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Tag: "latent" at biology news

Experimental TB drug effective against resistant and latent mycobacterium tuberculosis

... but could also be the first compound to treat the latent stage of infection as well. Researchers report th...all forms of tuberculosis, even drug-resistant and latent infections," says Albert Owens, President of FASgen, Inc., the company working to bring the drug to ...

Depression model leaves mice with molecular scar

...ilencer molecules, suggesting that they remained a latent source of vulnerability to future depression-like responses to stress. Imipramine reversed the suppressed BDNF gene expression by triggering a compensatory mechanism, acetylation, in which molecular activators attach themselves to the gene and over...

Tuberculosis still a risk for patients receiving HIV drugs

...r weakened immune status can allow reactivation of latent TB infection, according to lead author Enrico Gira...ith HIV should continue to screen for and to treat latent tuberculosis infection in their patients, even if they have minor levels of immune suppression or ar...

NIAID researchers show how promising TB drug works

...compound may be useful in treating both active and latent TB. (For information about the first clinical trial of PA-824, see June 14, 2005, NIAID press release: http://www3.niaid.nih.gov/news/newsreleases/2005/tb_pa_824.htm .) PA-824 must be chemically activated in the bacterium before it exerts its anti-...

Researchers discover why melanoma is so malignant

...n't related to cancer, but rather demonstrates the latent ability of melanocytes to travel Finally, the research team found that when Slug was knocked out in melanoma cells, the cancer was unable to metastasize when placed into a mouse. "This work is yet another demonstration of the notion that certain e...

Tropical Deforestation affects rainfall in the U.S. and around the globe

... the atmosphere when water vapor condenses, called latent heat," said Avissar. "Associated changes in air pressure distribution shift the typical global circulation patterns, sending storm systems off their typical paths." And, because of the Amazon's location, any sort of weather hiccup from the area could...

Menopause Symptoms May Come Back After Stopping Menopausal Hormone Therapy

...in cancer formation by leading to the outgrowth of latent cancer cells. In looking at studies on the use of supplements for menopause, Warren reports that the seven clinical trials using black cohosh were largely flawed but might suggest some effectiveness. However, little evidence exists for beneficial ef...

Women cautioned against using herbal supplements

...in cancer formation by leading to the outgrowth of latent cancer cells. In looking at studies on the use of supplements for menopause, Warren reports that the seven clinical trials using black cohosh were largely flawed but might suggest some effectiveness. However, little evidence exists for beneficial ef...

Scientists track stealth DNA elements in primate evolution

...c DNA sequences that appear to have persisted in a latent state for long periods of time may not be simply lying dormant. Instead, the researchers say that these elements have played a crucial role in human evolution by surreptitiously spawning hyperactive progeny copies, giving rise to the most abundant fa...

Field of beams - Novel system uses polarized light pulses to reveal crop health

...nfections. The simplest models entirely ignore the latent period of a disease: the period of time when an in...els often assume that the rate of progression from latent to infectious, and infectious to recovered, is constant, irrespective of the time already spent in t...

Inhaling large amounts of salt can cause hypertension

...nfections. The simplest models entirely ignore the latent period of a disease: the period of time when an in...els often assume that the rate of progression from latent to infectious, and infectious to recovered, is constant, irrespective of the time already spent in t...

Understanding biases in epidemic models important when making public health predictions

...nfections. The simplest models entirely ignore the latent period of a disease: the period of time when an in...els often assume that the rate of progression from latent to infectious, and infectious to recovered, is constant, irrespective of the time already spent in t...

Random gene expression may drive HIV into hiding

...searchers found evidence that the virus may become latent in some cells by harnessing the random molecular b...uzzled over how HIV makes the "decision" to become latent or to keep replicating in a certain cell. "Most of the other groups studying the molecular mechanis...

Touching Molecules With Your Bare Hands

... the ever vigilant immune sentinels of its host. A latent virus can escape immune detection if it resides in...led episomes. When an infected B cell divides, the latent gamma-herpes virus episome must replicate and segregate into daughter cells along with the cell’s ge...

How A Latent Virus Eludes Immune Defenses

... the ever vigilant immune sentinels of its host. A latent virus can escape immune detection if it resides in...led episomes. When an infected B cell divides, the latent gamma-herpes virus episome must replicate and segregate into daughter cells along with the cell’s ge...

U-M team recovers ancient whale in Egyptian desert

...pril 22 issue of Science. "We think this may be a latent ability that all mammals have -- potentially even humans -- and we're just harnessing it and turning it on and off, inducing a state of hibernation on demand," said Roth, a member of Fred Hutchinson's Basic Sciences Division. During a hibernation-li...

Buying Time Through Hibernation on Demand

...pril 22 issue of Science. "We think this may be a latent ability that all mammals have -- potentially even humans -- and we're just harnessing it and turning it on and off, inducing a state of hibernation on demand," said Roth, a member of Fred Hutchinson's Basic Sciences Division. During a hibernation-li...

Viral protein influences key cell-signaling pathway

...L is an aggressive disease characterized by a long latent period and the proliferation of T lymphocytes. The virus is spread by sexual activity, by contact with infected blood and by infected women to children through breast milk. HTLV-1, like its cousin HIV, inserts its genetic information permanently int...

Jefferson Virologists Coax HIV Out of Hiding

...aldifferent drugs to determine what stimulated the latent virus the best.“To our surprise, it was IL-7,?he says. “We don’t know why, but it isthe best agent in terms of its ability to stimulate HIV out of latencythat we’ve seen in the last 15 years.?They found that the virus wasstimulated to higher levels a...

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