Researchers discover key mechanism by which lethal viruses Ebola and Marburg cause disease
...is speculated that filovirus infections account at least in part for the recent decline in the gorilla and chimpanzee population in central Africa. There is no cure or approved vaccine for either Marburg or Ebola virus. Immunosuppression occurs early after infection and allows the viruses to reproduce ra...Scientists get best look ever at water-life connection
...r molecule to connect with the protein required at least 100 picoseconds to complete. So when it comes to supporting life -- on the molecular scale, anyway -- water has to move 100 times slower to get the job done. "The fast-moving water has to slow down to connect with a slow-moving protein -- it's that...Holiday gluttony can spell disaster for undiagnosed diabetics
...and eating right. Exercise regularly. Walk at least 30 minutes a day. Eat a nutritious diet high in fiber and whole grain. Reduce the intake of high-calorie food. "Various research studies have shown that maintaining a healthy lifestyle with a balanced diet, weight management and regular exer...First-time analysis reveals millions of Europeans left at risk from influenza
..., the World Health Assembly resolved to aim for at least 50% of the elderly population to receive annual seasonal vaccines by 2006, and 75% by 2010. In October 2006, the WHO followed this with a call to all countries preparing for a pandemic to increase use of seasonal influenza vaccines 2 to help increase...Researchers barcode DNA of Venice museum's vast fungi collection
...e do not know of any similar project in Europe, at least of this dimension," said Enrico Ratti, the museum's scientific director. "The importance of this project is in the cooperation between different subjects, namely private collectors, a private association, a public municipal museum and a foreign un...Genomic comparison of lactic acid bacteria published
...tic Acid Bacteria Genome Consortium, a group of at least a dozen academic organizations formed in 2001. Paul Richardson, DOE JGI Genomic Technologies Program head, said that the functional classification embraced a variety of industrially important genera, including Lactococcus, Enterococcus, Oenococcus, P...Cellular traffic backups implicated in skeletal malformations
...'s fascinating that the gene we have found was the least expected." It turns out that the zebrafish mutant has a human counterpart, making the crusher mutant the first animal model that links ER to Golgi protein transport to a human craniofacial birth defect. In the same issue of Nature Genetics ?and...Extraordinary life found around deep-sea gas seeps
...and is one of the few places in the world where at least four types of chemosynthetic habitats occur in close proximity, allowing scientists to address key questions about the patterns of biological distribution that cannot be addressed elsewhere. The team visited eight cold seep sites on the continental...Two-faced protein can stop metastasis or promote it, researchers say
... "We show that E-cadherin suppresses invasion, at least in part, by binding to p120 protein in the cell," Anastasiadis says. "If E-cadherin is missing, p120 is free to bind to mesenchymal cadherins, setting off a process that leads to metastasis." Thus, p120 acts as a "rheostat" that promotes either stab...PNAS study reveals why organs fail following massive trauma
...st profound effect on just 338 of the genes, an at least two-fold change in their expression, the process by which the information they store is converted into proteins that carry out bodily functions. Post-traumatic genetic changes had two major effects on T cells: a marked increase in regulatory protein ...Biofuel cells without the bio cells
... just a few seconds," Squier said, "but flux is at least as good as what you would find in the most efficient bioreactors, which rely on living bacteria." Biological fuel cells, or biofuel cells, are not yet powerful enough to be commercially viable but they offer the promise of breaking down sewage and ...Pesticides need sunscreen to beat the heat
...t the pesticides can be exposed to sunlight for at least twice as long without degrading. Dr Wen, of the Bejing University of Chemical Technology, believes that the pesticide will be more effective as a result, thereby reducing the amount required and the cost to the farmer. It could also mean cleaner w...Proteins anchor memories in our brain
...so train our focus on the thymus, where we know at least some of the autoimmune disease is triggered, we may be able to determine just what self-antigens are important and shut down the autoimmune process targeting those self -antigens." The team is collaborating with Jeffrey Bluestone, PhD, director of ...Autoimmune disease triggered if T cells miss a single protein early on
...so train our focus on the thymus, where we know at least some of the autoimmune disease is triggered, we may be able to determine just what self-antigens are important and shut down the autoimmune process targeting those self -antigens." The team is collaborating with Jeffrey Bluestone, PhD, director of ...Study: Living coral reefs provide better protection from tsunami waves
...demonstrates that healthy reefs offer the coast at least twice as much protection as dead reefs. The finding provides the first quantitative confirmation of a widely held theory regarding the value of living coral reefs as a defense against tsunami waves, which are often generated by powerful undersea eart...Otherworldly bacteria discovered two miles down
...sea volcanoes. Yet these communities all depend at least in part on nutrients that can be traced back to photosynthetic plants or bacteria. The international team led by T. C. Onstott of Princeton University,* which also includes Carnegie staff scientist Douglas Rumble and former Carnegie postdoctoral ...Too mellow for our predatory world
...the Galápagos Islands live without predators - at least this was the case up until 150 years ago. Since then they have been confronted with cats and dogs on some islands of the Archipelago. For scientists, they are therefore a suitable model of study in order to discover if such generally tame animals are...Changing length of days reverses how estrogen affects aggressiveness in mice
...ay can affect how estrogen is used in the body, at least in some species, how are other environmental factors such as diet affecting estrogen in humans? It is something we don't know enough about." ...China's environmental challenges
...t of sewage generated will go up by a factor of at least 1.3, putting the country's already fragile freshwater systems under greater strain. The authors wonder: will China "?.continue down the same road as in the past two decades, or will environmental quality, energy efficiency, and the conservation of r...Very low birth weight linked to reduced quality of life in pre-school children
...re children who attended preschools and weighed at least 2500g (five pounds and eight ounces) or more at birth. The mothers of very low birth-weight babies tended to be younger than the mothers in the control group, and were half as likely to be educated to college degree or higher. 45 per cent didn't w...