Are one-third of costly implanted heart devices unnecessary? New study suggests yes
...oup of patients who were eligible for ICD therapy, leading to estimates that 50,000 new patients each year can qualify for the devices based on criteria relating to their heart rhythm and pumping capability. But if every Medicare participant who qualified for an ICD under current guidelines received one, it ...Bisexual fruit flies show new role for neurochemical
... The gene mutation also made the flies bisexual, leading him to name the gene "genderblind." "The mutants are completely bisexual, but fertile. It's the first gene that really specifically affects homosexual behavior without affecting heterosexual behavior," he said. "Trying to understand fly bisexuali...Rapid oral HIV test shows great promise according to MUHC-led research
...e Control (CDC) called for more definitive studies leading to this study in rural India. "Based on our findings, the oral test is the preferred choice for HIV field testing by rural Indians," says Dr. Pai, a physician epidemiologist supported by the Canadian HIV Trials Network. "The other advantages are t...Cold sore virus might play role in Alzheimer's disease
...e known as ApoE-4, which after advanced age is the leading known risk factor for getting Alzheimer's disease, with the form of herpes ?herpes simplex 1 or HSV ?that infects more than 80 percent of Americans and causes cold sores around the mouth. The findings from a group at the University of Rochester Medic...Robotic therapy helps restore hand use after stroke
...icans suffer strokes annually. Stroke is the third leading cause of death in the country. And stroke causes more serious long-term disabilities than any other disease. Nearly three-quarters of all strokes occur in people over the age of 65 and the risk of having a stroke more than doubles each decade after t...New mechanism for nutrient uptake discovered
...and are looking at this possibility further. A leading expert in transporters, Professor Dale Sanders, head of the biology department at the University of York in the U.K. commenting on the work said: "Loqué, Frommer and co-workers have demonstrated very beautifully how plant ammonium transporters are c...Trusting your instincts leads you to the right answer
...gher-level and lower-level cognitive processes are leading us to the same conclusions, there is no issue. Often though, our instincts and higher-level functions are in conflict and in this case our instincts are often silenced by our reasoning conscious mind. Participants would have improved their performanc...Are we killing the world's oceans?
...? Members of the news media are invited to join leading international researchers and government decision-...m the Sea?" on Feb. 21 Pauly is one of the world's leading fisheries conservation scientists, and a vocal and influential critic of current fishing practices. ...Antibody therapy prevents type 1 diabetes in mice
...chronically elevated levels of sugar in the blood, leading to blindness, kidney failure, heart disease and nerve damage. Previously known as juvenile diabetes, type 1 diabetes is usually diagnosed at a very early age, but in some cases it can be diagnosed in adulthood. In this study, the Pitt researchers t...Research on grey mould offers possible breakthrough in tomato cultivation
...mato varieties can be resistant to grey mould. The leading company De Ruiter Seeds is already applying these methods in its breeding programme. Finkers started off with wild tomato accessions that were resistant to grey mould. When crossing the resistant wild tomato Solanum habrochaites LYC4 with the suscep...Saving endangered whales at no cost
...uals remains on the east coast of North America. A leading threat to the species is lethal entanglement by fishing gear: Photographic evidence indicates that 75% of individuals show signs of entanglement, mostly from lobster fishing gear. In the new work, the researchers analyzed the costs and benefits o...Biologists develop large gene dataset for rice plant
... maize and wheat." Research on small RNAs "is a leading edge in plant biotechnology," said Machi Dilworth, Director of the National Science Foundation (NSF)'s Division of Biological Infrastructure, which along with the U.S. Department of Agriculture, funded the research. "This work will contribute to an u...ESA launches new project to protect biodiversity
...calisation Satellites ?has been chosen to take the leading role in the technical development of the services and products. "DIVERSITY responds directly to key concerns expressed through the Convention process regarding the future integrity of natural ecosystems, the survival of species and the goods and s...Researchers discover gene crucial for nerve cell insulation
... disrupts the functioning of the normal EGR2 gene, leading to a disorder of the nervous system. In many genetic conditions, the unaffected copy of an affected gene continues to produce its protein. However, the researchers found that the mutant EGR2 copy interferes with the interaction between the normal...UW launches study testing adult stem cells for heart damage repair
...s the most common form of heart disease and is the leading cause of death in the United States. This conditio...ses, the heart muscle can be irreversibly damaged, leading to significant disability, progressive heart failure and often death. ...Scientists find new genes for Crohn's disease
...diseases (IBDs). More importantly, those genes are leading us to the biological pathways that relate to IBD pathogenesis. By understanding these pathways, we may be better able to develop more effective therapies for IBD," said consortium member Richard H. Duerr, M.D., associate professor of medicine and hum...Putting an old drug to a new use
...l as iron promotes the formation of toxic radicals leading to tissue damage. Iron overload is the consequence of one of the most common genetic disorders in Europe, hereditary hemochromatosis, which affects about one in 300 Europeans. Excess iron also accumulates after repeated blood transfusions and can cau...Researcher to study astronaut bone loss for space biology agency
...is a steep drop in the creation of new bone cells, leading to bone loss. To investigate the hypothesis, Long will take a two-pronged research approach. In the first part, he will study a model of skeletal loading and unloading in human bone cell culture. In the second part, skeletally unloaded rats will b...Scientists find potential 'off-switch' for HIV virus
...tivate the Tat resistor to interrupt the reactions leading to viral infection could one day have repercussions in both the lab and the clinic." Weinberger and Shenk share their findings in a research paper appearing in the Dec. 26 issue of the online journal Public Library of Science Biology. "We have...Gene that makes people 'early to bed and early to rise' demystified
...cle, fall below the threshold earlier than normal, leading to activation of transcription earlier and resulting in a shorter period." The advance in understanding of PER2's role may ultimately lead to methods for people, such as nurses who must care for patients in the middle of the night, to synchronize t...