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Tag: "large" at biology news

Inexpensive, mass-produced genes core of synthetic biology advances at UH

...shed we could rapidly synthesizemany variations of large naturally occurring genes. The costs ofcurrent tec...se treatment. It also couldallow for production of large molecules that do not occur naturally,but that are needed for new generations of vaccines and therap...

New Technique for Tracking Gene Regulators

... sequence them.While small in length, the tags are large enough to allow computersearches to locate their specific positions on the complete genome in amanner that is analogous to a laser scanner reading barcodes on itemsin the grocery store. In this case the inventory isn’t cans of food butthe database of...

Bacteria collection sheds light on urinary tract infections

...rinking contaminated water. Without access to the large collection of bacteria strains from the Gastroenteric Disease Center, it would have been difficult for the researchers to carry out the research, according to DebRoy. The Gastroenteric Disease Center has been collecting E.coli samples since 1965 and ...

Whole genome fine map of rice completed

...erence between the two strains is small, there are large differences in intergenic regions. The study also analyzed the duplication history of the rice genome. Eighteen pairs of apparent duplications were discovered, covering 65.7% of the genome. Among them, 17 pairs happened before the divergence of the g...

U-M scientist to talk about tissue engineering at AAAS

...body needs a jumpstart," Krebsbach said. To heal a large wound, like that created when a cancerous tumor is removed from the jaw, that often means taking a bone graft from someplace like the hip. That approach has problems both for the wound at the donor site and for the site where it is implanted. In add...

U of M researcher examines newly emerging deadly disease

...king superantigens (bacterial toxins that activate large numbers of T cells), often leading to death due to hypertension and shock. Purpura fulminans has been identified in five cases in the Minneapolis-St. Paul, Minn., metropolitan area during 2000-2004, as described in the April 1, 2005 issue of Clinical...

Study finds more than one-third of human genome regulated by RNA

...vides thefirst evidence that microRNAs influence a large percentage of life'sfunctions.The team developed a computational method to define the relationshipbetween microRNAs and their target genes. In December 2003, the samegroup identified 400 genes in the human genome targeted by microRNAs.(Prior to this ...

The secret lives of whales

...and watch the collective migration of species over large portions of an ocean basin. “So if I am a whale off Newfoundland, I can hear a whale off Bermuda,?says Clark. Singing whales appear to slalom from one geographic feature to the next using the echoes of their intense, infrasonic voices to navigate. Th...

NYU researchers simulate molecular biological clock

...vides thefirst evidence that microRNAs influence a large percentage of life'sfunctions.The team developed a computational method to define the relationshipbetween microRNAs and their target genes. In December 2003, the samegroup identified 400 genes in the human genome targeted by microRNAs.(Prior to this ...

Gene therapy converts dead bone graft to new, living tissue

...juries whose treatment involves the replacement of large sections of bone. Cancers such as osteosarcoma, one of the most common types of bone cancers, or tumors that occur adjacent to bones, often must be treated by removing the diseased section of bone and replacing it with the only alternative available ...

Researchers reveal the infectious impact of salmon farms on wild salmon

... farms are having a significant impact over a very large area." The researchers isolated the effect of the... the rivers and head to sea, traveling en masse in large mixed schools. Thus the scientists could see the effect on the salmon as they moved toward the farm....

An HIV Protein Plays a Surprising Role in Gene Activation

... to associate with the TATA box is called TFIID, a large protein complex containing a protein that binds the TATA box (aptly named the TATA-box-binding protein, or TBP) and several cofactors called TBP-associated factors (TAFs). PIC assembly sometimes also requires activator proteins, which can enhance tra...

Automatic extraction of gene/protein biological functions from biomedical text

...tations of genes are quite useful for interpreting large amounts of high-throughput data efficiently, the demand for automatic extraction of information related to gene functions from text has been increasing. Results: We have developed a method for automatically extracting the biological process function...

Spider Venom Could Yield Eco-Friendly Insecticides

...ntains funnel-web spider (Hadronyche versuta) -- a large Australian spider with a bite that is deadly to humans and insects -- is an ideal source of venom for King's research. The spider "cooperates" by rearing up in a fighting stance when provoked, making it relatively easy for researchers to aspirate ven...

Solution to Pollution: New Bacteria Eats Toxic Waste

...ersity in the Netherlands. “PAHs have contaminated large amounts of sediment in the Netherlands, and doing this naturally through bioremediation is the most cost-effective way to treat the contaminated sediments.?/p> The research involves many levels of cooperation between the sciences and engineering ...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...nfusions, treatment requires weekly injection of a large amount of the enzyme. "Gene therapy has the potential to reverse the course of the disease with a single treatment," Koeberl said. The researchers delivered the glycogen-degrading enzyme with an adeno-associated virus (AAV) vector. AAV is not assoc...

Purdue proves concept of using nano-materials for drug discovery

...to chemotherapy drugs produce a disproportionately large number of the pumps, causing the cells to become p... millions of untested drug compounds that exist in large pharmaceutical "libraries." The chips could dramatically increase the number of experiments that are...

In the sea slug's defense against lobsters, confusion is key

...rsive chemicals, Aplysia's inky secretion contains large quantities of chemicals that are also found in the food of spiny lobsters and that indeed these chemicals serve to activate nervous-system pathways that control feeding behaviors of the lobster. The inky secretion also stimulates other behaviors in t...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

...n unraveling this mystery, the researchers studied large regions of the genome and identified the DNA sequences associated with chromatin that contains "on" tags. DNA is the same in all the cells in our body. What makes the cells do different jobs is that different genes are turned on. For example, the set...

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

...of a vaccine against S. pneumoniae.“CbpA is a very large protein,?Tuomanen said. “Now that we know whatit looks like and how it’s put together, we can pull it apart to see ifsmaller pieces of it can be used to make a vaccine that triggersproduction of antibodies against the CbpA. Since all the S. pneumonia...

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