Severe mental retardation gene mutation identified
...cted genetic samples from 250 families in which at least two boys have mental retardation to help identify novel genes that cause X-linked mental retardation. The investigators systematically analyzed the X chromosome for gene mutations. Dr. Raymond says that the families are receiving information fro...New research may overturn conventional wisdom on drug-resistant tuberculosis
...ial sample was drug-susceptible or resistant to at least one drug and the subsequent sample resistant to one or more drugs. Of these patients, 84 percent (27 patients) had before-and-during samples with different genetic patterns and only 16 percent (5 patients) had identical patterns. Thus, there were mor...... Z chromosome are not fully dosage-compensated, at least at the transcriptional level. The study challenges current thinking about the role and mechanisms of dosage compensation in species with heteromorphic sex chromosomes. "Unlike mammals, birds have an ineffective dosage compensation," says Arnold. "...NIH announces phase III clinical trial of creatine for Parkinson's disease
...ovements, and stiffness of muscles. It affects at least one million people in the United States. Although certain drugs, such as levodopa, can reduce the symptoms of PD, there are no proven treatments that can slow the progressive deterioration in function. Creatine is marketed as a nutritional supple...Using dental X-rays to detect osteoporosis
...with over a third of adult women falling victim at least once in their lifetime. Wide-scale screening for the disease is not currently viable, largely due to the cost and scarcity of specialist equipment and staff. The team has therefore developed an innovative software-based approach to detecting osteop...Tiny clue reveals new path toward heart disease
...ic blueprint -- of a group of families in which at least two siblings had early onset coronary artery disease, looking for regions of "linkage" where DNA variations appeared to be inherited along with the disease. They found just such a region: a small section of the long arm of chromosome 3 where just a h...Recently discovered species gain protection
...at they are still awaiting formal descriptions. At least one of these species is believed to be found only at this site, known as La Forzosa, and belongs to one of the most globally threatened amphibian groups, the harlequin toads. In addition to the piha, the reserve also contains populations of many ot...'Ancestral eve' was mother of all tooth decay
...igration of a small group of Asians who founded at least one group of modern-day Caucasians." Additional branches, tracing the coevolution of humans and bacteria from Asia into North and South America, will be drawn in the next phase of Caufield’s analysis. ...Chimpanzees found to use tools to hunt mammalian prey
...hers have discovered evidence that chimpanzees, at least under some conditions, are capable of habitually fashioning and using tools to hunt mammalian prey. The work, reported by Jill Pruetz of Iowa State University and Paco Bertolani of the University of Cambridge, will appear online in the journal Curren...Anti-herpes treatment reduces HIV levels in women infected with both viruses
...the blood of HIV-1 infected patients increases, at least temporarily, during episodes of HSV reactivation. Lead author Dr. Nicolas Nagot, of the London School of Hygiene & Tropical Medicine (LSHTM), explains: 'Behavioural interventions are not always successful, as knowledge does not necessarily tran...Lower carbon dioxide emissions from coal-fueled power plants possible with technology development
...process for capturing carbon dioxide so it uses at least 10 percent less energy. “The work we’re doing at The University of Texas at Austin will provide the technical understanding for companies to use this technology in prototype and commercial scale plants,?said Rochelle. “With the current mix of...Scripps Research study reveals new activation mechanism for pain sensing channel
...es. Apparently, reactive compounds can activate at least two pathways through cysteine modification as a warning against cell damage, the study concluded. "Our findings, which are the result of a successful collaboration with the Ben Cravatt and Peter Schultz labs at Scripps Research, show that modific...Birds found to plan for the future
...nsidered an exclusively human activity, but now at least one species of bird has also been found to plan for tomorrow. The finding also raises the intriguing possibility that, like humans, birds may get anxious about the future. Research published today (22 February) in the journal Nature shows that wester...Ladybugs may be cute, but watch out when they get near wine
...ce with a less pronounced jaw and smaller teeth at least 300,000 years later than commonly believed, perhap...Australopithecus and early Paranthropus, living at least three million and 2.5 million years ago, respectively. Dr. Bromage developed his reconstruction...Man's earliest direct ancestors looked more apelike than previously believed
...ce with a less pronounced jaw and smaller teeth at least 300,000 years later than commonly believed, perhap...Australopithecus and early Paranthropus, living at least three million and 2.5 million years ago, respectively. Dr. Bromage developed his reconstruction...CSHL research ties harmless viruses to cancer
...his CSHL colleague Dominik Duelli estimate that at least 18 of 29 virus families that infect human cells have species that fuse cells, which implies that CIN and cancer might be caused by viruses, even those that are considered harmless. ...Hay fever can send work productivity down the drain
...der that 20 to 50 million Americans suffer from at least some symptoms related to hay fever, or allergic rhinitis, said Sheryl Szeinbach, the study's lead author and a professor of pharmacy practice and administration at Ohio State University. “That means the potential loss of millions of hours of work ...E. coli bacteria migrating between humans, chimps in Ugandan park
...cent of the chimps studied were found to harbor at least one E. coli isolate that was clinically resistant to an antibiotic. Antibiotics are used frequently in human populations in this region of Uganda, Goldberg said, but antibiotics have never been used in local wildlife, so the antibiotic-resistant bact...New culture method for hepatitis C virus uses primary hepatocytes and patient serum
...plication and production of virus particles for at least 2 months, with these virus particles able to infect new cells. In their first experiments, Fausto and colleagues transfected hepatocyte cultures with HCV genomic RNA and found replication of HCV RNA genomes and production of core protein (for vir......As are not encoded in the DNA, which means that at least two versions can being produced by one gene. This ... likely to be correct," Nishikura says. "And in at least the case of the one gene we investigated, this differential has physiological consequences seen in t...