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Tag: "lack" at biology news

Cells re-energize to come back from the brink of death

...esearch has shown that cells that become cancerous lack caspase and other proteins needed to support apopt...locking this enzyme would kill abnormal cells that lack caspase activation and cannot undergo apoptosis. That strategy would be the basis of novel anti-canc...

Discovery in orange cauliflower may lead to more nutritious crops

...-carotene, they are limited partially because they lack a "metabolic sink," or a place to store the compound. Developing staple crops with more vitamin A is important because vitamin A deficiency, common in developing countries, leads to compromised immune systems and is the leading cause of blindness i...

Women well informed about breast cancer, yet lacking knowledge about current treatments

...These survey results suggest that many women still lack essential disease treatment information, which reinforces the need for women to educate themselves to help get the best treatment,” said Diane Blum, MSW, executive director of CancerCare. “While great progress has been made in breast cancer awarenes...

College students who pull 'all-nighters' and get no sleep more likely to have a lower GPA

...ctivity and performance. Recent studies associate lack of sleep with serious health problems such as an increased risk of depression, obesity, cardiovascular disease and diabetes. ...

New findings challenge established views on human genome

...logists. According to ENCODE researchers, this lack of evolutionary constraint may indicate that many species’ genomes contain a pool of functional elements, including RNA transcripts, that provide no specific benefits in terms of survival or reproduction. As this pool turns over during evolutionary t...

Plants recognize their siblings, biologists discover

...provide a cue for kin recognition.” Though they lack cognition and memory, the study shows plants are capable of complex social behaviours such as altruism towards relatives, says Dudley. Like humans, the most interesting behaviours occur beneath the surface. Dudley and her student, Amanda File, ob...

Exploring the dark matter of the genome

... had little or no function, because it appeared to lack the protein-coding genes that occur so richly in the chromosomes' more accessible and better-studied euchromatin," says Karpen, a senior scientist in Berkeley Lab's Life Sciences Division and an adjunct professor of cell and molecular biology at the ...

Research finds that circadian rhythms dominate all life functions

...become chaotic in states of consistent lighting or lack of lighting, but it never stops. Comparing the c...n can be impacted by daylight and darkness -- or a lack of both. For example, while gene expression oscillates in mice exposed to a constant state of dim li...

Potent possibilities for parasite attack

... Peacock, first author on the report. "Given their lack of similarity to human genes, they present a limited repertoire of potential targets for drug and vaccine development allowing researchers to optimise the use of limited resources." Leishmaniasis is one of the neglected diseases that desperately ...

Potato wart eyed as risk to potato production

...s. The long-term survival of fungal spores and the lack of suitable chemical controls for potato wart suppression make this disease especially problematic for any type of cultivated potato production, including small garden plots and subsistence farming to extensive land areas economically dependent on co...

Researchers demonstrate way to control tree height

...ssible in any tree species, but are limited by the lack of research into gene transfer methods for most ornamental and forest trees. However, usable methods are already available for sweet gum, elm, black locust and pines. The current successful modification with poplar could be just “the tip of the icebe...

Gene therapy study shows safety and statistically significant improvement in Parkinson's disease

...h advanced Parkinson’s disease demonstrated both a lack of adverse events related to the gene therapy procedure and statistically significant improvements from baseline in both clinical symptoms and abnormal brain metabolism (as measured by positron emission tomography, or PET scanning). Although all pati...

Genome of Clostridium botulinum reveals the background to world's deadliest toxin

... research into clostridia has been hampered by the lack of a good genetic system. Professor Nigel Minton, Professor of Applied Molecular Microbiology at The University of Nottingham, has developed new methods to knock out genes in clostridia. "Even after decades of research, only a handful of mutants h...

'Smart' mice teach scientists about learning process, brain disorders

Mice genetically engineered to lack a single enzyme in their brains are more adept at learning than their normal cousins, and are quicker to figure out that their environment has changed, a team led by researchers at UT Southwestern Medical Center has found. The results, appearing t...

NASA-funded robotic sub finds bottom of world's deepest sinkhole

...izing features, but cenote walls, while irregular, lack distinctive features. To overcome this challenge, DEPTHX had to navigate by recognizing a more global response from all of its sensors. Wettergreen said demonstrating that SLAM could work in such a featureless environment suggests that it will hav...

Human stem cell treatment restores motor function in paralyzed rats

...ily blocked with a clamp. After 30 minutes, this lack of blood flow can result in the death of specialized spinal cord neurons called spinal inhibitory neurons, leading to irreversible spasticity and rigidity, or loss of muscle control, in the lower limbs, even though the spinal cord is intact. “The ...

Mice with a migraine show signs of brain damage

...cally, some parts of the brain still suffer from a lack of oxygen. The problem begins as the brain tries to recover from CSD, which throws the proportion of crucial ions like potassium and sodium out of balance, taking away the brain’s ability to function efficiently. This change in the proportion of c...

Salk scientists hammer out a pathway that promotes muscle cell survival in mice

...lth was restored in mice genetically engineered to lack CREB and suffering from muscle weakness as a result. "We’ve discovered that SIK1 provides a completely unexpected link between two important mechanisms of gene regulation, CREB and HDAC, and have shown that this pathway plays a major role in ...

Scripps research team sheds light on long-sought cold sensation gene

...served the behavior of mice genetically altered to lack the gene in response to cold stimuli. When placed in compartments with a temperature gradient, or in an enclosure where they could choose between two temperatures, mice without TRPM8 showed essentially no preference in the temperature range of 18...

Keeping the immune system from starting a 'food fight'

... or conditions of nutrient excess. In fat cells, a lack of STAMP2 led to aberrant inflammatory responses to both nutrients and acute inflammatory stimuli, they reported. Similarly, they showed that the visceral fat surrounding the internal organs of STAMP2-deficient mice became inflamed, and the animal...

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