the samples from patientsfound to be cancer free harbored mutations in this gene. In a controlsample of 1,019 individuals from the general population, 7.8 percenthad mutations in the COI gene. The researchers found both germ-line(in...

Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey

...ons that are resistant to antibiotics, making them less severe.Based on an understanding of how this toxin system works, we hope todevelop toxin inhibitors,?says Gilmore.The third area of interest is currently science fiction, says Gilmore.“If bacteria can see cells in the environment, maybe we can tame t...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

... cell cultures. “We measured more than 90 percent less histamine in the cultures with GFD,?says Dr. Saxon. “Those results suggested that GFD successfully prevented the immune cells from reacting to cat allergen. The next step was to test GFD in mice that we had made allergic to the allergenic protein fou...

Yale Scientists Find MicroRNA Regulates Ras Cancer Gene

..." Lung cancer currently has a poor prognosis with less than 15 percent of patients surviving five years. The lungs, however, are relatively accessible for inhalation of potential gene therapy agents. "While this is not likely to cure the cancer," said Slack, "after diagnosis, gene therapy with let-7 may ...

New Clues Add 40,000 Years to Age of Human Species

... Forty years ago, radiometric dating methods were less accurate and suggested an age of roughly 130,000 years. No one was able to securely tie both sets of fossils to the same time period. "Fortunately, small pumice fragments from two sediment layers were perfect for precise isotopic dating," says McD...

Poplar trees redirect resources in response to simulated attack

...at kill off the attackers or make their own leaves less tasty," said Benjamin Babst, a Ph.D. student in the biology department at Tufts University and lead author on that paper. "But there's a suspicion that plants also respond by building up tolerance, for example by putting aside more carbon into storag...

Purdue proves concept of using nano-materials for drug discovery

.... The goal is to produce "laboratories-on-a-chip" less than a half-inch square that might contain up to a...erapy drugs from tumor cells, making the treatment less effective. Cancer cells exposed to chemotherapy drugs produce a disproportionately large number of t...

Scientists rid stem cell culture of key animal cells

...ct of changing stem cell growth conditions - using less feeder cell material, or no serum replacement, for instance. Unexpectedly, Xu found that the presence of serum replacement promoted stem cell differentiation. Digging deeper, he found that serum replacement mimics the activity of bone morphogenetic ...

Essential mangrove forest threatened by cryptic ecological degradation

...st aesthetic species is masked by the expansion of less important species. The authors emphasize that such cryptic ecological degradation must be acknowledged by policy and decision makers if mangrove protection is an aim. The research team argues that early detection of such changes should be adopted and...

Experiments provide proof of how traveling in groups protects insects

...ect. By gluing radio transmitters -- each weighing less than half a gram -- to the backs of Mormon crickets in northeastern Utah and northwestern Colorado, Drs. Gregory A. Sword, Patrick D. Lorch and Darryl T. Gwynne showed experimentally that band formation indeed boosted insect survival. Sword is a res...

Experiments provide proof of how traveling in groups protects insects

...ect. By gluing radio transmitters -- each weighing less than half a gram -- to the backs of Mormon crickets in northeastern Utah and northwestern Colorado, Drs. Gregory A. Sword, Patrick D. Lorch and Darryl T. Gwynne showed experimentally that band formation indeed boosted insect survival. Sword is a res...

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